Anomalous left coronary artery arising from the right sinus of Valsalva: A case report

Ozeren A. | Aydin M. | Bilge M. | Cam F.

Article | 2005 | International Journal of Cardiology101 ( 3 ) , pp.491 - 493

We report a case of 56-year-old man whose coronary angiography showed a single coronary artery arising from a single ostium in the right sinus of Valsalva. © 2004 Elsevier Ireland Ltd. All rights reserved.

Is direct method of low density lipoprotein cholesterol measurement appropriate for targeting lipid lowering therapy?

Can M. | Acikgoz S. | Mungan G. | Ugurbas E. | Ankarali H. | Sumbuloglu V. | Demirtas S.

Article | 2010 | International Journal of Cardiology142 ( 1 ) , pp.105 - 107

Objectives: The aim of this study was to compare the Friedewald Formula with direct homogeneous low density lipoprotein cholesterol (LDL-C) assay for the detection of LDL-C levels. Methods: Fasting serum samples were obtained for lipid analysis from 1001 patients. Total cholesterol (TC) and triglyceride (TG) levels were measured with enzymatic methods and the measurements of high density lipoprotein cholesterol (HDL-C) and LDL-C levels were detected using direct methods. Results: The mean levels of serum TC, TG, HDL-C and LDL-C were detected with in the reference range. The LDL-C estimated by the Friedewald formula was significantly . . . correlated (P < 0.01) with the direct method but there was a negative bias among them. Conclusion: Laboratories cannot use direct method as a substitute for Friedewald formula because direct method has not been standardized in large populations and increase cholesterol assay costs. © 2008 Elsevier Ireland Ltd. All rights reserved Daha fazlası Daha az

Assessment of P-wave duration and dispersion in patients with isolated coronary artery ectasia

Dogan S.M. | Yildirim N. | Aydin M. | Gursurer M. | Cam F. | Celik O.

Article | 2008 | International Journal of Cardiology125 ( 3 ) , pp.404 - 406

Introduction: Coronary artery ectasia (CAE) is defined as localized or diffuse dilatation of the epicardial coronary arteries. We sought to determine whether isolated CAE may alter P-wave duration and dispersion (PD). Methods: The study population consisted of 26 patients (mean age: 61.6 ± 11.0 years) with isolated CAE (group 1) and sex- and age-matched 26 control subjects (group 2). Both groups underwent a standard 12-lead surface electrocardiogram recorded at 50 mm/s. Maximal (Pmax) and minimal P-wave durations (Pmin) are measured. PD was defined as the difference between Pmax and Pmin. Results: In group 1, Pmax (114.2 ± 10.4 ms v . . .s 104.8 ± 10.6 ms, p < 0.002) and PD (34.0 ± 12.7 ms vs 24 ± 10.6, p < 0.004) were significantly higher than those of group 2. Moreover a significant correlation was found between Pmax and PD with ectatic segment number (r = 0.625, r = 0.626, respectively; p = <0.001); and Pmax and PD with ectatic vessel number (r = 0.698, r = 0.704 respectively; p = <0.0001). Conclusion: Isolated CAE and the degree of the ectasia were found to be associated with prolonged Pmax and PD. © 2007 Elsevier Ireland Ltd. All rights reserved Daha fazlası Daha az

Erratum: Letter to the Editor: Isolated interrupted aortic arch, a rare cause of hypertension in adults (International Journal of Cardiology (2008) 127 (e52-e53))

Yildirim N. | Dogan S.M. | Aydin M. | Hekimoglu K. | Gungorduk A.

Erratum | 2010 | International Journal of Cardiology138 ( 3 ) , pp.404 - 406

[No abstract available]

Isolated interrupted aortic arch, a rare cause of hypertension in adults

Yildirim N. | Dogan S.M. | Aydin M. | Hekimoglu K. | Gungorduk A.

Article | 2008 | International Journal of Cardiology127 ( 2 ) , pp.404 - 406

Interrupted aortic arch (IAA) is a rare and usually lethal congenital malformation. Patients with complete IAA very rarely do reach adult age without previous surgical intervention. The present report describes a 26-year-old asymptomatic isolated IAA case with hypertension that was incidentally diagnosed. IAA just distal to the left subclavian artery and a markedly developed collateral circulation was demonstrated by cardiac catheterization and thoracic 3D magnetic resonance angiography. This case report was also interesting that only mild arterial hypertension of the upper extremities was incidentally found in the patient. © 2007 E . . .lsevier Ireland Ltd. All rights reserved Daha fazlası Daha az

Myocardial ischemia caused by a coronary anomaly left anterior descending coronary artery arising from right sinus of Valsalva

Dogan S.M. | Gursurer M. | Aydin M. | Gocer H. | Cabuk M. | Dursun A.

Article | 2006 | International Journal of Cardiology112 ( 3 ) , pp.404 - 406

We present the case of a patient in anomalous origin of the left anterior descending coronary artery that caused myocardial ischemia and led to positive myocardial scintigraphic results. Coronary angiography showed that the left anterior descending coronary artery arose from the right coronary ostium-an anomaly that has been associated with chest discomfort-without atherosclerotic lesions. Left circumflex artery and the diagonal branches were arising from the left main coronary artery and the whole coronary tree were free of atherosclerosis. © 2006 Elsevier Ireland Ltd. All rights reserved.

