Karakaya, Kemal | Cömert, Mustafa | Numanoğlu, Gamze

Letter | 2009 | Clinics64 ( 12 ) , pp.1231 - 1233

[No abstract available]

Irkorucu O. | Ferahköşe Z. | Memiş L. | Ekinci O. | Akin M.

Article | 2009 | Clinics64 ( 2 ) , pp.143 - 148

BACKGROUND: Adhesion formation after peritoneal surgery is a major cause of postoperative bowel obstruction, infertility, and chronic pelvic pain. In this study, we compared the possible individual effects of phosphatidylcholine (PC), Seprafilm® II, and tissue plasminogen activator (t-PA) and the combined effects of phosphatidylcholine and t-PA on postoperative adhesion formation in a rat surgical model. MATERIALS AND METHODS: A total of 50 Wistar male rats underwent median laparotomy and standardized abrasion of the visceral and parietal peritoneum, phosphatidylcholine, Seprafilm II, and t-PA alone and phosphatidylcholine and t-PA . . .in combination were applied intraperitoneally at the end of the surgical procedure. Seven days after surgery, a relaparotomy was performed for adhesion grading and histopathological examination. RESULTS: A comparison of adhesion stages demonstrated a significant difference between the control group and the study groups ( Daha fazlası Daha az

Tascilar N. | Aydemir H. | Emre U. | Unal A. | Atasoy H.T. | Ekem S.

Letter | 2009 | Clinics64 ( 9 ) , pp.932 - 937

[No abstract available]