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Diurnal characteristics of heart rate variability in patients with sarcoidosis [Tagescharakteristika der Herzfrequenzvariabilität bei Sarkoidosepatienten]

Aktop Z. | Tanrıverdi H. | Uygur F. | İşleyen A. | Kalaycı B. | Gursoy Y.C. | Karabağ T.

Article | 2017 | Herz42 ( 5 ) , pp.498 - 504

Background: The aim of this study was to evaluate autonomic nervous system function by measuring heart rate variability (HRV) in patients with sarcoidosis without known cardiac manifestations. Patients and methods: The study comprised 61 participants, including 31 patients with sarcoidosis without known cardiac manifestations and 30 healthy volunteers. All participants underwent echocardiographic examination, 12-channel electrocardiography (ECG), and 24-h Holter monitoring. HRV parameters were determined and compared between the groups. Results: There were no differences between groups with regard to age, body mass index, systolic a . . .nd diastolic blood pressure, or heart rate at the time of admission. In the time domain analyses, the 24-h, daytime, and night-time standard deviations of all normal-to-normal R-R interval (SDNN) values were significantly lower in patients with sarcoidosis than those in the controls. The frequency domain analyses showed that 24-h and daytime low-frequency (LF) values, 24-h, daytime, and night-time high-frequency (HF) values were significantly lower in the patient group compared with the control group, whereas the night-time LF/HF ratio was significantly higher. Conclusion: Although Holter ECG is not a diagnostic tool for cardiac sarcoidosis, the HRV parameters, especially the night-time LF/HF values, may demonstrate increased sympathetic activation in patients with sarcoidosis. © 2016, Springer Medizin Verlag Daha fazlası Daha az

First septal artery originating from the left main coronary artery: A rare anomaly

Sayin M.R. | Akpinar I. | Karabag T. | Aydin M. | Dogan S.M.

Note | 2013 | Herz38 ( 4 ) , pp.391 - 392

[No abstract available]

Aortic elastic properties : effects of carvedilol versus nebivolol

Sayin M.R. | Aydin M. | Dogan S.M. | Karabag T. | Cetiner M.A. | Aktop Z.

Article | 2013 | Herz38 ( 3 ) , pp.299 - 305

OBJECTIVES: The aim of this study was to compare the effects of the new generation ß-blocker anti-hypertensive drugs carvedilol and nebivolol on aortic elastic properties which are important indicators of hypertension-related morbidity and mortality.METHODS: A total of 50 patients who had been diagnosed with stage 1 hypertension according to the Joint National Committee (JNC) VII criteria and who had not received any anti-hypertensive treatment were enrolled in this study. Patients were randomized to receive either 25 mg/day carvedilol (n=25) or 5 mg/day nebivolol (n=25) for 3 months at the beginning of the study. Three patients (1 . . .in the carvedilol group, 2 in the nebivolol group) who did not attend 3 month follow-up measurements were excluded from the study. The study was completed with 47 patients (25 women; mean age: 49 ± 9 years). The aortic elastic parameters such as aortic strain (AS), aortic distensibility (AD), and aortic stiffness index (ASI) were measured by echocardiography.RESULTS: Carvedilol and nebivolol provided a similar decline in both systolic and diastolic blood pressures (-12/-7 mmHg, Daha fazlası Daha az

Tirofiban in Takotsubo cardiomyopathy: Atypical broken heart syndrome with extremely fast recovery: A case report

Akpinar I. | Salihoglu Y.S. | Sayin M.R. | Elri T. | Karabag T. | Dogan S.M. | Aydin M.

Article | 2013 | Herz38 ( 1 ) , pp.89 - 92

Takotsubo cardiomyopathy, also known as broken heart syndrome, is similar to acute coronary syndrome. The absence of significant stenosis on coronary angiography and spontaneous improvement of ventricular akinesia are very important features that distinguish this syndrome from acute coronary syndromes. Despite the fact that ST segment elevations are typically encountered, atypical presentation without ECG changes should be kept in mind. We herein report the case of a 61-year-old woman who presented with mid-apical left ventricular akinesia resolving within 24 h. © 2012 Urban & Vogel, Muenchen.

