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İptal
Bulunan: 88 Adet 0.002 sn
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Filtreler
Filtreler
Bulunan: 88 Adet 0.002 sn
Koleksiyon : Makale Koleksiyonu ( ... ✕
Koleksiyon [19]
İlgili Araştırmacılar [26]
Ambargo Durumu [1]
Tam Metin [2]
Yazar [90]
Yayın Türü [5]
Yayın Yılı [14]
Yayın Dili [2]
Dergi Adı [56]
Yayıncı [16]
Konu Başlıkları [90]

Effects of Impaired Fasting Glucose on Aortic Elasticity

Dogan, S. M. | Aktop, Z. | Aydin, M. | Karabag, T. | Sayin, M. R. | Bilici, H. M. | Atmaca, H.

Background: The pathophysiology of atherosclerosis development in patients with diabetes mellitus (DM) is similar to that in nondiabetics. However, atherosclerosis develops earlier and runs a rapid course in patients with diabetes. Aortic stiffness, strain and distensibility are the parameters used to assess an increase in arterial stiffness and can be measured by invasive and non-invasive methods. Method: Aortic elastic properties were compared among patients with normal oral glucose tolerance test but impaired fasting glucose and healthy individuals. The study group consisted of 50 subjects ...Daha fazlası

Makale 2012 EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES120 ( 7 ) , pp. 4 - 427 815 Görüntülenme

Prevalence of asthmatic smokers: Turkish experience (PASTE Study)

Yıldız, Fusun | Dursun, Adile Berna | Dişçi, Rian | Abadoğlu, Öznur | Atalay, Figen | Ateş, Güngör | Büyükoğlan, Hakan

Background: Although both asthma and smoking are major health problems worldwide, smokers are often excluded from asthma studies. Objectives: It was aimed to verify the prevalence of asthmatic smokers in Turkey and assess the effects of smoking based on clinical parameters, exacerbations and hospitalizations because of lack of national data about the prevalence of smoking among asthmatics. Methods: The study protocol was comprised of a retrospective questionnaire. The asthmatic patients were followed in the outpatient clinics of 18 tertiary hospitals selected from seven different geographical ...Daha fazlası

Makale 2014 Clinical Respiratory Journal8 ( 3 ) , pp. 3 - 356 1093 Görüntülenme
Erişime Açık

The effect of radiotherapy on cardiac function

Dogan S.M. | Bilici H.M. | Bakkal, Bekir Hakan | Aydin M. | Karabag T. | Sayin M.R. | Aktop Z.

BACKGROUND: Radiation-induced heart disease is a complication that may be encountered after radiotherapy (RT) of tumors in the vicinity of the heart. In this study, we aimed to evaluate the effect of RT on the heart, by comparing conventional and tissue Doppler echocardiography parameters obtained before and after RT. METHODS: Forty patients who had undergone RT for either lung or left breast cancer were included in the study. ECG, conventional, and tissue Doppler echocardiography were performed before and 4-6 weeks after RT. RESULTS: The mean value of the radiation dose applied to all regions ...Daha fazlası

Makale 2012 Coronary Artery Disease23 ( 3 ) , pp. 1 - 154 1313 Görüntülenme
Erişime Açık

Celiac disease in patients having recurrent aphthous stomatitis

Aydemir, Selim | Tekin, Solak Nilgün | Aktunç, Erol | Numanoğlu, Gamze | Üstündağ, Yücel

Amaç: Celiac hastalığı ince barsakların glutene intoleransı sonucu oluşan bir hastalıktır. Epidemiolojik çalışmalarda prevalansı hakkında çok farklı veriler vardı. Hastalarda genellikle çok geniş spektrumda semptom ve bulgulara neden olabildiğinden celiac hastalığı tanısının konulması zor olabilmektedir. Hastalığın erken evrede yakalanması önemlidir. Çünkü bu hastalarda barsak lenfoması gelişme riski artmıştır. Celiac hastalığı olan hastalarda rekürren aftoz stomatit prevalansındaki yükseklik nedeniyle rekürren aftoz stomatitli hastaların celiac hastalığı yönünden araştırılması asemptomatik ce ...Daha fazlası

