Platelet lymphocyte ratio and neutrophil lymphocyte ratio are predictors of ST segment resolution following thrombolytic treatment

BACKGROUND: The platelet/lymphocyte ratio (PLR) and neutrophil/lymphocyte ratio (NLR) are associated with inflammation and atherosclerosis. Our aim is to investigate the relationship between ST segment resolution and these inflammation markers in patients with ST segment elevation myocardial infarction (STEMI) following thrombolytic treatment. METHODS: We included 55 patients suffering from STEMI who were administered thrombolytic treatment and met the inclusion criteria. The sum of ST segment elevation was measured at presentation and 60–90 minutes after administration of the thrombolytic agent. According to the sum of STR, patients were divided into two groups (patients with STR >50% vs. those with STR ?50%). RESULTS: In this study, 58.2% (N.=32) and 41.8% (N.=23) of patients were found to have STR>50% and STR?50%, respectively. Time to treatment was significantly higher in the STR?50% group than in the STR>50% group (3.3±2.78 h, 1.99±1.4 h, P=0.024). There was no statistically significant association between STR and neutrophil, lymphocyte, platelet, white blood cell count, mean platelet volume, plateletcrit, hemoglobin, serum glucose and urea. NLR was significantly higher in the STR?50% group than in the STR>50% group (4.51±3.24 vs. 3.92±6.50, P=0.044). The PLR was also significantly higher in the STR?50% group (140±79 vs. 102±69, P=0.030). CONCLUSIONS: Admission PLR and NLR might be valuable in the prediction of impaired ST segment resolution following thrombolysis in patients with STEMI. © 2018 EDIZIONI MINERVA MEDICA

Dergi Adı Gazzetta Medica Italiana Archivio per le Scienze Mediche
Dergi Cilt Bilgisi 178
Dergi Sayısı 5
Sayfalar 307 - 313
Yayın Yılı 2019
Eser Adı
[dc.title]
Platelet lymphocyte ratio and neutrophil lymphocyte ratio are predictors of ST segment resolution following thrombolytic treatment
Yazar
[dc.contributor.author]
Kalayci B.
Yazar
[dc.contributor.author]
Kaçmaz C.
Yazar
[dc.contributor.author]
Köktürk F.
Yayın Yılı
[dc.date.issued]
2019
Yayıncı
[dc.publisher]
Edizioni Minerva Medica
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
BACKGROUND: The platelet/lymphocyte ratio (PLR) and neutrophil/lymphocyte ratio (NLR) are associated with inflammation and atherosclerosis. Our aim is to investigate the relationship between ST segment resolution and these inflammation markers in patients with ST segment elevation myocardial infarction (STEMI) following thrombolytic treatment. METHODS: We included 55 patients suffering from STEMI who were administered thrombolytic treatment and met the inclusion criteria. The sum of ST segment elevation was measured at presentation and 60–90 minutes after administration of the thrombolytic agent. According to the sum of STR, patients were divided into two groups (patients with STR >50% vs. those with STR ?50%). RESULTS: In this study, 58.2% (N.=32) and 41.8% (N.=23) of patients were found to have STR>50% and STR?50%, respectively. Time to treatment was significantly higher in the STR?50% group than in the STR>50% group (3.3±2.78 h, 1.99±1.4 h, P=0.024). There was no statistically significant association between STR and neutrophil, lymphocyte, platelet, white blood cell count, mean platelet volume, plateletcrit, hemoglobin, serum glucose and urea. NLR was significantly higher in the STR?50% group than in the STR>50% group (4.51±3.24 vs. 3.92±6.50, P=0.044). The PLR was also significantly higher in the STR?50% group (140±79 vs. 102±69, P=0.030). CONCLUSIONS: Admission PLR and NLR might be valuable in the prediction of impaired ST segment resolution following thrombolysis in patients with STEMI. © 2018 EDIZIONI MINERVA MEDICA
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Blood platelets
Konu Başlıkları
[dc.subject]
Lymphocytes
Konu Başlıkları
[dc.subject]
Neutrophils
Konu Başlıkları
[dc.subject]
ST elevation myocardial infarction
Konu Başlıkları
[dc.subject]
Thrombolytic therapy
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0393-3660
İlk Sayfa Sayısı
[dc.identifier.startpage]
307
Son Sayfa Sayısı
[dc.identifier.endpage]
313
Dergi Adı
[dc.relation.journal]
Gazzetta Medica Italiana Archivio per le Scienze Mediche
Dergi Sayısı
[dc.identifier.issue]
5
Dergi Cilt Bilgisi
[dc.identifier.volume]
178
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.23736/S0393-3660.18.03787-7
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/7032
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
43
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 06:28
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Tıklayınız
patients segment STR?50% thrombolytic significantly higher treatment STR>50% platelet following between elevation inflammation resolution lymphocyte neutrophil association significant statistically BACKGROUND MINERVA EDIZIONI thrombolysis impaired prediction valuable Admission CONCLUSIONS 102±69 volume (140±79 glucose hemoglobin plateletcrit markers
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