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Primary thyroid lymphoma arising in the setting of Hashimoto's thyroiditis

Dogan Gün B. | Gün M.O. | Karamanoglu Z.

Article | 2004 | Turkish Journal of Medical Sciences34 ( 6 ) , pp.395 - 398

[No abstract available]

Chronic lymphocytic thyroiditis and tumor-infiltrating lymphocytes combined in thyroid papillary carcinoma [Tiroid papiller karsinomlarinda kronik lenfositik tiroidit ve tümörü infiltre eden lenfosit birlikteligi]

Onak Kandemir N. | Barut F. | Keser S. | Karadayi N. | Bektaş S. | Dogan Gün B. | Bahadir B.

Article | 2009 | Turk Onkoloji Dergisi24 ( 4 ) , pp.172 - 176

OBJECTIVES This study examined the frequency of chronic lymphocytic thyroiditis (CLT) in thyroid papillary carcinomas (TPC) and the relationship between the presence of tumor-infiltrating lymphocytes (TIL) and CLT. METHODS The study included 61 TPC cases. In each case, the presence of the lymphocyte infiltration in the tumor tissue and non-neoplastic parenchyma was graded semi-quantitatively using a scale of 0 to 3. The cases were classified in two groups, TPC including CLT (Group I) and TPC not including CLT (Group II). RESULTS CLT was detected in 26.3% (Group I) of the TPCs and TIL was observed in 77% of the Group I cases; no lymp . . .hoid infiltration compatible with TIL was detected in Group II. A significant difference was observed in the TIL density between Groups I and II. CONCLUSION CLT is a frequent finding in TPC, and the presence of TIL is related to CLT. © 2009 Association of Oncology Daha fazlası Daha az

Doppler evaluation of pediatric goiter: Effect of mandatory iodination

Özer T. | Demirel F. | Mahmutyazicioglu K. | Gürel A. | Özdemir H. | Savranlar A. | Demircan N.

Article | 2005 | Journal of Clinical Ultrasound33 ( 7 ) , pp.339 - 344

Purpose. The aim of this study was to evaluate the hemodynamic status of the thyroid in children with goiter after the use of iodinated dietary salt for 3 years in a region of endemic iodine deficiency. Methods. Sixty-six children between 7 and 12 years of age were included in the study. Three groups were constituted according to sonographically measured thyroid volume and urinary iodine excretion levels. Group 1 included 11 children with thyroid volumes greater than the 97th percentile according to age and sex criteria suggested by the World Health Organization International Council for Control of Iodine Deficiency Disorders and ur . . .inary iodine level lower than 100 µg/l. Group 2 included 30 children with thyroid volumes greater than the 97th percentile and urinary iodine level equal to or higher than 100 µg/l. The control group included 25 children who had normal thyroid volume and urinary iodine level. All children were examined by thyroid duplex sonography. Peak systolic velocity (PSV) and resistance index (RI) were measured in the inferior thyroid artery bilaterally. Results. PSV in group 1 was significantly higher than in group 2 and in the control group (P < 0.05 and P < 0.01, respectively). There was no significant difference between the PSV of group 2 and the control group. The RI in groups 1 and 2 was significantly lower than in the control group (P < 0.01 and P < 0.01, respectively). There was no significant difference between the RIs of group 1 and group 2. Conclusions. These findings suggest an effect of iodination on thyroid hemodynamics before the size of the hyperplastic thyroid returned to normal, in keeping with normalization of the urinary iodine level. © 2005 Wiley Periodicals, Inc Daha fazlası Daha az

Doppler Evaluation of the Thyroid in Pediatric Goiter

Mahmutyazicioglu K. | Turgut M.

Article | 2004 | Journal of Clinical Ultrasound32 ( 1 ) , pp.24 - 28

Purpose. The aim of this study was to identify any changes in Doppler parameters in the thyroid arteries of pediatric patients with a clinical diagnosis of goiter living in an area where goiter is endemic. Patients and Methods. In this prospective study, 20 pediatric patients with simple endemic goiter and 20 age-matched healthy subjects underwent sonographic examination. The resistance index (RI) and peak systolic velocity (PSV) on duplex sonography were measured from the inferior thyroid arteries, and the thyroid gland volume was recorded. Serum thyrotropin, free T3 hormone, and free T4 hormone levels were measured in both groups. . . . Results. The mean thyroid volume (± standard deviation) was significantly higher in the patients than in the healthy subjects (7.2 ± 1.4 ml versus 3.2 ± 1.1 ml; p < 0.01). The mean RI values for the thyroid arteries were significantly lower in the patient than in the control group (0.58 versus 0.70, respectively; p < 0.05). The mean PSV of the thyroid arteries was significantly higher for the patients than for the healthy subjects (mean, 36.7 cm/second versus 18.3 cm/second, respectively; p < 0.05). There was no correlation between the Doppler parameters and any of the hormone levels evaluated. Conclusions. In the arteries supplying the thyroid gland in a pediatric population, Rls were lower and PSVs higher in the patients with diffuse goiter than in the healthy control group. We discuss iodine deficiency as a possible mechanism for these changes. © 2003 Wiley Periodicals, Inc Daha fazlası Daha az

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