Makale 2004 Turkish Journal of Gastroenterology15 ( 3 ) , pp. 1 - 195 1033 Görüntülenme
Erişime Açık

Treatment of severe amitriptyline intoxication with plasmapheresis

Kolsal, Ebru | Tekin, İshak Özel | Pişkin, Etem | Aydemir, Cumhur | Akyüz, Mehmet | Çabuk, Hasan | Eldes, Nilüfer | Numanoğlu, Kemal Varın

Tricyclic antidepressant poisoning is one of the most common causes of serious intoxication. Here, we report a 2-year-old girl with severe amitriptyline (70 mg/kg) intoxication. She was in comatose, had generalized tonic clonic seizure, ventricular tachycardia, and wide QRS complexes. Although she did not respond to classical therapies, very good clinical response to plasmapheresis was obtained and she developed no complications. Thus, plasmapheresis may be an effective treatment modality in poisoning with drugs, which bind to plasma proteins with high affinity. © 2009 Wiley-Liss, Inc.

Makale 2009 Journal of Clinical Apheresis24 ( 1 ) , pp. 2 - 24 1375 Görüntülenme
Erişime Açık

Vitamin E protects against acetone-induced oxidative stress in rat red blood cells

Armutçu, Feraf | Coşkun, Ömer Faruk | Gürel, Aykut | Şahin, S. | Kanter, Marek | Cihan, Ali | Numanoğlu, Kemal Varın

Acetone may induce oxidative stress leading to disturbance of the biochemical and physiological functions of red blood cells (RBCs) thereby affecting membrane integrity. Vitamin E (vit E) is believed to function as an antioxidant in vivo protecting membranes from lipid peroxidation. The aim of the present study was the evaluation of possible protective effects of vit E treatment against acetone-induced oxidative stress in rat RBCs. Thirty healthy male Wistar albino rats, weighing 200-230 g and averaging 12 weeks old were randomly allotted into one of three experimental groups: Control (A), ace ...Daha fazlası

Makale 2005 Cell Biology and Toxicology21 ( 1 ) , pp. 5 - 60 1208 Görüntülenme

Pharmacological preconditioning with erythropoietin reduces ischemia-reperfusion injury in the small intestine of rats

Sayan, Hale | Özaçmak, Veysel Haktan | Şen, Feyza | Çabuk, Mehmet | Atik-Yörük, Duygu | Akyıldız-İğdem, Ayşenur | Özaçmak, I. Diler

Aims: Considering the implications that arose from several recent experimental studies using recombinant human erythropoietin in rodents, erythropoietin has been regarded as a pharmacological preconditioning agent. The purpose of the present study was to evaluate whether erythropoietin has a preconditioning effect against ischemia and reperfusion injury in the small intestine of the rat. Main methods: Intestinal ischemia was induced in male Wistar rats by clamping the superior mesenteric artery for 30 min, followed by reperfusion for 180 min. Recombinant human erythropoietin (1000 or 3000 U/kg ...Daha fazlası

Makale 2009 Life Sciences84 ( 11.Dec ) , pp. 3 - 371 1072 Görüntülenme
Erişime Açık

Guttate psoriasis-like lesions following BCG vaccination

Koca, Rafet | Altinyazar, H. Cevet | Numanoğlu, Gamze | Ünalacak, Murat

A 7-year-old boy presented to our clinic with a 1-week history of guttate psoriasis-like lesions after BCG vaccination. Although the patient did not have any history of psoriasis, his father and uncle had a history of psoriasis vulgaris. He was treated successfully with topical corticosteroid. Complete healing was seen after 3 weeks and the patient was still in remission 4 months after the cessation of the therapy. We proposed that patients who have psoriasis or predisposition to psoriasis must be carefully followed after BCG vaccination. © Oxford University Press 2004; all rights reserved.