Effects of dipper and non-dipper status of essential hypertension on left atrial mechanical functions

Aydin M. | Ozeren A. | Bilge M. | Dursun A. | Cam F. | Elbey M.A.

Article | 2004 | International Journal of Cardiology96 ( 3 ) , pp.419 - 424

Aim: This study was designed in order to investigate the effects of dipper and non-dipper status of hypertension on left atrial mechanical (reservoir, conduit and booster pump) functions with left atrial volume measurements by means of two-dimensional echocardiography in untreated systemic hypertensive patients. Method: A total of 27 untreated dipper hypertensive patients, group I (15 female, 12 male, mean age 57±12 years); 23 untreated non-dipper hypertensive patients, group II (12 female, 11 male, mean age: 53±18 years); and 25 voluntary healthy individuals, group III (13 female, 12 male, mean age 53±10 years) were included into t . . .he study. Twenty-four hour blood pressure (BP) measurement was performed by the cuff-oscillometric method to evaluate the nocturnal decrease of BP. The patients whose night time mean blood pressure measurements were found 10% or more lower compared to mean day time measurements were classified as dipper hypertensive patients and the ones with a decrease of less than 10% were classified as non-dipper hypertensive patients. Left atrial (LA) volumes were measured echocardiographically according to biplane area-length method in apical four-chamber and two-chamber views. LA maximal volume (Vmax) was recorded at the onset of mitral opening, LA minimal volume (Vmin) was recorded at the onset of mitral closure and LA presystolic volume (Vp) was recorded at the beginning of the atrial systole (p wave on ECG). All volume measurements were corrected to body surface area, and following LA emptying functions parameters were calculated: LA passive emptying volume (LAPEV)=Vmax-Vp, LA passive emptying fraction (LAPEF)=LAPEV/Vmax, Conduit volume (CV)=left ventricular output volume-(Vmax-Vmin), LA active emptying volume (LAAEV)=Vp-Vmin, LA active emptying fraction (LAAEF)=LAAEV/Vp, LA total emptying volume (LATEV)=V max-Vmin, LA total emptying fraction (LATEF)=LATEV/V max. Results: LA volume indexes, Vmax, Vmin, and Vp, were significantly increased in the hypertensive subgroups (groups I and II) than in controls (p<0.001, p<0.001, p<0.001, respectively), but no significant difference was found in the Vp values between group I and group II. Vmax and Vmin were larger in non-dipper hypertensive group than in dipper hypertensive group (p<0.05 and p<0.05, respectively). LAPEV and LAPEF were observed to be significantly reduced in both dipper and non-dipper hypertensives than in control (p<0.001 and p<0.05, respectively), and this difference was more obvious in non-dipper than dipper cases (p<0.001). Conduit volume was significantly lower in hypertensive groups than controls (p<0.05). LA active emptying volume (p<0.001) and LAA active emptying fraction (p<0.001) were significantly greater in hypertensive cases than in controls. Furthermore, LA active emptying volume in non-dipper hypertensive subjects was significantly greater than dipper hypertensive cases (p<0.05). Left atrial total emptying volume and left atrial total emptying fraction in both hypertensive groups were similar to control (p>0.05). Conclusions: Atrial reservoir and booster pump functions increase in hypertensive patients, but this result is more prominent in non-dipper hypertensives than in dipper hypertensive patients. © 2003 Elsevier Ireland Ltd. All rights reserved Daha fazlası Daha az

The increase in P-wave dispersion is associated with the duration of disease in patients with Behçet's disease

Dogan S.M. | Aydin M. | Gursurer M. | Yildirim N. | Tekin N. | Altinyazar C. | Onuk T.

Article | 2008 | International Journal of Cardiology124 ( 3 ) , pp.407 - 410

Aim: P-wave dispersion (PD) has been reported to be associated with inhomogeneous and discontinuous propagation of sinus impulses. Behçet's disease (BD) is a chronic multi-system disease presenting with recurrent oral and genital ulceration, and relapsing uveitis. Left ventricular diastolic dysfunction, ventricular arrhythmia and sudden cardiac death have been documented in Behçet's disease. The aim of this study was to evaluate myocardial involvement noninvasively in patients with BD by measuring PD. Methods: Study population included 29 patients with BD (group I), (16 males, mean age: 60.4 ± 10.1 years), and 45 normal (group II), . . .(23 males, mean age: 61.2 ± 12.0 years). The maximum and minimum P-wave duration (Pmax and Pmin) and PD were measured from the 12-lead surface electrocardiogram. Echocardiographic examination was also performed. Results: There was no statistically significant difference between two groups in respect to age, gender, hypertension, diabetes mellitus, hyperlipidemia and cigarette smoking (p > 0.05). Pmax and PD of patients with BD were found to be significantly higher than those of control subjects (116.2 ± 14.0 ms vs. 102.0 ± 16.5 and 49.3 ± 12.7 ms vs. 29.3 ± 8.5 ms, respectively p < 0.0001). Moreover, we found a significant positive correlation between PD with BD duration (r = 0.78, p < 0.0001). Conclusion: Pmax and PD are found to be greater in patients with BD than in controls and are related with the duration of the disease. © 2007 Elsevier Ireland Ltd. All rights reserved Daha fazlası Daha az

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