Arkin, Ali Hakan | Hazer, Baki | Adamus, Grazyna | Kowalczuk, Marek | Jedlinski, Zbigniew | Lenz, Robert W.

Editorial | 2001 | BIOMACROMOLECULES2 ( 3 ) , pp.623 - 627

Synthesis of an a,beta-alkyl branched polyester, i.e., poly(2-methyl-3-hydroxyoctanoate), has been accomplished via anionic polymerization of alpha-methyl-beta-pentyl-beta-propiolactone mediated by supramolecular complexes of potassium methoxide or potassium hydroxide, respectively. The structure of resulting polymers has been established by electrospray ionization multistage mass spectrometry (ESI-MSn), FT-IR, NMR, and GPC analyses. Previously proposed addition-elimination mechanism of the polymerization of beta-lactones containing alpha-hydrogen by alkoxide anion has been confirmed to operate also in the case of beta-lactone havin . . .g alkyl substituents in both alpha and beta positions Daha fazlası Daha az

Hazer, Baki

Review | 2010 | International Journal of Polymer Science2010 , pp.623 - 627

Poly(3-hydroxy alkanoate)s, PHAs, have been very attractive as biomaterials due to their biodegradability and biocompatibility. These hydrophobic natural polyesters, PHAs, need to have hydrophilic character particularly for drug delivery systems. In this manner, poly(ethylene glycol) (PEG) and hydrophilic functional groups such as amine, hydroxyl, carboxyl, and sulfonic acid have been introduced into the PHAs in order to obtain amphiphilic polymers. This review involves in the synthesis and characterization of the amphiphilic PHAs. Copyright © 2010 Baki Hazer.