Özer, Mahmut | İşler, Yalçın | Özer, Halil

Article | 2004 | Computer Methods and Programs in Biomedicine75 ( 1 ) , pp.51 - 57

In this paper, a new computer software package, Yalzer, is introduced for simulating single-compartmental model of neurons. Passive or excitable membranes with voltage-gated ion channels can be modeled, and current clamp and voltage clamp experiments can be simulated. In the Yalzer, first-order differential equations used to define the dynamics of the gate variables and the membrane potential are solved by two separate integration methods with variable time steps: forward Euler and exponential Euler methods. Outputs of the simulation are shown on a spreadsheet template for allowing flexible data manipulation and can be graphically d . . .isplayed. The user can define the model in detail, and examine the excitability of the model and the dynamics of voltage-gated ion channels. The software package addresses to ones who want to run simple simulations of neurons without need to any programming language skills or expensive software. It can also be used for educational purposes. © 2003 Elsevier Ireland Ltd. All rights reserved Daha fazlası Daha az

Oprea, Ovidiu | Andronescu, Ecaterina | Ficai, Denisa | Ficai, Anton | Oktar, Faik N | Yetmez, Mehmet

Article | 2014 | Current Organic Chemistry18 ( 2 ) , pp.192 - 203

Metal oxide nanoparticles represent a new class of important materials that are increasingly being developed for use in research and health-related applications. Although the in vitro antibacterial activity of zinc oxides and some other zinc compounds has been known for quite some time, only in the last few years nanoparticles of ZnO have been investigated for their antibacterial activity, the knowledge about it remaining deficient. The antimicrobial activity of ZnO nanoparticles is strongly influenced by some factors such as size and the presence of light. The potential applications include, but are not limited to, topic drugs, cos . . .metics or component for agents that control the spread of bacterial strains (antibacterial paint in hospitals, antibacterial coatings for fabrics, antibacterial packaging for food, etc). The current review aims to present the level of knowledge accumulated on the antibacterial and antifungal activity of ZnO. © 2014 Bentham Science Publishers Daha fazlası Daha az

Özkalaycı, Nurhat | Yetmez, Mehmet

Article | 2018 | BioMed Research International2018 , pp.192 - 203

Objective. The aim of this study is to present a new adjustable Cise space maintainer for preventive orthodontic applications. Methods. Stainless steel based new design consists of six main components. In order to understand the major displacement and stress fields, structural analysis for the design is considered by using finite element method. Results. Similar to major displacement at y-axis, critical stresses ?x and ?xy possess a linear distribution with constant increasing. Additionally, strain energy density (SED) plays an important role to determine critical biting load capacity. Conclusion. Structural analysis shows that the . . .space maintainer is stable and is used for maintaining and/or regaining the space which arouses early loss of molar tooth. © 2018 Nurhat Ozkalayci and Mehmet Yetmez Daha fazlası Daha az

Öztürk, Suat | Yetmez, Mehmet

Article | 2016 | Advances in Materials Science and Engineering2016 , pp.192 - 203

Sintering effects and mechanical properties of bovine hydroxyapatite/CaTiO3 composites are investigated for different CaTiO3 ratios. Results indicate that densities of the biocomposites increase while total porosities of those decrease with increasing sintering temperature. Moreover, modulus of elasticity and microhardness increase with increasing sintering temperature. However, values of both toughness and fracture toughness of the biocomposites generally rise with increasing sintering temperature except for 1300°C. © 2016 Suat Ozturk and Mehmet Yetmez.

Yetmez, Mehmet

Article | 2014 | Advances in Materials Science and Engineering2014 , pp.192 - 203

The sintering behavior and the mechanical properties of a mechanical mixture of hydroxyapatite and tricalcium phosphate (BCP) ceramics with the composition of 30% HA and 70% TCP are experimentally investigated in the temperature range between 1000°C and 1300°C. The results show that consolidation, grain growth, and Vickers hardness generally increase with increasing sintering temperature up to 1200°C. However, microstructure observation indicates that cracks are formed along the grain boundaries as well as in the bulk of the grains after sintering at 1200°C. Moreover, the best values of compressive strength, modulus of elasticity, a . . .nd toughness are achieved in the samples sintered at 1100°C. These properties at 1100°C decay with sintering at 1200°C and increase again after sintering at 1300°C. © 2014 Mehmet Yetmez Daha fazlası Daha az

Karabağlı, Gamze | Düzgün, Oktay | Karabağlı, Murat | Haktanır, Damla | Gürel, Aydın | Yetmez, Mehmet

Article | 2015 | Ankara Üniversitesi Veteriner Fakültesi Dergisi62 ( 3 ) , pp.205 - 210

