Bilateral synchronous squamous cell tonsil carcinoma treated with chemoradiotherapy

Bakkal, Bekir Hakan | Ugur M.B. | Bahadir B.

Article | 2014 | Journal of the Pakistan Medical Association64 ( 4 ) , pp.468 - 470

The incidence of numerous head and neck tumours is a known issue though bilateral synchronous tonsillar carcinoma reports are so uncommon that only 20 cases were found in a literature review. Most of these patients were treated with bilateral tonsillectomy followed by adjuvant radiotherapy. We report, to our knowledge, the first case of bilateral synchronous tonsillar squamous cell carcinoma treated only with chemoradiotherapy without tonsillectomy.

Ovarian cancer during pregnancy

Barut A. | Arikan I. | Barut F. | Harma M. | Harma M.I. | Payasli B.

Article | 2011 | Journal of the Pakistan Medical Association61 ( 9 ) , pp.914 - 916

The frequency of cancer during pregnancy is approximately 1 per 1000 live births. This rate may increase as more women postpone childbirth until later in life, when cancer becomes more frequent. Pregnancy affectsmanagement of the cancer, and the cancer affects the management of pregnancy. The most common malignancies, in order of frequency, are breast cancer, leukaemia and lymphomas as a group, melanoma, gynaecologic cancers, and bone tumours. Ovarian tumours are found in about 1 in 1000 pregnancies and 3-6% of these are malignant. Thus, ovarian cancer occurs in approximately 1 in 12,500-25,000 pregnancies. Here, we report a case of . . . ovarian mucinous carcinoma that was diagnosed at 22 weeks of gestation. After conservative surgery, she was given three cycles of carboplatin chemotherapy. She delivered at 33 weeks of gestation and after undergoing surgery she was given six cycles of paclitaxel and carboplatin chemotherapy. The patient is now being followed by the oncology department with no evidence of disease Daha fazlası Daha az

T-cell/histiocyte-rich large B-cell lymphoma of stomach

Barut F. | Kandemir N.O. | Gun B.D. | Ozdamar S.O.

Article | 2016 | Journal of the Pakistan Medical Association66 ( 7 ) , pp.905 - 907

T-cell/histiocyte-rich large B-cell lymphoma is an unusually encountered lymphoid neoplasm of stomach with aggressive course, and is an uncommon morphologic variant of diffuse large B-cell lymphoma. An ulceratedmass, 7x5x1 cm in size was observed within the gastrectomy specimen of a 76-year-old female patient. In cross sections, besides mature lymphoid cells displaying T-cell phenotype, a neoplastic formation composed of large, pleomorphic atypical lymphoid cells with, prominent nucleoli, vesicular nuclei and abundant eosinophilic cytoplasm displaying B-cell phenotype were observed. Meanwhile, histiocyte-like mononuclear cells and R . . .eed-Sternberg-like multinuclear cells expressing CD68 and Mac387 were also observed. The diagnosis of the case was T cell/histiocyte-rich large B-cell lymphoma. This rarely encountered neoplasm should be kept in mind in the differential diagnosis of primary gastric lymphomas. © 2016, Pakistan Medical Association. All rights reserved Daha fazlası Daha az

Recurrent partial hydatidiform mole

Barut A. | Arikan I. | Harma M. | Harma M.I. | Barut F. | Coskan A.

Article | 2011 | Journal of the Pakistan Medical Association61 ( 10 ) , pp.1016 - 1017

Hydatidiform moles are abnormal conceptions characterised by atypical hyperplastic trophoblasts and hydropic villi. Their incidence is approximately 1 in 1000 pregnancies. The recurrence risk of hydatidiform mole is approximately 1 in 60 in a subsequent pregnancy and 1 in 6.5 in the third pregnancy. In cases with recurrence, the majority of moles are of the same type as that in the preceding pregnancy. Here, we describe the case of a recurrent partial hydatidiform mole after an initial healthy pregnancy. Both pregnancies were evacuated by suction curettage, and the patient was followed by serial monitoring of ß-human chorionic gonad . . .otropin levels. Recurrent molar pregnancy is not an indication for chemotherapy, and subsequent pregnancies do not have an increased risk for other obstetric complications Daha fazlası Daha az

The effect of bariatric anaesthesia on postoperative pulmonary functions

Piskin Ö. | Altinsoy B. | Çimencan M. | Aydin B.G. | Okyay D. | Kücükosman G. | Tasçilar Ö.

