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Wing Stents Versus Conventional Plastic Stents in the Biliary Tree: Imagination in Plastic Biliary Stent Designs Continues to Evolve

Ustundag, Yucel | Saritas, Ulku

Letter | 2012 | DIGESTIVE DISEASES AND SCIENCES57 ( 7 ) , pp.1975 - 1976

WOS: 000305746100036 PubMed: 22623041

Colonic tuberculosis mimicking tumor perforation: A case report and review of the literature

Cömert-Beğendik, Füsun | Cömert, Mustafa | Külah, Canan | Taşçılar, Öge | Numanoğlu, Gamze | Aydemir, Selim

Article | 2006 | DIGESTIVE DISEASES AND SCIENCES51 ( 6 ) , pp.1039 - 1042

3rd European Meeting on Molecular Diagnostics -- 37910 -- Scheveningen, NETHERLANDS WOS: 000239295700002 PubMed: 16865564

The effect of sildenafil on an animal model for ischemic colitis

İrkörücü, Oktay | Taşçılar, Öğe | Çakmak, Güldeniz Karadeniz | Karakaya, Kemal | Emre, Ali Uğur | Uçan, Bülent Hamdi | Bahadır, Burak | Açıkgöz, Seferden | Ankaralı, Handan | Uğurbaş, Ebru | Cömert, Mustafa

Article | 2008 | DIGESTIVE DISEASES AND SCIENCES53 ( 6 ) , pp.1618 - 1623

Introduction Sildenafil both enhances vasodilatation by relaxing the smooth muscle in the vessels and inhibits platelet aggregation. We have therefore examined the potential benefits of sildenafil on an animal model for ischemic colitis (IC). Methods Twenty-eight female Wistar albino rats weighing 250-300 g were randomized into three experimental groups as follows: in Group 1, animals were sham operated (n = 8) and received tap water; in Groups 2 and 3, the rats underwent a standardized surgical procedure to induce IC (n = 10 in each group). Group 2 animals served as the controls, receiving only tap water, while Group 3 animals rece . . .ived 10 mg/kg sildenafil per day as a single dose for a 3-day period. All animals were sacrificed 72 h after devascularization. To determine the severity of the ischemia, we scored the macroscopically visible damage, measured the ischemic area and scored the histopathology. Tissue malondialdehyde levels were also evaluated. Results The mean area of ischemic changes were 116.80 +/- 189.93 and 0.55 +/- 1.01 mm(2) in Group 2 and 3 animals, respectively (p = 0.0001), while the macroscopically mean visible damage score decreased to 0.66 +/- 0.70 (p = 0.0001) for Group 3 animals. The Chiu scores were 0.00, 3.80 +/- 0.91 and 2.66 +/- 1.00 in Group 1, 2 and 3 animals, respectively. There was a statistically significant difference between Group 2 and 3 animals (p = 0.017). Conclusions Our findings support the view that sildenafil leads to a improvement in IC due to its well-known effects on the vascular smooth muscle and on the microcirculatory hemodynamics Daha fazlası Daha az

6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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