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A misdiagnosed keratoacanthoma turned out to be a metastatic parotid carcinoma

Tas, E. | Ugur, M. Birol | Gul, A. | Cinar, F. | Uzun, L. | Gun, B. Dogan

Article | 2010 | ACTA OTORHINOLARYNGOLOGICA ITALICA30 ( 2 ) , pp.115 - 117

Distinguishing keratoacanthoma from well-differentiated squamous-cell carcinoma is often difficult on account of the clinical and histopathological similarities between them. Since the outcome of treatment depends on identifying the correct diagnosis and having the correct treatment on time, it is essential to differentiate keratoacanthoma and squamous-cell carcinoma as soon and accurately as possible. A paradigmatic case is herein reported. An 85 year-old female underwent total parotidectomy and ipsilateral neck dissection due to the squamous-cell carcinoma of the parotid gland. The investigations, in order to determine whether the . . . tumour was a metastatic or a primary one, led to a misdiagnosis. A prior skin lesion, which was excised over her left cheek one year ago in another clinic, was diagnosed as keratoacanthoma. However, the histopathological revision of the specimen revealed that the lesion was in fact a squamous-cell carcinoma. Thus the parotid tumour was accepted as metastatic squamous-cell carcinoma rather than primary squamous-cell carcinoma Daha fazlası Daha az

Effect of vitamin B12 deficiency on otoacoustic emissions

Karli, R. | Gul, A. | Ugur, B.

Article | 2013 | ACTA OTORHINOLARYNGOLOGICA ITALICA33 ( 4 ) , pp.243 - 247

The aim of this study was to investigate the possible association between otoacoustic emission (OAE) values and cochlear function in patients with vitamin B12 deficiency and no evidence of symptomatic hearing loss. Two groups were studied: Group 1: patients with vitamin B12 deficiency; Group 2: a matched control group of patients with normal vitamin B12 levels. There was no evidence of symptomatic hearing loss in either group. Transiently evoked OAEs (TEOAEs) and spontaneous OAEs (SOAEs) were recorded. A comparative analysis of the studied parameters revealed that results at TEOAE 1000, SOAEs 1500 and SOAEs 4000 Hz were somewhat low . . .er in the vitamin B12 deficient group compared with the control group. According to our findings, there was a significant association between vitamin B12 deficiency and cochlear dysfunction. We recommend that routine vitamin B12 serum levels be determined when evaluating patients for symptomatic hearing loss Daha fazlası Daha az

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