Article | 2017 | Journal of the Pakistan Medical Association67 ( 4 ) , pp.561 - 567

Objective: To evaluate respiratory function in the post-operative early period of patients undergoing bariatric surgery using the sleeve gastrectomy technique. Methods: This prospective, observational study was conducted at Bülent Ecevit University Health Application and Research Centre, Zonguldak, Turkey from June to December 2014, and comprised patients with planned bariatric sleeve gastrectomy under general anaesthesia. Participants were visited 12-24 hours before the operation to record accompanying diseases and demographic data. Before the operations, respiratory function test, maximum expiratory pressure, maximum inspiratory p . . .ressure and arterial blood gas assessment tests were done and recorded as T0. After one hour of the operation, Aldrete scores ?9 and the above-mentioned tests were repeated and recorded as T1. SPSS 18 and MedCalc were used for statistical analysis. Results: Of the 76 participants, 60(78%) were women and 16(21%) were men. The overall median age was 39 years (inter-quartile range: 32-47 years). The mean and median values for forced expiratory volume in 1 second, forced vital capacity, maximum inspiratory pressure, maximum expiratory pressure and the ratio between partial pressure of oxygen in arterial blood and fraction of inspired oxygen at T0 were 101±17, 102±17, 66 (interquartile range: 59-74), 114 (interquartile range: 100-138) and 379±49, respectively, compared with 78±18, 76±18, 53 (interquartile range: 48-59), 85 (interquartile range: 73-95) and 331±49at T1 ( Daha fazlası Daha az

Unilateral ovarian agenesis and clear cell type epithelioid leiomyoma of uterus mimicking ovarian malignancy

Bay U.O. | Gun B.D. | Ungan B. | Dogan S. | Barut A. | Arikan I.I.

Article | 2014 | Journal of the Pakistan Medical Association64 ( 1 ) , pp.561 - 567

A case of unilateral absent ovary together with clear cell type epithelioid leiomyoma of uterus mimicking ovarian malignancy discovered during laparotomy is presented. Unilateral absence of an ovary is an extremely rare finding. Although the exact pathophysiological mechanism is not known, it could result from a defect in embryological development or asymptomatic torsion of ovary. Clear cell type epithelioid leiomyoma of uterus is also a rare variant, composed of round or polygonal 'clear' cells rather than typical spindle-shaped cells and ultra structurally differs from non-uterine counterparts.

Primary pulmonary sarcoma metastasising to the skin during pregnancy

Arikan I. | Barut A. | Harma M. | Harma M.I. | Erdem Z. | Gezer S.

Article | 2012 | Journal of the Pakistan Medical Association62 ( 12 ) , pp.1342 - 1343

Lung cancer during pregnancy is a rare situation which is being increasingly reported during the past two decades due to a rising trend of cigarette smoking among young women and the tendency to delay pregnancy to a later age in life. We describe the case of a 32-year-old woman with primary pulmonary sarcoma, diagnosed at 31st week of pregnancy. X-ray chest and thoracic magnetic resonance imaging revealed a 9 × 6 cm mass in the left mediastinum, with tracheal shift, and pleural effusion. Biopsy performed during broncoscopy, was reported as mesenchymal tumour. She delivered a baby by Caesarean section at the 32nd week of gestation du . . .e to the development of superior vena cava syndrome. A skin biopsy taken 3 weeks later from the nodular lesion at the periumblical region was reported as a tumour metastasis. She received radiotherapy for 10 days, but died in the intensive care unit. Malignancies, even those as uncommon as a pulmonary sarcoma, should be considered in the differential diagnosis of pleural effusion during pregnancy Daha fazlası Daha az

Selenium, copper, zinc, iron levels and mortality in patients with sepsis and systemic inflammatory response syndrome in Western Black Sea Region, Turkey

Ayoglu H. | Sezer Ü. | Akin M. | Okyay D. | Ayoglu F. | Can M. | Kücükosman G.

Article | 2016 | Journal of the Pakistan Medical Association66 ( 4 ) , pp.447 - 452

Objective: To evaluate the changing levels of selenium, copper, zinc and iron in patients with sepsis and systemic inflammatory response syndrome and their influence on mortality. Methods: The prospective study was conducted at a tertiary care university hospital in Zonguldak city in the western Black Sea region of Turkey from January 2012 to December 2013, and comprised patients with sepsis and systemic inflammatory response syndrome. Blood samples were taken on 1st, 3rd, 5th and 7th days to measure serum selenium, copper, zinc and iron levels. Patients' demographic data, presence of additional diseases and mortality were recorded. . . . Results: Of the 57 patients, 28(49.1%) were female and 29(50.9%) were male, with an overall mean age of 60.3±19.4 years, mean height of 166.1±11.4cm, mean weight of 76.5±17.5kg. Copper and zinc levels were in the normal range, while selenium and iron levels were lower than the limit values at all measuring periods. There was no significant difference between first and other days in accordance with element levels (p>0.05). Baseline copper levels in patients with malignancy were lower than patients without malignancy ( Daha fazlası Daha az

Sexual dysfunction in infertile couples: Evaluation and treatment of infertility

Ozmen Bayar U. | Inan Arikan I. | Barut A. | Harma M. | Harma M. | Basaran M. | Atasoy N.

