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A preliminary study about the effects of warm priming solution on oxidative stress and postoperative atrial fibrillation in open heart surgery

Buyukates, Mustafa | Acikgoz, Serefden | Aktunc, Erol | Kandemir, Ozer | Dogan, Sait Mesut | Aydin, Mustafa

Article | 2012 | WIENER KLINISCHE WOCHENSCHRIFT124 ( 17-18 ) , pp.618 - 623

An important reason for production of ischemia and reperfusion injury and oxidative stress is the sudden and rapid changes in body temperature during the institution of cardiopulmonary bypass. The aim of this study was to investigate the effects of warm priming solution on oxidative stress and atrial fibrillation. This is a preliminary prospective study on a group of 40 patients who underwent elective coronary artery bypass grafting operation using cardiopulmonary bypass. Patients were randomized into two groups, each consisting of 20 patients; one group was primed with a solution at 20 A degrees C and the other at 36 A degrees C in . . .itially for cardiopulmonary bypass. Blood samples from both of the groups were drawn preoperatively and at the 15th and 60th min of aortic cross clamping and 24th h following the surgery. Serum malondialdehyde levels, protein carbonyl content and total antioxidant status were detected. Patients were followed for postoperative atrial fibrillation. Malondialdehyde and protein carbonyl content were found to be significantly higher and total antioxidant status was concordantly lower in the cold priming group at the 15th and 60th min, recovering to the normal range postoperatively at the 24th h. Patients in the cold priming group had developed a significantly higher rate of atrial fibrillation when compared with the patients in the warm priming group during the postoperative period. In conclusion, although this study has its limitation about the sample size it may provide an insight about the probable preventive effects of 36 A degrees C warm priming solution in oxidative stress and postoperative atrial fibrillation Daha fazlası Daha az

Relationship between neck circumference and overactive bladder in women with metabolic syndrome: a preliminary study

Akin, Yigit | Gulmez, Hakan | Savas, Murat | Aykan, Serdar | Onder, Ozde | Yucel, Selcuk

Article | 2016 | WIENER KLINISCHE WOCHENSCHRIFT128 , pp.618 - 623

To investigate relationship between overactive bladder (OAB) and metabolic syndrome (MtS) by using neck circumference (NC). In retrospective view of prospective collected data, 204 women with or without OAB were enrolled into study, between August 2012 and December 2013. All patients were administered OAB validated questionnaires (OAB-V8) and whose score was > 8 were accepted as OAB. Patients were divided into two groups and group 1 consisted of patients with OAB, group 2 consisted of patients without OAB. Demographic data with anthropometric measurements and blood analyses were recorded. Statistical analyses including receiver oper . . .ating characteristic (ROC) curves were performed; statistically significant p was < 0.05. Mean age was 41.06 +/- 9.78 years. There were 115 (56.4 %) patients in group 1, and 89 (43.6 %) patients in group 2. OAB-V8 scores were significant higher in group 1 than group 2 (p < 0.001). Waist circumference (WC) and NC measurements were statistical significant longer in group 1 than group 2 (p < 0.001). In multivariate logistic regression analyses age, body mass index, MtS, WC, and NC were statistical significant associated with OAB. In ROC curves, area under the curve (AUC) was 0.72 cm(2) for relationship between OAB and WC (p < 0.001), and AUC was 0.73 cm(2) for relationship between OAB and NC (p = 0.004). Cut-off NC and WC values for OAB were determined as 35.25 cm and 98.5 cm, respectively. OAB with metabolic syndrome seems like more common in women than in those without. NC may be a novel indicator for OAB in selected female patients with MtS Daha fazlası Daha az

Imaging findings of pulmonary granulomatosis with polyangiitis (Wegener's granulomatosis): lesions invading the pulmonary fissure, pleura or diaphragm mimicking malignancy

Guneyli, Serkan | Ceylan, Naim | Bayraktaroglu, Selen | Gucenmez, Sercan | Aksu, Kenan | Kocacelebi, Kenan | Acar, Turker

