Filtreler
Simulation of Parkinsonian Basal nuclei with network motifs

Çalım, Ali | Özer, Mahmut | Uzuntarla, Muhammet

Proceedings | 2017 | 2017 25th Signal Processing and Communications Applications Conference, SIU 2017

Nowadays, neurodegenerative diseases which affect human life quite negatively with motor, cognitive and psychiatric disorders are becoming widespread. One of the most common neurodegenerative disorder is Parkinson's disease. Recent electrophysiological experiments have shown that Basal Ganglia, a special region in the midbrain, is related to Parkinsonism. Beta frequency oscillations, which are important symptoms of Parkinson's disease, emerge intensively in Globus Pallidus and Subtalamus nuclei. In this study, anatomical connections of Globus Pallidus and Subtalamus are constructed computationally, and the cellular properties that g . . .ive rise to emergence of beta oscillations are investigated. © 2017 IEEE Daha fazlası Daha az

Effects of synaptic time delay on vibrational resonance in neuronal networks

Ağaoğlu, Şükrüye Nihal | Özer, Mahmut | Çalım, Ali | Uzuntarla, Muhammet

Proceedings | 2017 | 2017 25th Signal Processing and Communications Applications Conference, SIU 2017

In the phenomenon of vibrational resonance, the excitable system is under the influence of two periodic forces: a low-frequency (signal), a high-frequency (carrier). In this study, the effects of synaptic time delay on the vibrational resonance were investigated in two coupled FitzHugh-Nagumo neurons with electrical or chemical coupling. It is seen that, for both types of coupling by appropriate choice of synaptic time delay can be had a curative effect to transmission between two neurons at certain values of synaptic conductivity. © 2017 IEEE.

Effects of subthreshold excitation characteristics on vibrational resonance in weighted scale-free network

Ağaoğlu, Şükrüye Nihal | Özer, Mahmut | Çalım, Ali | Uzuntarla, Muhammet

Proceedings | 2017 | 2017 25th Signal Processing and Communications Applications Conference, SIU 2017

In this paper, the phenomena of Vibrational Resonance is investigated in an excitable system which consists of FitzHugh-Nagumo neurons with electrical coupling. Weak signal detection performance of excitable system is examined in scale-free network (unweighted or weighted) topology. The simulation results show that; weighting the scale-free network, average connectivity degree, amplitude and frequency of weak signal play an active role to determine the data carrying performance of neurons based on Vibrational Resonance. It is determined that, the amount of required energy for creating resonance peaks of excitable system is decreased . . . significantly by choosing the correct value of weight control parameter in a weighted network especially. © 2017 IEEE Daha fazlası Daha az

Synchronization induced termination in neuronal networks

Çalım, Ali | Ağaoğlu, Şükriye Nihal | Uzuntarla, Muhammet

Proceedings | 2017 | 2017 25th Signal Processing and Communications Applications Conference, SIU 2017

Vital functions which take place in the brain are accomplished through synchronized neural activities between interconnected neuronal populations. In healthy and unhealthy nerve system, rhythms in different frequencies can be recognized as they are responsible for neural synchronization. Despite this, in the case of global synchronization where oscillation power is the maximum, as observed in epileptic seizures, neural activity can terminate. In this study, effects of neural network characteristics synchronization emerges from on activity termination are computationally investigated. Stochastic Hodgkin-Huxley (H-H) equations are use . . .d in the simulations. The results show that synchronization increases when neurons have high synaptic conductance and due to this, strong synaptic current neurons exposed to terminates the firings. © 2017 IEEE Daha fazlası Daha az

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