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Tear function and ocular surface after muller muscle-conjunctival resection

Uğurbaş, Suat Hayri | Alpay, Atilla | Bahadır, Burak | Uğurbaş, Silay Cantürk

Muller muscle-conjunctival resection (MCR) is a surgical technique to correct mild and moderate ptosis. In this study, tear function tests and ocular surface are evaluated in patients who underwent unilateral surgery. Sixteen patients with normal preoperative tear function who underwent unilateral MCR were evaluated prospectively. The fellow eyes of the patients were taken as the control group. A dry eye assessment questionnaire, Schirmer testing, tear film break-up time, fluorescein stain, Rose-Bengal stain, and conjunctival impression cytology were used to assess the tear film functions and ...Daha fazlası

Article 2014 Indian Journal of Ophthalmology62 ( 5 ) , pp. 6 - 655 566 Görüntülenme
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The effects of tadalafil and pentoxifylline on apoptosis and nitric oxide synthase in liver ischemia/reperfusion injury

Bektaş, Sibel | Karakaya, Kemal | Can, Murat | Bahadır, Buarak | Güven, Berrak | Erdoğan, Nilsen | Özdamar, Şükrü Oğuz

The aim of this study was to investigate the effects of tadalafil (TDF) and pentoxifylline (PTX) on hepatic apoptosis and the expressions of endothelial and inducible nitric oxide synthases (eNOS and iNOS) after liver ischemia/reperfusion (IR). Forty Wistar albino rats were randomly divided into five groups (n = 8) as follows: sham group; IR group with ischemia/reperfusion alone; low-dose and high-dose TDF groups received 2.5 mg/kg and 10 mg/kg TDF, respectively; and PTX group received 40 mg/kg PTX. Blood was collected for the analysis of serum alanine aminotransferase, aspartate aminotransfer ...Daha fazlası

Article 2016 Kaohsiung Journal of Medical Sciences32 ( 7 ) , pp. 3 - 347 849 Görüntülenme

Surgeon performed continuous intraoperative ultrasound guidance decreases re-excisions and mastectomy rates in breast cancer

Karadeniz Çakmak, Güldeniz | Emre, Ali U. | Taşçılar, Öğe | Bahadır, Burak | Özkan, Selçuk

Background Intraoperative ultrasound guided (IUG) breast conserving surgery (BCS) is being increasingly embraced by breast surgeons worldwide. We aimed to compare the efficacy of IUG-BCS for palpable and nonpalpable breast cancer with respect to margin status, re-excision rate, tissue sacrifice and cost-time analysis. Methods Intraoperative localization protocol includes intraoperative ultrasound prior to excision to localize the lesion and guide the initial resection. The excised specimen was then examined visually and by palpation and the specimen and cavity was examined with ultrasound. Fro ...Daha fazlası

Article 2017 Breast33 , pp. 2 - 28 590 Görüntülenme
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The relation between gleason score, and nuclear size and shape factors in prostatic adenocarcinoma

Bektaş, Sibel | Bahadır, Burak | Doğan Gün, Banu | Kertiş, Gürkan | Özdamar, Şükrü Oğuz

Aim: The aim of this study was to assess the size and shape characteristics of prostatic adenocarcinoma cell nuclei using a computer-assisted analysis system, and to compare the results with the Gleason score. Materials and Methods: Morphometric nuclear parameters, such as roundness factor, form ellipse, area, length, and perimeter, were evaluated based on specimen slides of 130 prostatic adenocarcinoma cases (77% needle biopsies and 23% prostatectomy specimens) using a computerized image analysis system. Correlation analysis between Gleason score and morphometric results was performed. Result ...Daha fazlası

Article 2009 Turkish Journal of Medical Sciences39 ( 3 ) , pp. 3 - 387 848 Görüntülenme
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Uterine serous carcinoma arising from endometrial polyp: A case report

Bektaş, Sibel | Bahadır, Burak | Barut, Figen | Bayar, Ülkü | Özdamar, Şükrü Oğuz

Seröz karsinom, tip II endometrial karsinomun tipik bir örneğidir. Sigara içme, diabetes mellitus ve hipertansiyon hikayesi olan 71 yaşındaki kadın hasta postmenapozal kanama şikayeti ile başvurmuştur. Küretaj materyalinde adenokarsinom tanısı almıştır. Histerektomi materyalinde uterusta polipoid kitlbelirlenmiştir. Histopatolojik olarak endometrial polipden gelişen seröz karsinom gözlenmiştir. İmmünhistokimyasal olarak tümör hücrelerinde p53 ve c-erbB-2 ile diffüz, östrojen ve progesteron reseptörü ile fokal reaksiyon saptanmıştır. Olgumuz, diabetes mellitus ve hipertansiyon hikayesine sahip ...Daha fazlası

Other 2009 GORM:Gynecology Obstetrics & Reproductive Medicine15 ( 1 ) , pp. 5 - 60 762 Görüntülenme

Effects of Ankaferd Blood Stopper® on Bone Regeneration in Rat Calvarial Defects

Gül, Şanser | Bahadır, Burak | Kalaycı, Murat | Ankaralı, Handan | Erdem, Oktay | Karakaya, Kemal | Açıkgöz, Bektaş

