Filtreler
Screening for patients with mild Alzheimer disease using frequency doubling technology perimetry

Aykan U. | Akdemir M.O. | Yildirim O. | Varlibas F.

Conference Object | 2013 | Neuro-Ophthalmology37 ( 6 ) , pp.239 - 246

We compared the visual field performances of patients with mild Alzheimer disease (AD) with normal subjects and detected visual field impairment attributable to the magnocellular pathway using frequency doubling technology - Matrix (FDT-Matrix). We recruited 43 patients with mild AD (mean age: 68.0±7.2 years) and 33 controls who are visually and cognitively normal (mean age: 64.1±6.4 years). All participants had at least two reliable FDT-Matrix 30-2 tests. Reliability indices, global indices (mean deviation and pattern standard deviation), and glaucoma hemifield test results were measured with FDT-Matrix. The mean test duration was . . .significantly longer in patient group compared with controls (p=0.002). Among the reliability indices, false negatives were higher in patient group than controls (p=0.003). There were statistically significant differences in mean deviation and pattern standard deviation values ( Daha fazlası Daha az

Erratum: Optical coherence tomography in patients with relapsing-remitting multiple sclerosis without optic neuritis: A 20-month longitudinal study (Neuro-Ophthalmology (2013) 37 (104-110))

Huseyinoglu N. | Ozben S. | Ekinci M. | Buyukuysal C. | Kale M.Y. | Sanivar H.S. | Cagatay H.H.

Erratum | 2013 | Neuro-Ophthalmology37 ( 4 ) , pp.239 - 246

[No abstract available]

Bilateral optic perineuritis developing with intracranial fibrillary astrocytoma

Çagavi F. | Kalayci M. | Ünal A. | Kargi Ş. | Gül Ş. | Erdem L.O. | Gün B.D.

Article | 2005 | Neuro-Ophthalmology29 ( 05.Jun ) , pp.201 - 205

Optic perineuritis is an uncommon variety of orbital inflammatory disease. A case with a 45-day history of headache and vomiting who was diagnosed with fibrillary astrocytoma of the right frontal lobe is reported. Progressive bilateral visual loss developing postoperatively was considered as bilateral optic perineuritis based on the pathological and radiological findings. However, extensive medical and surgical therapy failed to recover visual loss. By this case, the mechanisms and difficulties in the diagnosis were discussed. Copyright © Taylor & Francis Inc.

Relationship between structural and functional assessment of the visual system in mildly disabled relapsing-remitting multiple sclerosis patients

Huseyinoglu N. | Ekinci M. | Ozben S. | Buyukuysal C.

Article | 2014 | Neuro-Ophthalmology38 ( 1 ) , pp.1 - 7

Studies that explored the anterior visual pathway in the patients with multiple sclerosis (MS) have demonstrated contradictory results about the correlation between structural and functional status of optic nerve and retina. We aimed to investigate the functional and structural findings in our cohort of mildly disabled relapsing-remitting MS patients. A total of 134 eyes (80 eyes of the patients with MS and 54 eyes of the control group) were investigated. Eyes of MS patients were divided into two groups as eyes with history of optic neuritis (ON group) and without history of optic neuritis (NON group). Ophthalmological investigation . . . including visual evoked potentials, standard automated perimetry, and optical coherence tomography were performed for all participants. Retinal and macular thicknesses were significantly decreased in ON and NON groups compared with controls. Also, visual evoked potential latencies and visual field loss were worse in the both MS groups compared with control group. We did not find any correlation between visual evoked potentials and retinal or macular thickness values but visual field parameters were correlated between retinal and macular layer loss in the NON group. According to our results and some previous studies, although both functional and structural changes were detected in patients with MS, functional status markers do not always show parallelism (or synchrony) with structural changes, especially in eyes with history of optic neuritis. © 2014 Informa Healthcare USA, Inc Daha fazlası Daha az

Optical coherence tomography in patients with relapsing-remitting multiple sclerosis without optic neuritis: A 20-month longitudinal study

Huseyinoglu N. | Ozben S. | Ekinci M. | Buyukuysal C. | Yildirim M. | Safak H. | Huseyin H.

Article | 2013 | Neuro-Ophthalmology37 ( 3 ) , pp.104 - 110

Optical coherence tomography is supported and used as a technique for visualisation of neuro-axonal loss in multiple sclerosis, but there are also a few studies expressing the opposite view. The aim of our study was to investigate retinal nerve fibre layer and optic nerve head parameters in patients with multiple sclerosis without a history of prior optic neuritis and symptoms of a new clinical attack during the follow-up for a total of 20-month period. Full ophthalmic evaluation was performed for all of the participants. The baseline retinal nerve fibre layer and macular thicknesses and focal and global loss of macular volume value . . .s were significantly lower in the eyes of the patients with multiple sclerosis compared with the healthy controls. No significant change between baseline and follow-up scans were found in all optical coherence tomography parameters in the multiple sclerosis group. Statistical analyses revealed significant retinal nerve fibre layer and macular thickness differences between baseline and second measurements in the controls. No significant difference in percent change between baseline and second measurements was observed between the patient and control groups. We conclude that whereas healthy subjects have an age-related tendency toward a decrease in retinal nerve fibre layer thickness, patients with multiple sclerosis patients are likely to pass through different stages of retinal thinning and thickening due to subclinical optic neuritis and, as a result, we could not detect any statistically significant change between baseline and second measurements in our multiple sclerosis patients. © Informa Healthcare USA, Inc Daha fazlası Daha az

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