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Stochastic resonance in hybrid scale-free neuronal networks

Yılmaz, Ergin | Uzuntarla, Muhammet | Özer, Mahmut | Perc, Matjaž

Article | 2013 | Physica A: Statistical Mechanics and its Applications392 ( 22 ) , pp.5735 - 5741

We study the phenomenon of stochastic resonance in a system of coupled neurons that are globally excited by a weak periodic input signal. We make the realistic assumption that the chemical and electrical synapses interact in the same neuronal network, hence constituting a hybrid network. By considering a hybrid coupling scheme embedded in the scale-free topology, we show that the electrical synapses are more efficient than chemical synapses in promoting the best correlation between the weak input signal and the response of the system. We also demonstrate that the average degree of neurons within the hybrid scale-free network signifi . . .cantly influences the optimal amount of noise for the occurrence of stochastic resonance, indicating that there also exists an optimal topology for the amplification of the response to the weak input signal. Lastly, we verify that the presented results are robust to variations of the system size. © 2013 Elsevier B.V. All rights reserved Daha fazlası Daha az

Autaptic pacemaker mediated propagation of weak rhythmic activity across small-world neuronal networks

Yılmaz, Ergin | Baysal, Veli | Özer, Mahmut | Perc, Matjaž

Article | 2016 | Physica A: Statistical Mechanics and its Applications444 , pp.538 - 546

We study the effects of an autapse, which is mathematically described as a self-feedback loop, on the propagation of weak, localized pacemaker activity across a Newman-Watts small-world network consisting of stochastic Hodgkin-Huxley neurons. We consider that only the pacemaker neuron, which is stimulated by a subthreshold periodic signal, has an electrical autapse that is characterized by a coupling strength and a delay time. We focus on the impact of the coupling strength, the network structure, the properties of the weak periodic stimulus, and the properties of the autapse on the transmission of localized pacemaker activity. Obta . . .ined results indicate the existence of optimal channel noise intensity for the propagation of the localized rhythm. Under optimal conditions, the autapse can significantly improve the propagation of pacemaker activity, but only for a specific range of the autaptic coupling strength. Moreover, the autaptic delay time has to be equal to the intrinsic oscillation period of the Hodgkin-Huxley neuron or its integer multiples. We analyze the inter-spike interval histogram and show that the autapse enhances or suppresses the propagation of the localized rhythm by increasing or decreasing the phase locking between the spiking of the pacemaker neuron and the weak periodic signal. In particular, when the autaptic delay time is equal to the intrinsic period of oscillations an optimal phase locking takes place, resulting in a dominant time scale of the spiking activity. We also investigate the effects of the network structure and the coupling strength on the propagation of pacemaker activity. We find that there exist an optimal coupling strength and an optimal network structure that together warrant an optimal propagation of the localized rhythm. © 2015 Elsevier B.V. All rights reserved Daha fazlası Daha az

Controlling the spontaneous spiking regularity via channel blocking on Newman-Watts networks of Hodgkin-Huxley neurons

Özer, Mahmut | Perc, Matjaž | Uzuntarla, Muhammet

Article | 2009 | EPL86 ( 4 ) , pp.538 - 546

We investigate the regularity of spontaneous spiking activity on Newman-Watts small-world networks consisting of biophysically realistic Hodgkin-Huxley neurons with a tunable intensity of intrinsic noise and fraction of blocked voltage-gated sodium and potassium ion channels embedded in neuronal membranes. We show that there exists an optimal fraction of shortcut links between physically distant neurons, as well as an optimal intensity of intrinsic noise, which warrant an optimally ordered spontaneous spiking activity. This doubly coherence resonance-like phenomenon depends significantly on, and can be controlled via, the fraction o . . .f closed sodium and potassium ion channels, whereby the impacts can be understood via the analysis of the firing rate function as well as the deterministic system dynamics. Potential biological implications of our findings for information propagation across neural networks are also discussed. © EPLA, 2009 Daha fazlası Daha az

Estimation of the propagation of flexural waves in thin plates using a single low-cost sensor

Onur, Tuğba Özge | Carlson, Johan E | Svanström, Erika | Hacıoğlu, Rıfat

Article | 2019 | Iranian Journal of Science and Technology - Transactions of Electrical Engineering43 ( 3 ) , pp.405 - 413

This paper demonstrates how flexural wave propagation in a thin plate can be modeled by estimating the combined effect of the excitation source signal and the impulse response of the ultrasonic sensor. The wave propagation in the plate is modeled using the wave equation for the flexural wave mode. A theoretical model for flexural wave propagation in thin plates has been derived, and it has been compared with measurements excited by tapping gently on the surface. The combined effects of the excitation source signal and the impulse response of the low-cost piezoelectric sensor are modeled using finite-impulse response and/or infinite- . . .impulse response filters. Thereafter, the performances of the selected filters are compared on estimating the wave propagation in a thin quartz glass plate. Results indicate that the most accurate estimation of wave propagation has been obtained using a linear phase filter which attributes all dispersions to the flexural wave. © 2018, Shiraz University Daha fazlası Daha az

Impact of network activity on noise delayed spiking for a Hodgkin-Huxley model

Özer, Mahmut | Graham, Lyle J.