Objective: The influence of Ankaferd Blood Stopper (R) (ABS) was experimentally investigated on calvarial defects in rats. Material and Methods: Fourteen Wistar-albino rats equally divided into two groups, control group (G1) and drug group (G2), were included in the study. In G1, only right frontal craniectomy was performed. In G2, 0.5ml ABS was topically applied with a syringe after craniectomy. Surface areas of the defects were measured after four weeks, and comparative reconstruction images with were obtained, computed tomography (CT) as well. Blood samples were also collected to evaluate p ...Daha fazlası

Article 2011 TURKIYE KLINIKLERI TIP BILIMLERI DERGISI31 ( 2 ) , pp. 3 - 396 591 Görüntülenme

Traumatic neuromas: A histopa thologic and immunohistochemical study

Özdamar, Şükrü Oğuz | Gün, Banu Doğan | Barut, Figen | Bahadır, Burak

Objective: Traumatic neuroma is an exuberant, probably nonneoplastic proliferation of a nerve occurring in response to injury or surgery. We studied six cases of traumatic neuroma with light microscopic, histochemical and immunohistochemical methods to assess the cellular compositions of these lesions. Material and Methods: Sections from the formalin-fixed parafin-embedded tissues were stained with hematoxylin-eosin, Gomori's trichrome, Verhoeff elastica-von Gieson, reticuline, and S-100 protein, Epithelial Membrane Antigen, CD34 and CD68. Results: All cases revealed large numbers of small and ...Daha fazlası

Article 2007 TURKIYE KLINIKLERI TIP BILIMLERI DERGISI27 ( 1 ) , pp. 1 - 20 631 Görüntülenme

Mast Cells and p53 Expression in Psoriasis Vulgaris

Barut, Figen | Bektaş, Sibel | Gün, Banu Doğan | Bahadır, Burak | Özdamar, Şükrü Oğuz

https://dx.doi.org/10.5336/medsci.2009-15903 https://hdl.handle.net/20.500.12628/2914

Article 2011 TURKIYE KLINIKLERI TIP BILIMLERI DERGISI31 ( 2 ) , pp. 3 - 327 779 Görüntülenme

Surgeon performed intraoperative ultrasound guidance with real - time specimen scanning may allow selective cavity shavings to reduce positive margin rates

Çakmak, Güldeniz Karadeniz | Emre, Ali Uğur | Bahadır, Burak | Gençoğlu, Atalya

WOS: 000397930400303

Proceedings 2017 BREAST32 462 Görüntülenme
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Protective effects of erythropoietin against acute lung injury in a rat model of acute necrotizing pancreatitis

Taşçılar, Öğe | Çakmak, Güldeniz Karadeniz | Tekin, İshak Özel | Emre, Ali Uğur | Uçan, Bülent Hamdi | Bahadır, Burak | Açıkgöz, Serefden | İrkörücü, Oktay | Karakaya, Kemal | Balbaloğlu, Hakan | Kertiş, Gürkan | Ankaralı, Handan | Cömert, Mustafa

AIM: To investigate the effect of exogenous erythropoietin (EPO) administration on acute lung injury (ALI) in an experimental model of sodium taurodeoxycholate-induced acute necrotizing pancreatitis (ANP). METHODS: Forty-seven male Wistar albino rats were randomly divided into 7 groups: sham group (n = 5), 3 ANP groups (n = 7 each) and 3 EPO groups (n = 7 each). ANP was induced by retrograde infusion of 5% sodium taurodeoxycholate into the common bile duct. Rats in EPO groups received 1000 U/kg intramuscular EPO immediately after induction of ANP Rats in ANP groups were given 1 mL normal salin ...Daha fazlası

Article 2007 WORLD JOURNAL OF GASTROENTEROLOGY13 ( 46 ) , pp. 6 - 6182 1351 Görüntülenme
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Histological subgroups in classic kaposi sarcoma: A preliminary study

Kandemir, Nilüfer Onak | Gün, Banu Doğan | Barut, Figen | Yurdakan, Gamze | Bahadır, Burak | Bektaş, Sibel | Gün, Mustafa | Keser, Sevinç Hallaç | Özdemir, Nagehan | Özdamar, Şükrü Oğuz

Background and Design: Kaposi sarcomas (KS) are vascular tumors with a low malignant potential which include overlapping infectious, immunologic, and neoplastic processes. Recently, many histological subtypes have been defined. Material and Method: In the present study, 151 cutaneous classic KS lesions in 56 patients were retrospectively evaluated with regard to histological subtypes. Determination of the subtypes was based on the predominant histopathological component in the lesion. We examined changes in epidermis and dermis along with intratumoral inflammatory response characteristics in t ...Daha fazlası

Article 2010 TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY44 ( 2 ) , pp. 7 - 78 1054 Görüntülenme
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The protective and anti-inflammatory effect of methylene blue in corrosive esophageal burns: An experimental study

Tanrıkulu, Ceren En | Tanrıkulu, Yusuf | Kılınç, Fahriye | Bahadır, Burak | Can, Murat | Köktürk, Fürüzan | Kefeli, Ayşe

BACKGROUND: In developing countries, esophageal burns are quite common. They are caused by the ingestion of corrosive substances that may lead to esophageal perforation in the short-term and stricture formation in the long-term. Prevention of stricture progression in the esophagus is the main aim of the treatment for corrosive esophageal burns. We aimed to investigate the protective and anti-inflammatory effects of methylene blue (MB) treatment on corrosive esophageal burns. METHODS: Twenty-eight rats were used in the study and randomly divided into four equal groups; group 1 (Sham), group 2 ( ...Daha fazlası

Article 2019 ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY25 ( 4 ) , pp. 3 - 323 834 Görüntülenme
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