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Eye injuries at a tertiary health center in the west Black Sea region, Turkey

Alpay, Atilla | Ozcan, Ozlem | Ugurbas, Silay Canturk | Ugurbas, Suat Hayri

Article | 2012 | ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY18 ( 2 ) , pp.118 - 124

BACKGROUND We aimed to investigate the clinical aspects and visual prognosis in eye injury and to constitute data in the west Black Sea region in Turkey for national statistics. METHODS A retrospective analysis of 281 eye trauma cases admitted to the Emergency Department of Zonguldak Karaelmas University Hospital between 2005 and 2010 was performed. RESULTS A majority of eye injuries (42.7%) affected individuals aged 30 to 50 years. The most frequent cause of injury in the rural areas was wooden objects. The most frequent cause of injury in males aged 30 to 50 years was work-site injuries. Corneal-scleral lacerations were found to b . . .e the most serious injuries with regard to initial and final visual acuities. CONCLUSION Eye injuries are still the most common and preventable cause of blindness. Simple precautions and public education might prevent this health problem, which causes economic and labor force loss and psychological problems. One of the basic precautions would be raising public awareness on wearing a seat belt inside the car and protective eyeglasses at the work site and while working in rural areas Daha fazlası Daha az

Prognostic value of serum procalcitonin and C-reactive protein levels in critically ill patients who developed ventilator-associated pneumonia

Tanriverdi H. | Tor M.M. | Kart L. | Altin R. | Atalay F. | Sumbsümbüloglu V.

Article | 2015 | Annals of Thoracic Medicine10 ( 2 ) , pp.137 - 142

INTRODUCTION: Ventilator-associated pneumonia (VAP) is an important cause of mortality and morbidity in critically ill patients. We sought to determine the prognostic value of procalcitonin (PCT) and C-reactive protein (CRP) kinetics in critically ill patients who developed VAP. METHODS: Patients who were admitted to the intensive care unit (ICU) and developed VAP were eligible. Patients were followed for 28 days after the pneumonia diagnosis and blood samples for PCT and CRP were collected on the day of the pneumonia diagnosis (D0), and days 3 (D3) and 7 (D7) after the diagnosis. Patients were grouped as survivors and non-survivors . . ., and the mean PCT and CRP values and their kinetics were assessed. RESULTS: In total, 45 patients were enrolled. Of them, 22 (48.8%) died before day 28 after the pneumonia diagnosis. There was no significant difference between the survivor and non-survivor groups in terms of PCT on the day of pneumonia diagnosis or CRP levels at any point. However, the PCT levels days 3 and 7 were significantly higher in the non-survivor group than the survivor group. Whereas PCT levels decreased significantly from D0 to D7 in the survivor group, CRP did not. A PCT level above 1 ng/mL on day 3 was the strongest predictor of mortality, with an odds ratio of 22.6. CONCLUSION: Serum PCT was found to be a superior prognostic marker compared to CRP in terms of predicting mortality in critically ill patients who developed VAP. The PCT level on D3 was the strongest predictor of mortality in VAP Daha fazlası Daha az

A simple discharge risk model for predicting 1-year mortality in hospitalised acute decompansated heart failure patients with reduced ejection fraction

Karauzum, Kurtulus | Karauzum, Irem | Ural, Dilek | Baydemir, Canan | Aktas, Mujdat | Celikyurt, Umut | Kozdag, Guliz

Article | 2018 | ACTA CARDIOLOGICA73 ( 2 ) , pp.164 - 170

Objective: The risk stratification for prognosis in heart failure is very important for optimal disease management and decision making. The aim of this study was to establish a simple discharge 1-year mortality prediction model by integrating data obtained from demographic characteristics, clinical evaluation, laboratory biomarkers and echocardiographic evaluation of hospitalised heart failure with reduced ejection fraction (HFrEF) patients with acute decompensation. Methods and results: A risk score model was developed based on beta-coefficient number of variables in a multivariable logistic regression model which was created with . . .the use of data on clinical, laboratory, imaging and therapeutic findings of 670 patients (65.4% males, 65 +/- 11 years) who was hospitalised with acute decompensated HFrEF. The mean left ventricular ejection fraction (LVEF) was 26 +/- 9%. Independent predictors of mortality were: age >= 75 years, sodium Daha fazlası Daha az

Does Type 2 Diabetes Mellitus Affect the Healing of Bell's Palsy in Adults?

Şevik Eliçora S. | Erdem D.