Makale 2004 Journal of Tropical Pediatrics50 ( 3 ) , pp. 1 - 179 505 Görüntülenme
Erişime Açık

Protective effects of L-arginine on rat terminal ileum subjected to ischemia/reperfusion

Sayan, Hale | Özaçmak, Veysel Haktan | Altaner, Şemsi | Aktaş, R. Gülhan | Arslan, S. Oktay

OBJECTIVES: Studies have shown that nitric oxide (NO) may play a major role in sustaining mucosal integrity; however, NO has been also implicated in the pathogenesis of ischemia/reperfusion (I/R)-related tissue injury. We investigated the effects of L-arginine and N-nitro L-arginine methyl ester (L-NAME) on the acetylcholine-induced contractile response of ileum and the levels of malondialdehyde (MDA) and reduced glutathione (GSH). Histopathological changes were also evaluated in ileal preparations. MATERIALS AND METHODS: Male Wistar Albino rats were subjected to mesenteric ischemia (30 min) f ...Daha fazlası

Makale 2008 Journal of Pediatric Gastroenterology and Nutrition46 ( 1 ) , pp. 2 - 35 318 Görüntülenme
Erişime Açık

Erdosteine improves oxidative damage in a rat model of renal ischemia-reperfusion injury

Gürel, Ahmet | Armutcu, Ferah | Cihan, Alper | Numanoğlu, Kemal Varın | Unalacak, Murat

The aim of the present study was to determine the effects of erdosteine, a new antioxidant and anti-inflammatory agent, on lipid peroxidation, neutrophil infiltration, and antioxidant enzyme activities in a rat model of renal ischemia-reperfusion (I/R) injury. Twenty-eight rats were divided into three groups: sham operation, I/R, and I/R plus erdosteine groups. After the experimental procedure, rats were sacrificed and kidneys were removed and prepared for malondialdehyde (MDA) levels, myeloperoxidase (MPO), xanthine oxidase (XO), catalase (CAT) and superoxide dismutase (SOD) activities. MDA l ...Daha fazlası

Makale 2004 European Surgical Research36 ( 4 ) , pp. 2 - 209 1208 Görüntülenme
Erişime Açık

Angiolupoid type cutaneous sarcoidosis on the auricle: A case report [Kulak kepçesinde anjiyolupoid tip kutanöz sarkoidoz olgusu]

Koca, Rafet | Çınar, Saniye | Numanoğlu, Gamze | Altınyazar, H. Cedet | Solak-Tekin, Nilgün | Muhtar, Şennur

Sarcoidosis is a multisystem disorder of unknown etiology, which is histopathologically characterized by noncaseating granulomas. Cutaneous sarcoidosis localizing on the auricle may be observed in various clinical types. Angiolupoid sarcoidosis is a rare form of cutaneous sarcoidosis. We describe a 26-year-old white man with angiolupoid cutaneous sarcoidosis localized on the auricle without systemic involvement. Copyright © 2006 by Türkiye Klinikleri.

Makale 2006 Turkiye Klinikleri Journal of Medical Sciences26 ( 4 ) , pp. 4 - 456 1056 Görüntülenme
Erişime Açık

Morphine modulates inducible nitric oxide synthase expression and reduces pulmonary oedema induced by α-naphthylthiourea

Cömert, Mustafa | Sipahi, Emine Yılmaz | Üstün, Hüseyin | Işıkdemir, Fulden | Numanoğlu, Gamze | Barut, Figen | Altunkaya, Hanife | Özer, Yetkin | Ayoğlu, Ferruh Niyazi | Sipahi, Tunç Hakan | Tekin, İshak Özel | Banoğlu, Z. Nur

This study was designed to investigate the possible participation of morphine in pulmonary oedema induced by ?-naphthylthiourea (ANTU), which is a well-known noxious chemical agent in the lung. Injection of ANTU (15 mg/kg i.p.) produced pulmonary oedema as indicated by an increase in lung weight/body weight ratio and pleural effusion reaching a maximum within 4 h in rat. Administration of morphine prior to ANTU significantly inhibited to pulmonary oedema with a dose-dependent manner. The protective effect of morphine is prevented by peripheral opioid receptor antagonist, naloxone methiodide. A ...Daha fazlası

Makale 2005 European Journal of Pharmacology511 ( 02.Mar ) , pp. 1 - 189 1704 Görüntülenme
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