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Craniofacial differences according to AHI scores of children with obstructive sleep apnoea syndrome: Cephalometric study in 39 patients

Özdemir H. | Altin R. | Sögüt A. | Çinar F. | Mahmutyazicioglu K. | Kart L. | Uzun L.

Article | 2004 | Pediatric Radiology34 ( 5 ) , pp.393 - 399

Background: Cephalometry is useful as a screening test for anatomical abnormalities in patients with obstructive sleep apnoea syndrome (OSAS). Objective: To evaluate comprehensively the cephalo metric features of children with OSAS, with or without adenotonsillar hypertrophy, and to elucidate the relationship between cephalometric variables and apnoea-hypopnoea index (AHI) severity. Materials and methods: The study population consisted of 39 children, aged 4-12 years, with OSAS. Cephalometry was analysed using 11 measurements of the bony structures, their relationships and the size of the airways. Additionally, adenoid and tonsillar . . . hypertrophy were graded. Results: Cranial base angles (BaSN and BaSPNS) were found to correlate with increasing levels of AHI scores (P < 0.001). Protrusion of the maxilla (SNA) and mandible (SNB) did not correlate with AHI scores (P > 0.05). The length of the mandibular plane (GnGo) and the minimal posterior airway space (MPAS) were inversely correlated with AHI scores (P < 0.001). There was positive correlation between MPAS and GnGo (r = 0.740, P < 0.001), and negative correlation between MPAS and gonial angle (ArGoGn) (r = -0.541, P < 0.001). There was significant correlation between cephalometric data and adenotonsillar hypertrophy concerning BaSN, BaSPNS, ArGoGn, GnGoH, BaN-GnGo, MPAS, GnGO and MPH (P < 0.001). Conclusions: There is significant correlation between cephalometric data and AHI score severity in children with OSAS. Adenotonsillar hypertrophy affects the cephalometric measurements adversely. The study clearly mandates the institution of early and effective therapy of adenotonsillar hypertrophy in children with OSAS. © Springer-Verlag 2004 Daha fazlası Daha az

Erratum: Isovaleric acidaemia: Cranial CT and MRI findings (Pediatric Radiology (2004) vol. 34 (160-162))

Sogut A. | Acun C. | Aydin K. | Tomac N. | Demeril F. | Aktuglu C.

Erratum | 2006 | Pediatric Radiology36 ( 9 ) , pp.393 - 399

[No abstract available]

Isovaleric acidaemia: Cranial CT and MRI findings

Sogut A. | Acun C. | Aydin K. | Tomsac N. | Demirel F. | Aktuglu C.

Article | 2004 | Pediatric Radiology34 ( 2 ) , pp.160 - 162

Isovaleric acidaemia is an inborn error of leucine metabolism due to deficiency of isovaleryl-CoA dehydrogenase, which results in accumulation of isovaleric acid in body fluids. There are acute and chronic-intermittent forms of the disease. We present the cranial CT and MRI findings of a 19-month-old girl with the chronic-intermittent form of isovaleric acidaemia. She presented with severe metabolic acidosis, hyperglycaemia, glycosuria, ketonuria and acute encephalopathy. Cranial CT revealed bilateral hypodensity of the globi pallidi. MRI showed signal changes in the globi pallidi and corticospinal tracts of the mesencephalon, which . . . were hypointense on T1-weighted and hyperintense on T2-weighted images Daha fazlası Daha az

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