Article | 2018 | Canadian Journal of Diabetes42 ( 4 ) , pp.433 - 436

Objectives: Bell's palsy (BP) is defined as an acute facial weakness of unknown cause. Many factors affecting the healing of BP have been identified; 1 factor commonly considered relevant is the presence of type 2 diabetes mellitus. Our aim was to investigate the effects of diabetes on the healing of BP. Methods: Sixty patients with BP were followed up for 1 to 3 years and were divided into 2 groups, those with and those without type 2 diabetes. All were prescribed prednisone (initially 1 mg/kg per day, with a tapered dose reduction) and acyclovir (200 mg orally every 4 h, 5 times daily, for 5 days). Their recovery times were compar . . .ed. Results: The healing times of the patients with and without diabetes did not differ. Conclusions: Diabetes does not affect the severity, recovery rate from or healing of BP. © 2017 Diabetes CanadaObjectifs: La paralysie de Bell (PB) se caractérise par une faiblesse faciale soudaine dont la cause est inconnue. Parmi les nombreux facteurs qui nuisent à la guérison de la PB, le facteur généralement jugé pertinent est la présence du diabète sucré de type 2. Notre objectif était d'examiner les répercussions du diabète sur la guérison de la PB. Méthodes: Nous avons suivi 60 patients atteints de PB durant 1 à 3 ans et les avons répartis en 2 groupes : les patients atteints du diabète de type 2 et les patients non atteints. Tous se sont fait prescrire de la prednisone (ordonnance initiale de 1 mg/kg par jour, suivie d'une réduction progressive de la dose) et de l'acyclovir (200 mg par voie orale toutes les 4 heures, 5 fois par jour, durant 5 jours). Nous avons comparé leur vitesse de guérison. Résultats: La vitesse de guérison des patients diabétiques ou non diabétiques ne différait pas. Conclusions: Le diabète n'a pas de répercussions sur la gravité le taux de rétablissement ou la guérison de la PB Daha fazlası Daha az

Long-term prognostic value of stress-redistribution-reinjection Tl-201 imaging in patients with severe left ventricular dysfunction and coronary artery bypass surgery

Gursurer, M | Emre, AE | Gercekoglu, H | Uslubas, S | Aksoy, M | Ersek, B

Article | 2002 | INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING18 ( 2 ) , pp.125 - 133

Objectives: This study sought to evaluate the long-term prognostic significance of stress-redistribution-reinjection Tl-201 imaging in patients with severe left ventricular (LV) dysfunction and coronary artery bypass surgery. Background: Preoperative stress-redistribution-reinjection TI-201 imaging detects viable but asynergic segments which show functional improvement postoperatively and is considered as a valuable noninvasive method in selection of patients with severe LV dysfunction for revascularization. The long-term prognostic value of the reinjection technique remains unclear. Methods: Fifty-two patients with severe LV dysfun . . .ction (mean ejection fraction (EF) 0.32 +/- 0.03) who underwent coronary artery bypass surgery in 1993-1994 were included in the study. Patients had follow-up 49 :1: 12 months. LV function was assessed by two-dimensional echocardiography. Perfusion was assessed by TI-201 SPECT imaging and was graded on a four-point scale (0 = normal, 3 = absent uptake) using the 20 segment model. Perfusion index was derived by adding the score of all segments and dividing these by 20. Patients were divided into two groups. Group A comprised patients with seven and more dysfunctional viable myocardial segments. Group B included patients with less than seven dysfunctional but viable segments. Results: Mean EF increased from 0.32 +/- 0.03 to 0.46 +/- 0.04. Mean perfusion index did not show a significant difference as a whole during follow-up compared to the early postoperative values (0.9 +/- 0.4 and 1.1 +/- 0.4, p = NS). When adequacy of revascularization was considered, the predictive value of a positive preoperative viability test for functional improvement was 82%. Nineteen cardiac events occurred in group B patients and six in group A patients: six deaths (four from cardiac and two from noncardiac causes), 13 myocardial infarctions (MI). Multivariate Cox survival analysis identified the number of viable segments detected preoperatively (chi(2) = 7.2, p = 0.002), postoperative improvement in Tl-uptake (chi(2) = 6.6, p = 0.01) and functional improvement (chi(2) = 5.3, p = 0.03) postoperatively as independent predictors of cardiac events. Preoperative EF and functional capacity were not associated with cardiac events in long-term prognosis. Conclusion: These data suggest that preoperative stress-redistribution-reinjection TI-201 imaging, specifically the number of viable segments detected preoperatively and postoperative improvement in TI-201 uptake provide important long-term prognostic information in patients with severe LV dysfunction who had coronary artery bypass surgery Daha fazlası Daha az

Elevated levels of vitamin B12 in chronic stable heart failure: a marker for subclinical liver damage and impaired prognosis

Argan, Onur | Ural, Dilek | Karauzum, Kurtulus | Bozyel, Serdar | Aktas, Mujdat | Karauzum, Irem Yilmaz | Kozdag, Guliz

