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The UroVysion fluorescence in situ hybridization assay is an effective tool for monitoring recurrence of bladder cancer

Varella-Garcia M. | Akduman B. | Sunpaweravong P. | Di Maria M.V. | Crawford E.D.

Makale | 2004 | Urologic Oncology: Seminars and Original Investigations22 ( 1 ) , pp.16 - 19

The newly developed UroVysion fluorescence in situ hybridization (FISH) probe was applied to urine specimens from 19 patients being monitored for recurrence of bladder cancer. The results for the multi-target DNA FISH assay were compared with independent analyses of urine cytology and flexible cystoscopy. Patients with tumors identified through the cystoscopy exam were biopsied and/or underwent surgery. In 12 patients with normal cytoscopy, cytology and FISH were also normal. Therefore, the specificity of these two tests was 100%. In 7 patients, a tumor was diagnosed by cystoscopy, and 3 of them had abnormal urine cytology while 6 o . . .f them had an abnormal result in the FISH assay. Accordingly, the sensitivity was 43% for the cytology and 87% for the FISH test. Interestingly, a pT1G3 tumor in a bladder diverticulum was not detected by cytology or the FISH test. These results agreed with a large series previously published using similar FISH probes and support the proposal for a multicenter trial to confirm the usefulness of the UroVysion probe as a screening tool to select patients for cystoscopy. © 2004 Elsevier Inc. All rights reserved Daha fazlası Daha az

Public awareness of testicular cancer and self-examination in Turkey: A multicenter study of Turkish Urooncology Society

Kuzgunbay B. | Yaycioglu O. | Soyupak B. | Kayis A.A. | Ayan S. | Yavascaoglu I. | Cal C.

Makale | 2013 | Urologic Oncology: Seminars and Original Investigations31 ( 3 ) , pp.386 - 391

Background: Testicular self-examination is the easiest and cheapest way to scan testicular cancer. However, the public awareness about testicular self-examination is very low. We aimed to investigate the public awareness of Turkish people about testicular cancer and testicular self-examination. Methods: We performed a survey consisting of 10 questions concerning testicular cancer and testicular self-examination in 799 students in the first year of 12 different medical schools. Aiming for a common method of data collection, the questionnaires were administered to the students during a class just before the lesson started. The whole d . . .ata from all of the centers were pooled in a common data-base file. Results: Eighty-nine (11.1%) of the participants reported that they had knowledge about testicular cancer, but only 11 (1.4%) of them answered all the questions about testicular cancer correctly. Eight (1%) of the participants reported that they had been performing testicular self-examination routinely once a month. Four (0.5%) of them were both well informed about testicular cancer and had been performing testicular self-examination once a month as suggested. Conclusion: The present study showed that awareness on testicular cancer and testicular self-examination is very low and suggests a need for efforts in Turkey to increase public awareness and education. © 2013 Elsevier Inc Daha fazlası Daha az


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