Article | 2008 | European Physical Journal B61 ( 4 ) , pp.499 - 503

https://dx.doi.org/10.1140/epjb/e2008-00095-y https://hdl.handle.net/20.500.12628/6161

Enhancement of pacemaker induced stochastic resonance by an autapse in a scale-free neuronal network

Yılmaz, Ergin | Baysal, Veli | Perc, Matjaž | Özer, Mahmut

Article | 2016 | Science China Technological Sciences59 ( 3 ) , pp.364 - 370

An autapse is an unusual synapse that occurs between the axon and the soma of the same neuron. Mathematically, it can be described as a self-delayed feedback loop that is defined by a specific time-delay and the so-called autaptic coupling strength. Recently, the role and function of autapses within the nervous system has been studied extensively. Here, we extend the scope of theoretical research by investigating the effects of an autapse on the transmission of a weak localized pacemaker activity in a scale-free neuronal network. Our results reveal that by mediating the spiking activity of the pacemaker neuron, an autapse increases . . .the propagation of its rhythm across the whole network, if only the autaptic time delay and the autaptic coupling strength are properly adjusted. We show that the autapse-induced enhancement of the transmission of pacemaker activity occurs only when the autaptic time delay is close to an integer multiple of the intrinsic oscillation time of the neurons that form the network. In particular, we demonstrate the emergence of multiple resonances involving the weak signal, the intrinsic oscillations, and the time scale that is dictated by the autapse. Interestingly, we also show that the enhancement of the pacemaker rhythm across the network is the strongest if the degree of the pacemaker neuron is lowest. This is because the dissipation of the localized rhythm is contained to the few directly linked neurons, and only afterwards, through the secondary neurons, it propagates further. If the pacemaker neuron has a high degree, then its rhythm is simply too weak to excite all the neighboring neurons, and propagation therefore fails. © 2016, Science China Press and Springer-Verlag Berlin Heidelberg Daha fazlası Daha az

Effects of dynamic synapses on noise-delayed response latency of a single neuron

Uzuntarla, Muhammet | Özer, Mahmut | İleri, Uğur | Çalım, Ali | Torres, Joaquin J.

Article | 2015 | Physical Review E - Statistical, Nonlinear, and Soft Matter Physics92 ( 6 ) , pp.364 - 370

The noise-delayed decay (NDD) phenomenon emerges when the first-spike latency of a periodically forced stochastic neuron exhibits a maximum for a particular range of noise intensity. Here, we investigate the latency response dynamics of a single Hodgkin-Huxley neuron that is subject to both a suprathreshold periodic stimulus and a background activity arriving through dynamic synapses. We study the first-spike latency response as a function of the presynaptic firing rate f. This constitutes a more realistic scenario than previous works, since f provides a suitable biophysically realistic parameter to control the level of activity in . . .actual neural systems. We first report on the emergence of classical NDD behavior as a function of f for the limit of static synapses. Second, we show that when short-term depression and facilitation mechanisms are included at the synapses, different NDD features can be found due to their modulatory effect on synaptic current fluctuations. For example, an intriguing double NDD (DNDD) behavior occurs for different sets of relevant synaptic parameters. Moreover, depending on the balance between synaptic depression and synaptic facilitation, single NDD or DNDD can prevail, in such a way that synaptic facilitation favors the emergence of DNDD whereas synaptic depression favors the existence of single NDD. Here we report the existence of the DNDD effect in the response latency dynamics of a neuron. © 2015 American Physical Society Daha fazlası Daha az

Epileptic seizure detection using probability distribution based on equal frequency discretization

Orhan, Umut | Hekim, Mahmut | Özer, Mahmut

Article | 2012 | Journal of Medical Systems36 ( 4 ) , pp.2219 - 2224

In this study, we offered a new feature extraction approach called probability distribution based on equal frequency discretization (EFD) to be used in the detection of epileptic seizure from electroencephalogram (EEG) signals. Here, after EEG signals were discretized by using EFD method, the probability densities of the signals were computed according to the number of data points in each interval. Two different probability density functions were defined by means of the polynomial curve fitting for the subjects without epileptic seizure and the subjects with epileptic seizure, and then when using the mean square error criterion for . . .these two functions, the success of epileptic seizure detection was 96.72%. In addition, when the probability densities of EEG segments were used as the inputs of a multilayer perceptron neural network (MLPNN) model, the success of epileptic seizure detection was 99.23%. This results show that non-linear classifiers can easily detect the epileptic seizures from EEG signals by means of probability distribution based on EFD. © 2011 Springer Science+Business Media, LLC Daha fazlası Daha az