Article | 2016 | WIENER KLINISCHE WOCHENSCHRIFT128 ( 21-22 ) , pp.809 - 815

Granulomatosis with polyangiitis (GPA, formerly Wegener's granulomatosis), in which pulmonary involvement often predominates, is a multisystem granulomatous, necrotizing vasculitis that affects small and medium-sized vessels. In this study we evaluated various radiological findings of pulmonary GPA and focused on spiculated pulmonary lesions invading the pulmonary fissure, pleura or diaphragm mimicking malignancy. This retrospective study included 48 patients, aged 28-73 (mean, 47.3) years, who showed either histopathological diagnosis of GPA (n = 39) or elevated levels of the cytoplasmic anti-neutrophilic cytoplasmic antibody serum . . . marker (n = 9) between January 2003 and December 2013. All patients received a chest computed tomography (CT), and the types of pulmonary lesions were defined and evaluated. Among the 48 patients, 33 had abnormal pulmonary findings on CT. The most commonly detected pulmonary lesion types were nodules and masses (n = 126) observed in 24 patients. Cavitation, necrosis, spiculation and invasion of the fissure, pleura or diaphragm were observed in 14, 9, 10 and 6 patients, respectively. Consolidation was found in 14 patients and thickening of bronchial wall in 8 patients. Pulmonary lesion types of GPA have a wide spectrum, potentially mimicking a high number of diseases including malignancy, infection and noninfectious inflammatory diseases. A spiculated lung lesion invading the fissure, pleura or diaphragm is mostly present in malignancy, but it can be also seen in GPA Daha fazlası Daha az

Comparison of diagnostic values of procalcitonin, C-reactive protein and blood neutrophil/lymphocyte ratio levels in predicting bacterial infection in hospitalized patients with acute exacerbations of COPD

Tanriverdi, Hakan | Ornek, Tacettin | Erboy, Fatma | Altinsoy, Bulent | Uygur, Firat | Atalay, Figen | Tor, Muge Meltem

Article | 2015 | WIENER KLINISCHE WOCHENSCHRIFT127 ( 19-20 ) , pp.756 - 763

Viral or bacterial upper respiratory infections are the most common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Based on available data, no reliable parameter has been presented to distinguish between bacterial and nonbacterial exacerbations. Therefore, we compared the diagnostic value of procalcitonin (PCT) level, which is a newer marker for predicting bacterial infections in patients with AECOPD, to routine parameters such as C-reactive protein (CRP) levels and the neutrophil/lymphocyte (N/L) ratio. This study included all consecutive patients who were admitted for a diagnosis of AECOPD between J . . .anuary 1 and March 31, 2014. PCT, CRP, and the N/L ratio were assessed in addition to cultures from tracheal aspirates or sputum on the first day of admission. Patients with a pneumonic infiltration on chest radiographs, or an extrapulmonary infection focus, or whose blood samples were not obtained for PCT and/or CRP at the same time as sputum culture were excluded from the study. A total of 77 patients were included with a mean age of 71.7 +/- A 9.5 years. Bacteria were isolated in 37.4 % of the patients. Mean PCT levels were significantly higher in patients with positive sputum cultures than in patients with negative sputum cultures. The cut-off values for PCT, CRP, and the N/L ratio for predicting a bacterial infection were 0.40 ng/mL, 91.50 mg/L, and 11.5, respectively; sensitivity was 61, 54, and 61 % respectively; specificity was 67, 52, and 58 %, respectively; and the area under the curve (AUC) values were 0.64, 0.52, and 0.58, respectively. The AUC value of PCT was significantly better for predicting bacterial infection compared with the CRP level or the N/L ratio (p = 0.042). PCT was better than CRP and the N/L ratio for predicting a bacterial infection in hospitalized patients with AECOPD. However, we find PCT not so reliable in predicting bacterial infection in AECOPD due to sensitivity and specificity of less than 80 % and a low AUC value Daha fazlası Daha az

Liver abscess following radioembolization with yttrium-90 microspheres

Korkmaz, Mehmet | Bozkaya, Halil | Cinar, Celal | Sanal, Bekir | Guneyli, Serkan | Parildar, Mustafa | Oran, Ismail

Article | 2014 | WIENER KLINISCHE WOCHENSCHRIFT126 ( 23-24 ) , pp.785 - 788

Radioembolization with yttrium-90 microspheres is an accepted and useful intervention model with minimal invasion in both primary and secondary liver malignancies. Radioembolization may lead to some complications. Liver abscess is a rare complication that can occur several weeks after radioembolization treatment of liver tumor with yttrium-90 microspheres. There are only a few case reports on hepatic liver abscess observed in early term of radioembolization treatment, and our case also constitutes a rare report that may contribute to the possible future improvements in radioembolization field to get more insight into the current und . . .erstanding of the formation of some deleterious insults such as hepatic abscess Daha fazlası Daha az

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