Poly(3-hydroxyalkanoate)s: Diversification and biomedical applications: A state of the art review

Hazer, Derya Burcu | Kılıçay, Ebru | Hazer, Baki

Biomaterials have played an important role in the treatment of disease and the improvement of health care. Synthetic and naturally occurring biodegradable and biocompatible polymers have been used as biomaterials. Polyhydroxyalkanoates (PHAs) are promising materials for biomedical applications because they are biodegradable, non-toxic and biocompatible. We will shortly summarize the modification reactions, which include functionalization and grafting reactions, to improve the mechanical, thermal and hydrophilic properties of PHAs. The use of the modified PHAs in numerous biomedical application ...Daha fazlası

İnceleme 2012 Materials Science and Engineering C32 ( 4 ) , pp. 6 - 647 779 Görüntülenme

Synthesis of antibacterial amphiphilic elastomer based on polystyrene-block-polyisoprene-block-polystyrene via thiol-ene addition

Keleş, Elif | Hazer, Baki | Cömert, Füsun B.

A new type of amphiphilic antibacterial elastomer has been described. Thermoplastic elastomer, polystyrene-block-polyisoprene-block-polystyrene (PS-b-PI-b-PS) triblock copolymer was functionalized in toluene solution by free radical mercaptan addition in order to obtain an amphiphilic antibacterial elastomer. Thiol terminated PEG was grafted through the double bonds of PS-b-PI-b-PS via free radical thiol-ene coupling reaction. The antibacterial properties of the amphiphilic graft copolymers were observed. The original and the modified polymers were used to create microfibers in an electro-spin ...Daha fazlası

Makale 2013 Materials Science and Engineering C33 ( 3 ) , pp. 1 - 1066 726 Görüntülenme

A novel poly(propylene-co-imidazole) based biofuel cell: System optimization and operation for energy generation

Kılıç, Muhammet Samet | Korkut, Şeyda | Hazer, Baki

This study describes the construction of an enzymatic fuel cell comprised of novel gold nanoparticles embedded poly(propylene-co-imidazole) coated anode and cathode. Working electrode fabrication steps and operational conditions for the fuel cell have been optimized to get enhanced power output. Electrical generation capacity of the optimized cell was tested by using the municipal wastewater sample. The enzymatic fuel cell system reached to maximum power density with 1 µg and 8 µg of polymer quantity and bilirubin oxidase on electrode surface, respectively. The maximum power output was calcula ...Daha fazlası

Makale 2015 Materials Science and Engineering C47 , pp. 1 - 171 1287 Görüntülenme

Erişime Açık

The operation of enzymatic fuel cell fabricated with rationally designed poly(caprolactone-g-ethylene glycol) copolymers

Korkut, Şeyda | Kılıç, Muhammet Samet | Sanal, Timur | Hazer, Baki

This study describes construction of an enzymatic fuel cell comprised of poly(caprolactone-g-ethylene glycol) coated novel glucose oxidase anode and laccase cathode. Rationally designed poly(caprolactone-g-ethylene glycol) containing various poly(ethylene glycol) percentages ranging between 2.67 and 15.04% were synthesized chemically and tested separately for operation of the fuel cell system to achieve the best energy generation. The maximum power density was found to be 80.55 µW cm- 2 at 0.91 V (vs. Ag/AgCl) in pH 5, 100 mM citrate buffer (20 °C) by the addition of 30 mM of glucose from the ...Daha fazlası

Makale 2017 Materials Science and Engineering C76 , pp. 7 - 793 1222 Görüntülenme

Sintering effects of mullite-doping on mechanical properties of bovine hydroxyapatite

Yetmez M. | Erkmen Z.E. | Kalkandelen C. | Ficai A. | Oktar F.N.

In this study, sintering effects on microstructural behavior of bovine derived hydroxyapatite doped with powder mullite are considered in the temperature range between 1000 °C and 1300 °C. Results show that maximum values of both compressive strength and microhardness are achieved in the samples sintered at 1200 °C for all mullite additions of 5, 7.5, 10 and 12.5 wt%. Moreover, above 1000 °C, decomposition of HA and new phase formations such as whitlockite and gehlenite play a major role in both compressive strength and microhardness properties which increase up to 10 wt% mullite reinforcement ...Daha fazlası

Makale 2017 Materials Science and Engineering C77 , pp. 4 - 475 394 Görüntülenme

Erişime Açık

High fluorescence emission silver nano particles coated with poly (styrene-g-soybean oil) graft copolymers: Antibacterial activity and polymerization kinetics

Hazer, Baki | Kalaycı, Özlem A.

Autoxidation of poly unsaturated fatty acids makes negative effect on foods. In this work, this negative effect was turned to a great advantage using autoxidized soybean oil as a macroperoxide nanocomposite initiator containing silver nano particles in free radical polymerization of vinyl monomers. The synthesis of soybean oil macro peroxide was carried out by exposing soybean oil to air oxygen with the presence of silver nanoparticles (Ag NPs) at room temperature. Autoxidized soybean oil macroperoxide containing silver nanoparticles (Agsbox) successfully initiated the free radical polymerizat ...Daha fazlası

Makale 2017 Materials Science and Engineering C74 , pp. 2 - 269 626 Görüntülenme

Collagen-infilled 3D printed scaffolds loaded with miR-148b-transfected bone marrow stem cells improve calvarial bone regeneration in rats

Moncal K.K. | Aydin R.S.T. | Abu-Laban M. | Heo D.N. | Rizk E. | Tucker S.M. | Lewis G.S.

Differentiation of progenitors in a controlled environment improves the repair of critical-sized calvarial bone defects; however, integrating micro RNA (miRNA) therapy with 3D printed scaffolds still remains a challenge for craniofacial reconstruction. In this study, we aimed to engineer three-dimensional (3D) printed hybrid scaffolds as a new ex situ miR-148b expressing delivery system for osteogenic induction of rat bone marrow stem cells (rBMSCs) in vitro, and also in vivo in critical-sized rat calvarial defects. miR-148b-transfected rBMSCs underwent early differentiation in collagen-infill ...Daha fazlası

Makale 2019 Materials Science and Engineering C105 249 Görüntülenme

Filtreler

Koleksiyon [15]

İlgili Araştırmacılar [5]

Ambargo Durumu [1]

Tam Metin [2]

Yazar [21]

Yayın Türü [2]

Yayın Yılı [5]

Yayın Dili [1]

Dergi Adı [1]

Yayıncı [1]

Konu Başlıkları [31]