Plateletcrit. A platelet marker associated with saphenous vein graft disease

Akpinar I. | Sayin M.R. | Gursoy Y.C. | Karabag T. | Kucuk E. | Buyukuysal M.C. | Aydin M.

Article | 2014 | Herz39 ( 1 ) , pp.142 - 148

Background. Saphenous vein graft disease (SVGD) after by-pass surgery is an important cause of morbidity and mortality for patients with coronary artery disease. Comprehensive evaluation of biochemical and hematological parameters associated with this problem is limited. Plateletcrit (PCT) provides complete information on total platelet mass, but it has not been previously studied. In this study, we examined the relationship between SVGD and platelet parameters such as PCT, mean platelet volume, platelet count, and platelet distribution. Methods. We retrospectively analyzed 14,398 patients who underwent coronary angiography between . . .February 2006 and August 2012. Records from 893 patients with previous coronary artery by-pass graft operation were re-evaluated. A total of 251 cases were divided into two groups (127 patients receiving a saphenous vein graft; 124 patients diagnosed with SVGD) and hematological and biochemical parameters were compared. Results. There were no significant differences in clinical characteristics between the two groups except that the SVGD group had a higher median time from surgery to coronary angiography than the patent saphenous vein graft group [7 years (2-16) vs. 5 years (2-15), Daha fazlası Daha az

Anomalous origin of left coronary artery from right sinus of Valsalva with unusual course. Interarterial left anterior descending coronary artery and retroaortic circumflex coronary artery

Sayin M.R. | Dogan S.M. | Akpinar I. | Kucuk E. | Demirtas A.O. | Yavuz N.

Article | 2014 | Herz39 ( 5 ) , pp.603 - 604

[No abstract available]

Persistent left superior vena cava, absence of the innominate vein, and upper sinus venosus defect : a rare anomaly detected using bubbles

Akpinar I. | Sayin M.R. | Karabag T. | Dogan S.M. | Sen S.T. | Gudul N.E. | Aydin M.

Article | 2013 | Herz38 ( 3 ) , pp.317 - 320

Superior vena cava anomalies are rare malformations that are typically seen with other congenital cardiac defects. Although a persistent left superior vena cava is the most common anomaly of the systemic venous return in the thorax, its combination with an upper sinus venosus defect and absence of the innominate vein is extremely rare. Here, we report a patient diagnosed with these anomalies based on a bubble study and confirmed with magnetic resonance imaging.

Left main coronary artery atresia and concomitant intercoronary communication

Sayin M.R. | Akpinar I. | Karabag T. | Aydin M. | Dogan S.M. | Gugul N.E.

Article | 2013 | Herz38 ( 7 ) , pp.798 - 800

[No abstract available]

Framingham risk score and severity of coronary artery disease

Sayin M.R. | Cetiner M.A. | Karabag T. | Akpinar I. | Sayin E. | Kurcer M.A. | Dogan S.M.

Article | 2014 | Herz39 ( 5 ) , pp.638 - 643

Objectives. Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide. Easy-to-perform and reliable parameters are needed to predict the presence and severity of CAD and to implement efficient diagnostic and therapeutic modalities. We aimed to examine whether the Framingham risk scoring system can be used for this purpose. Methods. A total of 222 patients (96 women, 126 men; mean age, 59.1±11.9 years) who underwent coronary angiography were enrolled in the study. Presence of >%50 stenosis in a coronary artery was assessed as critical CAD. The Framingham risk score (FRS) was calculated for each patient. CA . . .D severity was assessed by the Gensini score. The relationship between the FRS and the Gensini score was analyzed by correlation and regression analyses. Results. The mean Gensini score was 18.9±25.8, the median Gensini score was 7.5 (0-172), the mean FRS was 7.7±4.2, and the median FRS was 7 (0-21). Correlation analysis revealed a significant relationship between FRS and Gensini score (r=0.432, Daha fazlası Daha az

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