Bulunan: 8 Adet 0.002 sn
Koleksiyon [3]
Tam Metin [1]
Yayın Türü [3]
Yazar [20]
Yayın Yılı [7]
Konu Başlıkları [20]
Yayıncı [5]
Yayın Dili [2]
Dergi Adı [8]
Natural anticoagulant protein levels in Turkish patients with inflammatory bowel disease

Cakal B. | Gokmen A. | Yalinkilic M. | Cakal E. | Ayaz S. | Nadir I. | Ozin Y.

Article | 2010 | Blood Coagulation and Fibrinolysis21 ( 2 ) , pp.118 - 121

Thromboembolism is an important cause of morbidity and mortality in patients with inflammatory bowel disease (IBD). The aim of this study was to investigate common thrombophilic markers in patients with IBD and to search for a relation between these predisposing factors and activity of disease. Seventy-four patients with ulcerative colitis, 22 patients with Crohn's disease and 20 healthy volunteers were enrolled into the study. Plasma levels of protein C, protein S, antithrombin III and activated protein C resistance were determined in patients with IBD and healthy controls. Mean values of protein C, protein S and antithrombin III w . . .ere significantly lower in patients with ulcerative colitis and Crohn's disease compared with the healthy control group. Patients with active ulcerative colitis had lower protein C, protein S and antithrombin III level than patients in remisssion (P < 0.001, P < 0.001, P < 0.001). Levels of protein C, S and antithrombin III were also decreased in patients with active Crohn's disease compared with those in remission (P < 0.05, P < 0.001, P < 0.05). Differences in all natural anticoagulant levels between patients in remission and healthy individuals in both ulcerative colitis and Crohn's disease groups were not statistically significant (P > 0.05). No significant difference was observed in activated protein C resistance (APCR) between patients with active disease, those in remission and the control group (P > 0.05). Abnormalities in natural anticoagulants are common in patients with IBD during active disease. © 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins Daha fazlası Daha az

Ulcerative colitis and thrombosis [Ülseratif kolit ve tromboz]

Şahan C. | Öztürk M.

Article | 2002 | Ondokuz Mayis Universitesi Tip Dergisi19 ( 4 ) , pp.287 - 290

Inflammatory bowel disease (IDB) is systemic disorder. An increased risk of arterial and venous thrombosis was originally reported by Borgen and Barker in 1936. Clinically, it is seen only 1-3% of patients admitted to the hospital for IBD. Ulcerative colitis may be complicated by macrovascular thrombosis. The most common manifestations are deep vein thrombosis of the leg and pulmonary emboli. Several mechanisms have been described which might explain an increased tendency for thromboembolic events in patients with IBD. Genetic risk factors for venous thrombosis are classified as deficiencies of protein C, protein S, antitrombin III, . . . factor V leiden and protrombin 20210, hyperhomocysteinemia Daha fazlası Daha az

Mondor disease of penis; a rare entity mimicking peyronie's disease [Penisin Peyronie Hastalığını Taklit Eden Nadir Bir Antite; Mondor Hastalığı]

Acar T. | Efe D. | Buldu İ. | Acar S. | Yıldız M. | Güneyli S.

Article | 2015 | Duzce Medical Journal17 ( 2 ) , pp.79 - 81

Mondor’s disease of the penis is a rare entity characterized by thrombosis in the dorsal penile vein. Unlike anxiety resulting from this condition which is conservatively treated, recognizing this disease is quite easy with Doppler ultrasonography. Peyronie’s disease and sclerosing lymphangitis are considered in the differential diagnosis of Mondor’s disease. In this present case report we aimed to present ultrasonography findings and briefly review the literature in a male patient diagnosed with Mondor’s disease who admitted with rope like stiffness on the dorsal side of penis mimicking Peyronie's disease. © 2012 Düzce Medical Jour . . .nal Daha fazlası Daha az

No suspicion, no disease! renal infarction: Case series

Karacabey S. | Hocagil . | Sanri E. | Hocagil A.C. | Ardic S. | Suman E.

Note | 2014 | Urology Journal11 ( 6 ) , pp.1984 - 1986

[No abstract available]

Our open heart surgery experience in factor XII deficiency: A case report [Faktör XII eksikliginde açik kalp cerrahisi deneyimimiz: Olgu sunumu]

Coşkun E. | Büyükateş M.