Article | 2018 | THERAPEUTICS AND CLINICAL RISK MANAGEMENT14 , pp.1067 - 1073

Background: Elevated vitamin B12 is a sign for liver damage, but its significance in chronic stable heart failure (HF) is less known. The present study investigated the clinical correlates and prognostic significance of vitamin B12 levels in stable systolic HF. Methods: A total of 129 consecutive patients with HF and 50 control subjects were enrolled. Data regarding demographics, clinical signs, therapeutic and conventional echocardiographic measurements were recorded for all patients. Right-sided HF was defined as the presence of at least one of the typical symptoms (ankle swelling) or specific signs (jugular venous distention or a . . .bdominojugular reflux) of right HF. Cox proportional hazards regression analyses were performed to determine the independent prognostic determinants of mortality. Results: Baseline B12 levels in HF patients (n=129) with and without right sided HF were significantly higher compared to healthy controls (n=50): Median 311 pg/mL and 235 pg/mL vs 198 pg/mL, respectively (P=0.005). Folic acid levels were similar between the study groups. Age, ejection fraction, left atrial size, estimated glomerular filtration rate, and direct and indirect bilirubin levels were significantly correlated to serum B12 level in univariate analysis. In multivariate analysis, independent correlates of B12 were direct bilirubin (R=0.51, P= 270 pg/mL had 80% sensitivity and 58% specificity for predicting all-cause mortality (area under the curve=0.672, 95% CI=0.562-0.781; P=0.003). However, in Cox regression analysis, only left atrial diameter, level of direct bilirubin, and the presence of abdominojugular reflux were independent predictors of death. Conclusion: Increased B12 in stable HF patients is associated with increased direct bilirubin due to right HF, indicating a cardiohepatic syndrome, but neither B12 nor folic acid are independently associated with mortality Daha fazlası Daha az

Neural cell adhesion molecule-180 expression as a prognostic criterion in colorectal carcinoma: Feasible or not?

Tascilar, Oge | Cakmak, Gueleniz Karadeniz | Tekin, Ishak Ozel | Emre, Ali Ugur | Ucan, Bulent Hamdi | Irkorucu, Oktay | Karakaya, Kemal

Article | 2007 | WORLD JOURNAL OF GASTROENTEROLOGY13 ( 41 ) , pp.5476 - 5480

AIM: To evaluate the frequency of neural cell adhesion molecule (NCAM)-180 expression in fresh tumor tissue samples and to discuss the prognostic value of NCAM-180 in routine clinical practice. METHODS: Twenty-six patients (16 men, 10 women) with colorectal cancer were included in the study. Fresh tumor tissue samples and macroscopically healthy proximal margins of each specimen were subjected to flow-cytometric analysis for NCAM-180 expression. RESULTS: Flow-cytometric analysis determined NCAM-180 expression in whole tissue samples of macroscopically healthy colorectal tissues. However, NCAM-180 expression was positive in only one . . .case (3.84%) with well-differentiated Stage II disease who experienced no active disease at 30 months follow-up. CONCLUSION: As a consequence of the limited number of cases in our series, it might not be possible to make a generalisation, nevertheless the routine use of NCAM-180 expression as a prognostic marker for colorectal carcinoma seems to be unfeasible and not cost-effective in clinical practice due to its very low incidence. (C) 2007 WJG. All rights reserved Daha fazlası Daha az

Hygroma colli cysticum: Prenatal diagnosis and prognosis

Tanriverdi, HA | Hendrik, HJ | Ertan, AK | Axt, R | Schmidt, W

Article | 2001 | AMERICAN JOURNAL OF PERINATOLOGY18 ( 8 ) , pp.415 - 420

The objective of this study is to analyze the prenatal management and prognostic factors of hygroma colli cysticum by using cytogenetic tests and sonographic morphological features. All cases with hygroma colli cysticum diagnosed and managed at our Prenatal Diagnostics Unit between January 96 and September 2000 were analyzed. Sonographic morphological features were divided in two groups; nonseptated (n = 18) and septated (n = 12) hygroma colli cysticum lesions were compared with fetal karyotype results and pregnancy outcome data. Statistical analysis was performed by Chi-square test and statistical significance was defined as p < 0. . . .05. In 5 years, 30 cases with hygroma colli cysticum were identified. Cytogenetic results were obtained from 23 (76.7%) cases (four chorionic villus sampling and 19 amniocentesis). Chromosomal abnormalities were present in 13 cases (56.5%). The most common chromosomal abnormality was Turner Syndrome (four cases, 17.4%) and Trisomy 18 (four cases, 17.4%). Pregnancy outcome data were available for 29 patients. Those fetuses with septated hygroma colli cysticum tended to have a worse fetal outcome, without statistical significance (p > 0.05), compared with the nonseptated hygroma colli cysticum cases (75 vs. 61.1%, respectively). Fetal hygroma colli cysticum, either septated or not, carries high risks of aneuploidies and adverse fetal outcome. Recommended management includes karyotyping and if parents decide to continue the pregnancy ultrasound scan at 20 to 22 weeks' gestation is necessary, for excluding associated anomalies. At birth, if the cystic hygroma persists, it should be noted that a respiratory difficulty can happen and a pediatrician should standby as a precaution Daha fazlası Daha az

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