Platelet and mean platelet volume kinetics in adult patients with sepsis

The aims of this study were to evaluate the kinetics of platelet counts and mean platelet volume (MPV) in adults with sepsis and to determine whether the responses are infection-specific. This retrospective cohort study included patients admitted to a tertiary-care teaching hospital with microbiologically proven nosocomial sepsis between January 2006 and January 2011. Platelet counts and MPV measurements were examined daily for 5 days after the onset of sepsis. During the study period, 151 of the 214 sepsis episodes were associated with thrombocytopenia. Gram-positive microorganisms were the most frequently isolated. The decrease in platelet counts was statistically significant for the first 3 days of sepsis in Gram-positive septic patients, for 4 days in Gram-negative septic patients and for all 5 days in fungal septic patients (p<0.001). The increase in MPV values was statistically significant for the first 3 days of sepsis in Gram-positive septic patients and for all 5 days in the other groups (p<0.001). We conclude that fungal sepsis has a stronger association with thrombocytopenia and increased MPV. © 2015 Informa UK Ltd. All rights reserved: reproduction in whole or part not permitted.

Yazar Aydemir H.
Piskin N.
Akduman D.
Kokturk F.
Aktas E.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/7030
Tek Biçim Adres 10.3109/09537104.2012.701027
Konu Başlıkları Mean platelet volume
Platelet count
Sepsis
Thrombocytopenia
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Platelets
Dergi Cilt Bilgisi 26
Dergi Sayısı 4
Sayfalar 331 - 335
Yayın Yılı 2015
Eser Adı
[dc.title]
Platelet and mean platelet volume kinetics in adult patients with sepsis
Yazar
[dc.contributor.author]
Aydemir H.
Yazar
[dc.contributor.author]
Piskin N.
Yazar
[dc.contributor.author]
Akduman D.
Yazar
[dc.contributor.author]
Kokturk F.
Yazar
[dc.contributor.author]
Aktas E.
Yayın Yılı
[dc.date.issued]
2015
Yayıncı
[dc.publisher]
Informa Healthcare
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
The aims of this study were to evaluate the kinetics of platelet counts and mean platelet volume (MPV) in adults with sepsis and to determine whether the responses are infection-specific. This retrospective cohort study included patients admitted to a tertiary-care teaching hospital with microbiologically proven nosocomial sepsis between January 2006 and January 2011. Platelet counts and MPV measurements were examined daily for 5 days after the onset of sepsis. During the study period, 151 of the 214 sepsis episodes were associated with thrombocytopenia. Gram-positive microorganisms were the most frequently isolated. The decrease in platelet counts was statistically significant for the first 3 days of sepsis in Gram-positive septic patients, for 4 days in Gram-negative septic patients and for all 5 days in fungal septic patients (p<0.001). The increase in MPV values was statistically significant for the first 3 days of sepsis in Gram-positive septic patients and for all 5 days in the other groups (p<0.001). We conclude that fungal sepsis has a stronger association with thrombocytopenia and increased MPV. © 2015 Informa UK Ltd. All rights reserved: reproduction in whole or part not permitted.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Mean platelet volume
Konu Başlıkları
[dc.subject]
Platelet count
Konu Başlıkları
[dc.subject]
Sepsis
Konu Başlıkları
[dc.subject]
Thrombocytopenia
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0953-7104
İlk Sayfa Sayısı
[dc.identifier.startpage]
331
Son Sayfa Sayısı
[dc.identifier.endpage]
335
Dergi Adı
[dc.relation.journal]
Platelets
Dergi Sayısı
[dc.identifier.issue]
4
Dergi Cilt Bilgisi
[dc.identifier.volume]
26
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.3109/09537104.2012.701027
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/7030
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
15
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
19 Şubat 2024 17:16
Google Kontrol
Tıklayınız
sepsis patients septic Gram-positive counts platelet fungal significant statistically thrombocytopenia January Gram-negative decrease values increase stronger permitted reproduction reserved rights groups Informa increased association frequently conclude isolated responses admitted included cohort retrospective infection-specific whether teaching
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

creativecommons
Bu site altında yer alan tüm kaynaklar Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.
Platforms