A computer software for simulating single-compartmental model of neurons

Özer, Mahmut | İşler, Yalçın | Özer, Halil

Article | 2004 | Computer Methods and Programs in Biomedicine75 ( 1 ) , pp.51 - 57

In this paper, a new computer software package, Yalzer, is introduced for simulating single-compartmental model of neurons. Passive or excitable membranes with voltage-gated ion channels can be modeled, and current clamp and voltage clamp experiments can be simulated. In the Yalzer, first-order differential equations used to define the dynamics of the gate variables and the membrane potential are solved by two separate integration methods with variable time steps: forward Euler and exponential Euler methods. Outputs of the simulation are shown on a spreadsheet template for allowing flexible data manipulation and can be graphically d . . .isplayed. The user can define the model in detail, and examine the excitability of the model and the dynamics of voltage-gated ion channels. The software package addresses to ones who want to run simple simulations of neurons without need to any programming language skills or expensive software. It can also be used for educational purposes. © 2003 Elsevier Ireland Ltd. All rights reserved Daha fazlası Daha az

ZnO applications and challenges

Oprea, Ovidiu | Andronescu, Ecaterina | Ficai, Denisa | Ficai, Anton | Oktar, Faik N | Yetmez, Mehmet

Article | 2014 | Current Organic Chemistry18 ( 2 ) , pp.192 - 203

Metal oxide nanoparticles represent a new class of important materials that are increasingly being developed for use in research and health-related applications. Although the in vitro antibacterial activity of zinc oxides and some other zinc compounds has been known for quite some time, only in the last few years nanoparticles of ZnO have been investigated for their antibacterial activity, the knowledge about it remaining deficient. The antimicrobial activity of ZnO nanoparticles is strongly influenced by some factors such as size and the presence of light. The potential applications include, but are not limited to, topic drugs, cos . . .metics or component for agents that control the spread of bacterial strains (antibacterial paint in hospitals, antibacterial coatings for fabrics, antibacterial packaging for food, etc). The current review aims to present the level of knowledge accumulated on the antibacterial and antifungal activity of ZnO. © 2014 Bentham Science Publishers Daha fazlası Daha az

New design for an adjustable cise space maintainer

Özkalaycı, Nurhat | Yetmez, Mehmet

Article | 2018 | BioMed Research International2018 , pp.192 - 203

Objective. The aim of this study is to present a new adjustable Cise space maintainer for preventive orthodontic applications. Methods. Stainless steel based new design consists of six main components. In order to understand the major displacement and stress fields, structural analysis for the design is considered by using finite element method. Results. Similar to major displacement at y-axis, critical stresses ?x and ?xy possess a linear distribution with constant increasing. Additionally, strain energy density (SED) plays an important role to determine critical biting load capacity. Conclusion. Structural analysis shows that the . . .space maintainer is stable and is used for maintaining and/or regaining the space which arouses early loss of molar tooth. © 2018 Nurhat Ozkalayci and Mehmet Yetmez Daha fazlası Daha az

Studies on characterization of bovine hydroxyapatite/CaTiO3 biocomposites

Öztürk, Suat | Yetmez, Mehmet

Article | 2016 | Advances in Materials Science and Engineering2016 , pp.192 - 203

Sintering effects and mechanical properties of bovine hydroxyapatite/CaTiO3 composites are investigated for different CaTiO3 ratios. Results indicate that densities of the biocomposites increase while total porosities of those decrease with increasing sintering temperature. Moreover, modulus of elasticity and microhardness increase with increasing sintering temperature. However, values of both toughness and fracture toughness of the biocomposites generally rise with increasing sintering temperature except for 1300°C. © 2016 Suat Ozturk and Mehmet Yetmez.

Sintering behavior and mechanical properties of biphasic calcium phosphate ceramics

Yetmez, Mehmet

Article | 2014 | Advances in Materials Science and Engineering2014 , pp.192 - 203

The sintering behavior and the mechanical properties of a mechanical mixture of hydroxyapatite and tricalcium phosphate (BCP) ceramics with the composition of 30% HA and 70% TCP are experimentally investigated in the temperature range between 1000°C and 1300°C. The results show that consolidation, grain growth, and Vickers hardness generally increase with increasing sintering temperature up to 1200°C. However, microstructure observation indicates that cracks are formed along the grain boundaries as well as in the bulk of the grains after sintering at 1200°C. Moreover, the best values of compressive strength, modulus of elasticity, a . . .nd toughness are achieved in the samples sintered at 1100°C. These properties at 1100°C decay with sintering at 1200°C and increase again after sintering at 1300°C. © 2014 Mehmet Yetmez Daha fazlası Daha az

A new appliance for improving the miniscrew stability

Özkalaycı, Nurhat | Yetmez, Mehmet

Article | 2016 | Advances in Materials Science and Engineering2016 , pp.192 - 203

The aim of this study is to present a new appliance called stability leg designed as an additional anchorage providing device for increasing primary stability of orthodontic miniscrew. For this purpose, two finite element models (FEMs) with two different cortical layer thicknesses of 1 mm and 2 mm are considered. In order to achieve the stability analysis, these two main models, namely, Model I and Model II, are divided into subgroups according to stability leg lengths. Two types of forces are considered. (1) First force is a constant force of 1 N which is applied to all two models. (2) Second force is defined in the range of 1-4 N. . . . Each of 1, 2.5, and 4 N of the second force is applied with a position angle ranging from 34° to 44°. Results show that stability of a miniscrew with 5 mm leg increases primary stability of the miniscrew. © 2016 Nurhat Ozkalayci and Mehmet Yetmez Daha fazlası Daha az

A new orthodontic appliance with a mini screw for upper molar distalization

Özkalaycı, Nurhat | Yetmez, Mehmet

Article | 2016 | Applied Bionics and Biomechanics2016 , pp.192 - 203

The aim of this study is to present a new upper molar distalization appliance called Cise distalizer designed as intraoral device supported with orthodontic mini screw for upper permanent molar distalization. The new appliance consists of eight main components. In order to understand the optimum force level, the appliance under static loading is tested by using strain gage measurement techniques. Results show that one of the open coils produces approximately 300 gr distalization force. Cise distalizer can provide totally 600 gr distalization force. This range of force level is enough for distalization of upper first and second molar . . . teeth. © 2016 Nurhat Ozkalayci and Mehmet Yetmez Daha fazlası Daha az

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