Evaluation of lipid peroxidation, oxidant/antioxidant status, and serum nitric oxide levels in alopecia areata

Koca R. | Armutcu F. | Altinyazar H.C. | Gürel A.

Background: The pathophysiology of alopecia areata (AA) has not been clearly defined; however, it appears as a tissue-restricted autoimmune disease mediated by T lymphocytes. Immunohistochemical studies have shown peri- and infra-follicular inflammatory infiltrate which damages hair follicles. We analyzed the role of lipid peroxidation and oxidant-antioxidant enzymes in the pathogenesis of AA. Material/Methods: Twenty-four patients with AA and 20 age- and sex-matched healthy controls were enrolled in this study. We analyzed serum levels of malondialdehyde (MDA) and nitric oxide (NO) and the se ...Daha fazlası

Is Pipelle biopsy really adequate for diagnosing endometrial disease?

Tanriverdi H.A. | Barut A. | Gün B.B. | Kaya E.

Backgound: The purpose of our research was to determine the reliability and accuracy of the Pipelle device in acquiring an adequate and representative endometrial sample and to compare it with D&C histology. Material/Methods: A total of 127 women were prospectively included in the study. After Pipelle endometrial sampling, classic dilatation and curettage (D&C) was performed. The histological results of both techniques were compared to assess the accuracy of Pipelle sampling. Prior to endometrial sampling, transvaginal ultrasonography was performed to determine endometrial thickness and pathol ...Daha fazlası

Autopsy evaluation of coal mining deaths in the city of Zonguldak, Turkey

Ozer E. | Yilmaz R. | Evcuman D. | Yildirim A. | Cetin I. | Kocak U. | Ergen K.

Background: In this study, our aim was to evaluate the fatal occupational accidents that occurred in Zonguldak coal mines between the years 2005-2008. Material/Methods: We retrospectively evaluated 42 fatal coal mine occupational accidents in Zonguldak (Turkey) between the years 2005-2008. The forensic records of autopsies referred to the chief prosecutors' office during 2005-2008 were reviewed retrospectively. There were 42 cases. The cases were evaluated with respect to age, mechanism of injury, body region of wound, cause of death, and legality of the mine. Results: Ages of the deceased ran ...Daha fazlası

The evaluation of serum cystatin C, malondialdehyde, and total antioxidant status in patients with metabolic syndrome

Demircan N. | Gürel A. | Armutcu F. | Ünalacak M. | Aktunç E. | Atmaca H.

Background: This study was designed to determine if serum cystatin C (Cys C) levels are affected by metabolic syndome and whether they correlate with lipid peroxidation and total antioxidant status (TAS) in this disorder. Material/Methods: Cases with metabolic syndrome diagnosed according to the ATP III criteria (18 females, 12 males) were compared with healthy control subjects (20 females, 17 males) matched by age and gender. Plasma Cys C, malondialdehyde (MDA), and TAS levels were studied. Results: Compared with the controls, Cys C and MDA levels were significantly higher (p

Potential drug–drug interactions with antimicrobials in hospitalized patients: A multicenter point-prevalence study

Kuscu F. | Ulu A. | Inal A.S. | Suntur B.M. | Aydemir H. | Gul S. | Ecemis K.

Background: Improper use of antimicrobials can cause adverse drug events and high costs. The purpose of this study was to investigate the frequency and potential drug–drug interactions associated with antimicrobials among hospitalized patients. Material/Methods: This study was conducted on the same day in 5 different hospitals in Turkey. We included patients aged ?18 years who received at least 1 antimicrobial drug and at least 1 of any other drug. The Micromedex® online drug reference system was used to control and describe the interactions. Drug interactions were classified as con-traindicat ...Daha fazlası

Dyspeptic complaints after 20 weeks of gestation are not related to Helicobacter pylori seropositivity

Tanriverdi H.A. | Ustundag Y. | Tekin I.O. | Barut A.

Background: This study was to test whether an association exists between Helicobacter pylori seropositivity and severity of dyspeptic symptoms after 20 weeks of gestation in pregnant women. Material/Methods: Pregnant women (n=103) with gestational ages between 20-41 weeks and healthy non-pregnant women (controls, n=79) were prospectively enrolled in the study. Anti-H. pylori IgG serum antibody was tested to establish seropositivity. The dyspeptic symptoms were evaluated by the Glasgow Dyspepsia Severity Score in the pregnant group and classified as asymptomatic (score 0), mildly symptomatic (s ...Daha fazlası

Emphysema and airflow obstruction in non-smoking coal miners with pneumoconiosis

Altınsoy B. | Öz İ.İ. | Erboy F. | Tor M. | Atalay F.

Background: Accumulating evidence shows that functional impairment in subjects with coal workers’ pneumoconiosis (CWP) is principally due to emphysema and airflow obstruction, rather than underlying restrictive mechanisms. However, cigarette smoking has remained a major confounder. The aim of this study was to assess whether coal dust exposure was associated with emphysema and/or airflow obstruction in the absence of smoking history. Material/Method: The subjects evaluated for possible pneumoconiosis between 2013 and 2015 were retrospectively enrolled into this study. After excluding those wit ...Daha fazlası

Prophylactic anticonvulsants in patients undergoing craniotomy: A single-center experience

Kale A.

Background: There is no consensus on the efficacy of seizure prophylaxis in patients undergoing craniotomy. Some studies show that antiepileptic use decreases the risk of seizures, but other studies do not support this. The present study investigated the role of antiepileptic drugs in patient undergoing craniotomy due to various intracranial pathologies. Material/Methods: A retrospective review was performed in adult patients undergoing craniotomy between January 2013 and June 2017. Results of 282 patients who did not have a history of seizures and had craniotomies for various reasons were inc ...Daha fazlası

Evaluation of social and demographic characteristics of incest cases in a university hospital in Turkey

Yildirim A. | Ozer E. | Bozkurt H. | Ozsoy S. | Enginyurt O. | Evcuman D. | Yilmaz R.

Background: Incest is defined as any sexual activity between close blood relatives including step relatives and family members who are forbidden by law to marry. It is a problem that can be seen in all the social classes in developed and undeveloped societies. The World Health Organization classifies this problem as a silent health emergency. Father-daughter incest is reported to be the most common incest type followed by the other types like brother- sister, sister-sister and mother-son incest. Material/Methods: Subjects for this study were recruited from a sample of incest cases referred to ...Daha fazlası

Arterial Stiffness and Carotid Intima Media Thickness in Diabetic Peripheral Neuropathy

AVCI AHMET, Demir Kenan, Kaya Zeynettin, Marakoglu Kamile, Ceylan Esra, Ekmekci Hakan, Yilmaz Ahmet, Demir Aysegul, Altunkeser Bulent Behlul

Emphysema and Airflow Obstruction in Non Smoking Coal Miners with Pneumoconiosis

ALTINSOY BÜLENT,ÖZ İBRAHİM İLKER,ERBOY FATMA,TOR MÜGE MELTEM,ATALAY FİGEN