Tendo kopukları çoğunlukla ekstremitelerin distal kısımlarında meydana gelmekte ve uzun süreli bir iyileşme periyodu gerektirmektedir. Travmatik aşil tendo kopuklarında operasyon öncesi ve sonrasını da kapsayan 6 -8 haftalık bir bandaj uygulaması ile hareketsizlik sağlanmaktadır. Bu uygulamanın neden olacağı diğer ortopedik problemleri önlemek ve iyileşme periyodunu hızlandırabilmek amacıyla, operasyon sonrası lokal uygulamalar yapılmaktadır. Ultrason terapi (TUS) bunlardan biridir. Fonofo rezis ise emilim ö zelliği olan ilaçların TUS eşliğinde lokal olarak bölgeye emdirilmesidir. Deneysel çalışmamızda 40 adet erkek, 1 yaşında, orta . . .lama 3 kg ağırlığında, Yeni Zelanda tavşanı kullanıldı. Tavşanlar 4 gruba ayrıldı ve tüm tavşanların her iki arka bacağında deneysel Aşil tendo rupturu oluşturuldu ve hemen akabinde tenorafi ile onarıldı. Birinci ve üçüncü gruptaki tavşanların sağ bacaklarına operasyondan sonraki 10 gün boyunca ultrason terapi uygulandı. İkinci ve dördüncü gruptaki tavşanların sağ bacaklarına ise ope rasyondan sonraki 10 gün boyunca fonoforez uygulandı. Tüm çalışma gruplarında, sol bacaklar kontrol grubunu oluşturdu. Tavşanlar 30. gün sonunda ötenazi edilerek grup 1 ve 2’deki örnekler histopatolojik olarak, grup 3 ve 4’teki örnekler ise biyomekanik olarak incelendi. Biyomekanik inceleme için tendoların kopma noktaları N (Newton) cinsinden karşılaştırıldı. Çalışmanın sonucunda; ultrason terapinin fonoforezle karşılaştırıldığında tendo iyileşmesi için daha üstün bir metod olduğu kanısına varıldı. Tendon ruptures occur generally at distal portions of extremities and require relatively long recovery period. Traumatic ruptures of Achilles tendon need 6 -8 weeks of immobility period including pre and postoperative days. In order to avoid other orthopedical problems by this application and to speed up the reco very period, postoperative local administrations are done. Therapeutic Ultrasound (TUS) is one of these applications. Phonophoresis is the local absorbing procedure of some drugs by me ans of TUS which is applied to the affected area. Forty male New Zealand rabbits were used in the study which were one year old and mean 3 kg body -weight. The rabbits were divided into 4 groups and experimental Achilles tendon rupture was created in both legs of all rabbits and repaired immediately by tenorrhaphy. The right le gs of rabbits of groups 1 and 3 were treated postoperatively with TUS for 10 days. The right legs of rabbits in groups 2 and 4 were treated postoperatively with phonophoresis for 10 days. Left legs of all rabbits served as the control group. All rabbits we re euthanized at the end of the 30th day. Samples which were taken from groups 1 and 2 were examined histopathologically and those in groups 3 and 4 were examined biomechanically. In biomechanical investigations, the rupture points of the tendons in N (Newton) were compared. At the end of the study, it was concluded that TUS is a superior for tendon healing when compared to phonophoresis Daha fazlası Daha az

