Lipid parameters, insulin, HBA1c and CRP levels in children with impaired glucose tolerance and impaired fasting glucose [Bozulmuş açlik glukozu ve bozulmuş glukoz toleransi olan hastalarda lipid parametreleri, insülin, HBA1c ve CRP düzeyleri]

Atherosclerosis rates are higher in adult diabetic patients than normal population and is one of the major causes of death. The main reason of this is that serum lipid and lipoprotein levels are impaired, increasing the risk for atherosclerosis. For this reason, it is needed to investigate the alterations of serum lipid parameters in patients with impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) and their effects on atherosclerosis and coronary artery disease (CAD). In this study, we measured lipid parameters, HbA1c, insulin and CRP levels in IGT and IFG patients and aimed to evaluate if they are under risk to develop atherosclerosis and diabetes mellitus (DM). Serum triglyceride, insulin and CRP levels were found to be significantly high in IGT group, and serum triglyceride, HbA1c, insulin and CRP in IFG group, than the control group. Serum HDL-cholesterol level was found to be significantly low in both study groups than the control. While serum triglyceride level was higher in IFG group than IGT group, LDL-cholesterol and HbA1c levels were significantly higher in IGT group than IFG group. Also BMI values of control group were found to be significantly lower than both IFG and IGT groups. The results we obtained from this study showed that IFG and IGT patients are under high risk for atherosclerosis and CAD due to dyslipidemia and increased CRP levels and increased level of HbA1c may show that oxidant effects may be increased related with non-enzymatic glycosidation and related metabolic stress. Also CRP level may be a good parameter for follow-up of disease and complications in IGT and IFG patients.

Yazar Gürel A.
Artmucu F.
Ünalacak M.
Atmaca H.
Aydin M.
Yayın Türü Conference Object
Tek Biçim Adres https://hdl.handle.net/20.500.12628/6486
Konu Başlıkları Atherosclerosis
CRP
Dyslipidemia
IFG
IGT
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
Dergi Adı Ondokuz Mayis Universitesi Tip Dergisi
Dergi Cilt Bilgisi 20
Dergi Sayısı 1
Sayfalar 5 - 9
Yayın Yılı 2003
Eser Adı
[dc.title]
Lipid parameters, insulin, HBA1c and CRP levels in children with impaired glucose tolerance and impaired fasting glucose [Bozulmuş açlik glukozu ve bozulmuş glukoz toleransi olan hastalarda lipid parametreleri, insülin, HBA1c ve CRP düzeyleri]
Yayın Türü
[dc.type]
conferenceObject
Özet
[dc.description.abstract]
Atherosclerosis rates are higher in adult diabetic patients than normal population and is one of the major causes of death. The main reason of this is that serum lipid and lipoprotein levels are impaired, increasing the risk for atherosclerosis. For this reason, it is needed to investigate the alterations of serum lipid parameters in patients with impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) and their effects on atherosclerosis and coronary artery disease (CAD). In this study, we measured lipid parameters, HbA1c, insulin and CRP levels in IGT and IFG patients and aimed to evaluate if they are under risk to develop atherosclerosis and diabetes mellitus (DM). Serum triglyceride, insulin and CRP levels were found to be significantly high in IGT group, and serum triglyceride, HbA1c, insulin and CRP in IFG group, than the control group. Serum HDL-cholesterol level was found to be significantly low in both study groups than the control. While serum triglyceride level was higher in IFG group than IGT group, LDL-cholesterol and HbA1c levels were significantly higher in IGT group than IFG group. Also BMI values of control group were found to be significantly lower than both IFG and IGT groups. The results we obtained from this study showed that IFG and IGT patients are under high risk for atherosclerosis and CAD due to dyslipidemia and increased CRP levels and increased level of HbA1c may show that oxidant effects may be increased related with non-enzymatic glycosidation and related metabolic stress. Also CRP level may be a good parameter for follow-up of disease and complications in IGT and IFG patients.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Yılı
[dc.date.issued]
2003
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/6486
Yayın Dili
[dc.language.iso]
tur
Konu Başlıkları
[dc.subject]
Atherosclerosis
Konu Başlıkları
[dc.subject]
CRP
Konu Başlıkları
[dc.subject]
Dyslipidemia
Konu Başlıkları
[dc.subject]
IFG
Konu Başlıkları
[dc.subject]
IGT
Yazar
[dc.contributor.author]
Gürel A.
Yazar
[dc.contributor.author]
Artmucu F.
Yazar
[dc.contributor.author]
Ünalacak M.
Yazar
[dc.contributor.author]
Atmaca H.
Yazar
[dc.contributor.author]
Aydin M.
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1300-2996
Yazar Departmanı
[dc.contributor.department]
Zonguldak Bülent Ecevit Üniversitesi
İlk Sayfa Sayısı
[dc.identifier.startpage]
5
Son Sayfa Sayısı
[dc.identifier.endpage]
9
Dergi Adı
[dc.relation.journal]
Ondokuz Mayis Universitesi Tip Dergisi
Dergi Sayısı
[dc.identifier.issue]
1
Dergi Cilt Bilgisi
[dc.identifier.volume]
20
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
15
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
07 Şubat 2024 11:27
Google Kontrol
Tıklayınız
patients levels significantly atherosclerosis increased higher triglyceride impaired control insulin effects disease groups related glucose parameters reason HDL-cholesterol Atherosclerosis LDL-cholesterol non-enzymatic complications follow-up parameter stress metabolic glycosidation oxidant dyslipidemia showed obtained results values measured needed
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

creativecommons
Bu site altında yer alan tüm kaynaklar Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.
Platforms