Optimization of digital holographic setup by a fuzzy logic prediction system

Kaya, Gülhan Ustabaş | Erkaymaz, Okan | Saraç, Zehra

Article | 2016 | Expert Systems with Applications56 , pp.177 - 185

In this study, the optimization of the digital holography setup is achieved by a using fuzzy logic prediction system. In fact, when this optimization process is experimentally performed, some parameters are changed in the setup. These parameters affect directly the obtained image quality after a reconstruction process, which is determined by normalized root mean square. The aim of this study is to achieve the optimization of digital holographic setup by using both experimental and fuzzy logic prediction systems. Furthermore, the required time during the experimental optimization can be lowered by using a numerical method like the fu . . .zzy logic prediction system. Here, the experimental optimization results and the optimization results obtained by the fuzzy logic prediction system are compared. It is offered that the designed experimental system can be optimized by using an artificial intelligent tool. The applied fuzzy logic prediction model is used the first time for optimization of hologram recording setup. As a result, it is reached a conclusion that the optimization of digital holographic setup can be numerically performed by the fuzzy logic prediction system. Moreover, while digital holographic setup is experimentally designed, the required time for optimization is reduced, as well. © 2016 Elsevier Ltd. All rights reserved Daha fazlası Daha az

A new adaptive neuro-fuzzy solution for optimization of the parameters in the digital holography setup

Ustabaş, Kaya Gülhan | Erkaymaz, Okan | Saraç, Zehra

Article | 2019 | Soft Computing23 ( 18 ) , pp.8827 - 8837

In this paper,a fuzzy interference and an adaptive neuro-fuzzy interference system models have been presented in order to accelerate designing of the digital holographic setup without experiment. The setting parameters of experimental holographic setup, which affect the quality of images obtained from reconstructed holograms, are predicted digitally by proposed models before the recording process. Hence, we reduce the required time for designing of digital holographic setup with optimization process. The adaptive neuro-fuzzy interference system model for the optimization of the digital holographic setup is first attempt in the liter . . .ature. The accuracy of the proposed models is examined by comparing the presented models and actual calculated experimental root-mean-square values. As a result, the accuracy of the adaptive neuro-fuzzy interference system shows the better performance than the fuzzy interference system. Moreover, the design of experimental setup can be occurred numerically in a short time by using adaptive neuro-fuzzy interference system models. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature Daha fazlası Daha az

Noise-delayed decay in the response of a scale-free neuronal network

Uzuntarla, Muhammet | Uzun, Rukiye | Yılmaz, Ergin | Özer, Mahmut | Perc, Matjaž

Article | 2013 | Chaos, Solitons and Fractals56 , pp.202 - 208

Noise-delayed decay occurs when the first-spike latency of a periodically forced neuron exhibits a maximum at particular noise intensity. Here we investigate this phenomenon at the network level, in particular by considering scale-free neuronal networks, and under the realistic assumption of noise being due to the stochastic nature of voltage-gated ion channels that are embedded in the neuronal membranes. We show that noise-delayed decay can be observed at the network level, but only if the synaptic coupling strength between the neurons is weak. In case of strong coupling or in a highly interconnected population the phenomenon vanis . . .hes, thus indicating that delays in signal detection can no longer be resonantly prolonged by noise. We also find that potassium channel noise plays a more dominant role in the occurrence of noise-delayed decay than sodium channel noise, and that poisoning the neuronal membranes may weakens or intensify the phenomenon depending on targeting. © 2013 Elsevier Ltd. All rights reserved Daha fazlası Daha az

Effect of the sub-threshold periodic current forcing on the regularity and the synchronization of neuronal spiking activity

Özer, Mahmut | Uzuntarla, Muhammet | Ağaoğlu, Şükrüye Nihal

Article | 2006 | Physics Letters, Section A: General, Atomic and Solid State Physics360 ( 1 ) , pp.135 - 140

We first investigate the amplitude effect of the subthreshold periodic forcing on the regularity of the spiking events by using the coefficient of variation of interspike intervals. We show that the resonance effect in the coefficient of variation, which is dependent on the driving frequency for larger membrane patch sizes, disappears when the amplitude of the subthreshold forcing is decreased. Then, we demonstrate that the timings of the spiking events of a noisy and periodically driven neuron concentrate on a specific phase of the stimulus. We also show that increasing the intensity of the noise causes the phase probability densit . . .y of the spiking events to get smaller values, and eliminates differences in the phase locking behavior of the neuron for different patch sizes. © 2006 Elsevier B.V. All rights reserved Daha fazlası Daha az

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