Özkalaycı, Nurhat | Yetmez, Mehmet

Article | 2017 | 7tepe Klinik13 ( 1 ) , pp.13 - 16

Amaç: Çalışmanın amacı ortodontik yüz maskesi kullanım süresi ve düzenini takip etmek amacıyla yüz maskesinin alın kısmına takılan yeni bir izleme sisteminin sunulması ve değerlendirilmesidir.Gereç ve Yöntem: Yeni izleme sistemi ana gövde, yuva kapağı ve sensör olmak üzere 3 ana parçadan oluşmaktadır. Ana gövde iki adet yan sabitleyici, bir adet orta sabitleyici, sensör takma yuvası ve sekiz vida deliğinden oluşmaktadır. Ana gövdedeki tüm parçaların yerleştirilmesini takiben sensör programlanmış ve yuvaya yerleştirilmiştir daha sonra kapak sabitlenmiştir. Sistem laboratuvar koşullarında test edilmiştir.Bulgular: Çalışma sonunda elde . . . edilen verinin detaylı analizi göstermiştir ki izleme sistemi takma ve sökme süreçlerini doğru bir şekilde takip etmektedir. Yeni tipteki ortodontik yüz maskesi takma sürelerini ve düzenini izleyebilmektedir. Sonuç: Yüz maskesi tedavisi sagital yöndeki üst çene yetersizliğinin düzeltilmesinde elzemdir. Toplam kullanım süresi ve düzenli kullanım ortodontik ve ortopedik tedavinin başarısını etkileyen temel faktörlerdir. Objektif ve bilimsel olarak bu sürecin izlenmesi bu meşakkatli, uzun ve pahalı tedavide klinisyenlere büyük katkı sağlayacaktır. Bu çalışmanın sonucu göstermiştir ki yeni izleme sistemi yüz maskesi kullanımı için uygundur. Introduction: The aim of this study is to present and evaluate a new monitoring system attached to forehead part of face mask for tracking orthodontic face mask usage time and regularity. Methods: The new monitoring system consists of three main parts as main body, slot cover and sensor. The main body includes two lateral fixer, a median fixer, sensor insertion slot and eight screw holes. After completing the assembly procedure for the main part, the sensor is programmed and inserted to its slot and then the cover is screwed. The system was tested under laboratory condition.Results: Detailed analysis of the post study data showed that the system measured the attachment and detachment period correctly. The new type orthodontic face mask can monitor the wearing time and regularity.Conclusion: Face mask therapy is a crucial for correction of sagittal maxillary deficiency. Total wearing time and regularity is main factors to reach to a success level of this orthodontic and orthopedic treatment. Objective and scientific monitoring system proposed here may help the clinicians for difficult, long and expensive treatment. Conclusion of present study show that the system proposed is suitable for the further face mask usage Daha fazlası Daha az

Karabağlı, Gamze | Düzgün, Oktay | Karabağlı, Murat | Haktanır, Damla | Gürel, Aydın | Yetmez, Mehmet

Article | 2015 | ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI62 ( 3 ) , pp.205 - 210

Tendon ruptures occur generally at distal portions of extremities and require relatively long recovery period. Traumatic ruptures of Achilles tendon need 6-8 weeks of immobility period including pre and postoperative days. In order to avoid other orthopedical problems by this application and to speed up the recovery period, postoperative local administrations are done. Therapeutic Ultrasound (TUS) is one of these applications. Phonophoresis is the local absorbing procedure of some drugs by means of TUS which is applied to the affected area. Forty male New Zealand rabbits were used in the study which were one year old and mean 3 kg b . . .ody-weight. The rabbits were divided into 4 groups and experimental Achilles tendon rupture was created in both legs of all rabbits and repaired immediately by tenorrhaphy. The right legs of rabbits of groups 1 and 3 were treated postoperatively with TUS for 10 days. The right legs of rabbits in groups 2 and 4 were treated postoperatively with phonophoresis for 10 days. Left legs of all rabbits served as the control group. All rabbits were euthanized at the end of the 30th day. Samples which were taken from groups 1 and 2 were examined histopathologically and those in groups 3 and 4 were examined biomechanically. In biomechanical investigations, the rupture points of the tendons in N (Newton) were compared. At the end of the study, it was concluded that TUS is a superior for tendon healing when compared to phonophoresis Daha fazlası Daha az

Özkalaycı, Nurhat | Yetmez, Mehmet

Article | 2016 | Advances in Materials Science and Engineering2016 , pp.205 - 210

The aim of this study is to present a new appliance called stability leg designed as an additional anchorage providing device for increasing primary stability of orthodontic miniscrew. For this purpose, two finite element models (FEMs) with two different cortical layer thicknesses of 1 mm and 2 mm are considered. In order to achieve the stability analysis, these two main models, namely, Model I and Model II, are divided into subgroups according to stability leg lengths. Two types of forces are considered. (1) First force is a constant force of 1 N which is applied to all two models. (2) Second force is defined in the range of 1-4 N. . . . Each of 1, 2.5, and 4 N of the second force is applied with a position angle ranging from 34° to 44°. Results show that stability of a miniscrew with 5 mm leg increases primary stability of the miniscrew. © 2016 Nurhat Ozkalayci and Mehmet Yetmez Daha fazlası Daha az

Özkalaycı, Nurhat | Yetmez, Mehmet

Article | 2016 | Applied Bionics and Biomechanics2016 , pp.205 - 210

The aim of this study is to present a new upper molar distalization appliance called Cise distalizer designed as intraoral device supported with orthodontic mini screw for upper permanent molar distalization. The new appliance consists of eight main components. In order to understand the optimum force level, the appliance under static loading is tested by using strain gage measurement techniques. Results show that one of the open coils produces approximately 300 gr distalization force. Cise distalizer can provide totally 600 gr distalization force. This range of force level is enough for distalization of upper first and second molar . . . teeth. © 2016 Nurhat Ozkalayci and Mehmet Yetmez Daha fazlası Daha az