Article | 2016 | Turkish Journal of Thoracic and Cardiovascular Surgery24 ( 3 ) , pp.561 - 564

Factor XII deficiency is an important hematological problem which is characterized by isolated prolongation of the activated partial thromboplastin time and presents with thrombosis and thromboembolism tendency rather than expected bleeding diathesis in clinical practice. A 55-year-old male patient who was scheduled for aortic coronary bypass graft surgery had elevated activated partial thromboplastin time (109.4 sec) as a laboratory finding. The patient was diagnosed with factor XII deficiency and operated in our clinic. No thromboembolic event was seen during follow-up. The patient was discharged in the seventh postoperative day u . . .neventfully. Herein, we highlight the importance of this disease due to its rare occurrence and present our treatment strategy applied Daha fazlası Daha az

Experience with the Edwards MIRA mechanical bileaflet valve: In the aortic and mitral positions

Kale A. | Yildiz U. | Can B. | Kandemir O. | Tokmakoglu H. | Tezcaner T. | Zorlutuna, Yaman

Article | 2006 | Texas Heart Institute Journal33 ( 3 ) , pp.328 - 332

The Edwards MIRA bileaflet mechanical prosthesis, a heart valve not yet available in the United States, is designed with a unique hinge mechanism, curved leaflets, and thin titanium housing. We performed this study to investigate its clinical performance and postoperative hemodynamic results. We implanted 58 Edwards MIRA prostheses in 51 patients in the aortic (n=18), mitral (n=26), and aortic and mitral (n=7) positions. Patients' ages ranged from 25 to 84 years (mean age, 53.7 ± 13.6). Operative mortality was 2% (n=1), and late mortality was 4% (n=2). Thromboembolic events were observed in 2 patients (valve thrombosis in 1 and a ce . . .rebrovascular event in 1). There were no complications related to anticoagulation. No signs of valvular dysfunction or paravalvular leakage were observed. Peak transvalvular gradients of the aortic prostheses ranged from 24.25 ± 5.32 mmHg for the 21-mm valve to 11 ± 1.41 mmHg for the 25-mm valve. The effective orifice area ranged from 1.99 ± 0.12 cm2 for the 21-mm valve to 2.44 ± 0.17 cm2 for the 25-mm valve. The mean transvalvular gradients of the mitral prostheses ranged from 5.85 ± 2.91 mmHg for the 27-mm valve to 4.5 ± 0 mmHg for the 31-mm valve. The effective orifice area ranged from 2.31 ± 0.03 cm2 for the 27-mm valve to 2.64 ± 0.05 cm2 for the 33-mm valve. These preliminary data suggest good hemodynamic function and a low rate of valve-related complications in the use of the Edwards MIRA mechanical prosthesis. © 2006 by the Texas Heart® Institute Daha fazlası Daha az

Right ventricular thrombus formation and pulmonary embolism as a complication of behçet disease: Case report

Yavuz N. | Karabad T. | Çabuk M. | Sayin M.R. | Aktop Z. | Gursoy Y.C.

Article | 2015 | Turkiye Klinikleri Cardiovascular Sciences27 ( 1 ) , pp.32 - 35

Behçet disease is a chronic, inflammatory, multisystemic vasculitis mainly characterized by orogenital ulcers. It is mainly observed in Turkey, other Mediterranean areas, and Japan. Viral, bacterial, genetic, immunologic, and environmental factors have been implicated in the pathogenesis of the disease. Although disease is multisystemic, cardiac involvement is rare and often associated with poor prognosis. Hypercoagulopathy is one of the important manifestation of the Behçet disease. Thromboembolic events such as myocardial infarction, stroke and pulmonary embolism risk is higher in patients with Behçet compared to normal population . . .. Right ventricular thrombus is a quite rare. In this paper we present a 26-year-old male patient who presented with pulmonary embolism and was subsequently diagnosed with a right ventricular thrombus and completely recovered after treatment. We also discussed diagnostic and therapeutic options. © 2015 by Turkiye Klinikleri Daha fazlası Daha az

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