Article | 2014 | Journal of the Pakistan Medical Association64 ( 2 ) , pp.447 - 452

Objective: To evaluate the diagnostic and the predictive value of Arizona Sexual Experience Scale among primary infertile couples regarding sexual dysfunction. Methods: The cross-sectional and prospective pre, post study comprising primary infertile patients was carried out at Bulent Ecevit University Hospital, Zonguldak, Turkey. Fifty consecutive primary infertile couples not treated previously were investigated between 2003 and 2007 for the presence of sexual dysfunction by a psychiatrist. Arizona Sexual Experience Scale scoring was self-administered to determine sexual dysfunction among couples before treatment and also 3 months . . .after the initiation of the treatment. Results: Pretreatment mean values of the index parametres in both women and men were significantly increased after treatment. Statistically significant positive correlation was observed between pre- and post-treatment total scores in both women (r=0.83; p13 (Sensitivity: 83%; Specificity: 93%), respectively. Pre- and post-treatment scores in men were >10 (Sensitivity: 65%; Specificity: 61%), >11 (Sensitivity: 83%; Specificity: 62%), respectively. Binary logistic regression analyses revealed women's pre-treatment and post-treatment scores as a significant factor for prediction of sexual dysfunction independent of sociodemographic factors (p=0.001 and p=0.001, respectively). Conclusion: Evaluation and treatment of infertility is an important risk factor for sexual dyfunction. Pre- and post-treatment Arizona Sexual Experience Scale score could be used as a screening test for sexual dysfunction and might be used to decide pre/post-treatment consultation of couples with a specialist Daha fazlası Daha az

Reduction of isolated zygomatic arch fractures using dental instrument: Report of 2 cases and review of the literature

Korkmaz Y.T. | Coskun U. | Durmuslar M.C. | Zor Z.F. | Hocaoglu T.P. | Altintas N.Y.

Article | 2016 | Journal of the Pakistan Medical Association66 ( 3 ) , pp.345 - 347

To assess the effectiveness of a dental instrument for reduction of isolated zygomatic arch fractures. Two patients were admitted to our clinic representing isolated unilateral zygomatic arch fracture. The common presenting complaints were pain, swelling and difficulty in mouth opening. Fractures were confirmed with plain radiography and computerized tomography. The fractures were reduced with upper buccal sulcus approach by dental instrument. Patients achieved satisfactory maximum mouth opening within 10 days. At follow up after 6 months, there was complete healing without any complication. This procedure is cost effective, time sa . . .ving, safe and effective to manage isolated zygomatic arch fractures under local anaesthesia with satisfactory outcomes. © 2016, University of Economics - Prague. All Reserved Daha fazlası Daha az

Primary brain T-Cell lymphoma during pregnancy

Ilker A. | Aykut B. | Muge H. | Ibrahim H.M. | Ulkua O.B. | Tugba D. | Oktay E.

Article | 2012 | Journal of the Pakistan Medical Association62 ( 4 ) , pp.395 - 396

The incidence of non-Hodgkin's lymphoma (NHL) during pregnancy is about 0.8 cases per 100,000 women. We describe a case of a 33-year-old woman with primary brain Tcell NHL who was diagnosed at the 32nd week of gestation. She visited the emergency room complaining of a headache, vomiting and drowsiness. Her pregnancy had been uneventful prior to the admission. Brain magnetic resonance imaging (MRI) revealed a mass at the anterior cranial fossa in the mid liner in the front of the lateral ventricle of the brain. She was hospitalised and monitored regarding her complaints until the foetal lungs matured. During her stay, systemic evalua . . .tion revealed no other pathology. She delivered a healthy baby in the 34th week of gestation by Caesarean section and the tumour was evacuated while under the same anaesthesia. She underwent another surgery 12 hours after the first operation because of cerebral herniation. Despite aggressive treatment in the neurosurgical intensive care unit, her condition continued to deteriorate and she died on the tenth postpartum day. Examination of the patient at necropsy revealed no other pathology. The lymph nodes and bone marrow were not involved Daha fazlası Daha az

Validity and reliability of the Turkish version of the weight self-stigma questionnaire

Erdogan Z. | Kurcer M.A. | Kurtuncu M. | Catalcam S.

Article | 2018 | Journal of the Pakistan Medical Association68 ( 12 ) , pp.1799 - 1804

Objective: To test the validity and reliability of the Turkish version of the Weight Self-Stigma Questionnaire. Methods: The methodological, descriptive study was conducted at the Bulent Ecevit University, Zonguldak, Turkey, from January to June, 2016, and comprised obese patients presenting at the Endocrinology and Diabetes polyclinic tied to the university. Data was collected using patient identification form and Weight Self-Stigma Questionnaire. SPSS 18 was used for statistical analysis. Results: Of the 151 subjects, 97(64.2%) were female and 54(35.8%) were male. Two-factor structure explained 58% of the total variance in the Wei . . .ght Self-Stigma Questionnaire. The Cronbach alpha internal consistency coefficient of the Turkish version was 0.876, indicating high internal consistency. The two factors found in the confirmatory factor analysis had Cronbach alpha values of 0.820 and 0.830. Conclusion: The validity and reliability of Weight Self-Stigma Questionnaire was found to be high in Turkey. © 2018, Pakistan Medical Association. All rights reserved Daha fazlası Daha az

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