Effect of defective collagen synthesis on epithelial implant interface: Lathyritic model in dogs. An experimental preliminary study

Cengiz M.I. | Lu T.K. | Acikgoz G. | Trisi P. | Wang H.-L.

Peri-implant mucosa is composed of 2 compartments: a marginal junctional epithelium and a zone of connective tissue attachment. Both structures consist mainly of collagen. Lathyrism is characterized by defective collagen synthesis due to inhibition of lysyl oxidase, an enzyme that is essential for interfibrillar collagen cross-linking. The lathyritic agent beta- aminoproprionitrile (ß-APN) is considered a suitable agent to disrupt the connective tissue metabolism. Therefore, the purpose of this study was to assess the effect of defective connective tissue metabolism on epithelial implant inter ...Daha fazlası

Effect of Defective Collagen Synthesis on Epithelial Implant Interface: Lathyritic Model in Dogs. An Experimental Preliminary Study

CENGİZ MURAT İNANÇ,KIRTILOĞLU TUĞRUL,AÇIKGÖZ HASAN GÖKHAN,TRİSİ PAOLA,WANG HOMLAY