Bulunan: 40 Adet 0.001 sn
Koleksiyon [13]
Tam Metin [2]
Yayın Türü [3]
Yazar [20]
Yayın Yılı [12]
Konu Başlıkları [20]
Yayıncı [1]
Yayın Dili [2]
Dergi Adı [6]
Paracardiac giant cystic desmoid tumour: Case report

Akpinar I. | IşLEYEN A. | Durukan M. | Güray Ü. | Acu R. | TÜFEKçIOgLU O. | GÖLBAşI Z.

Article | 2013 | Turkiye Klinikleri Cardiovascular Sciences25 ( 3 ) , pp.162 - 165

Desmoid tumours, also called aggressive fibromatosis, are an extremely rare type of tumour arising from musculoaponeurotic tissues. Their etiology is still unknown. They are usually benign, but local invasion and relapsing are frequent. Here we report the case of a 45-year-old male patient with widespread invasion of a desmoid tumour involving superior-posterior mediastinum, retroperitoneum and right lumbocostal region. The tumour was inoperable because of important vascular and cardiac invasions. Despite the intra-abdominal location of most desmoid tumours, involvement of the superior mediastinum and their differential diagnosis am . . .ong the retroperitoneal-mediastinal masses should be definitely kept in mind. Transthoracic ecocardiography should be considered as a first method for the assessment of mediastinal invasion. Copyright © 2013 by Türkiye Klinikleri Daha fazlası Daha az

The use of Alloxan and Streptozotocin in Experimental Diabetes Models [Deneysel Diyabet Modellerinde Alloksan ve Streptozotosin Kullanımı]

Kurçer Z. | Karaoglu D.

Review | 2012 | Turkish Journal of Endocrinology and Metabolism16 ( 2 ) , pp.34 - 40

Diabetes is a chronic metabolic disease which leads to several acute and chronic complications, morbidity and mortality, and decreased lifespan and quality of life. Therefore, in research studies that aim to enlighten the pathogenesis of diabetes and investigate possible treatment strategies, experimental animal models of diabetes provide many advantages to the investigator. Models of diabetes obtained by chemical induction, diet, surgical manipulations or combination thereof and also new genetically modified animal models are some of the experimental models. Alloxan and streptozotocin (STZ), which are toxic glucose analogues that p . . .referentially accumulate in pancreatic beta cells, are widely used toxic agents to induce experimental diabetes in animals. This review gives an overview on the use of alloxan and STZ to induce chemical diabetes models with reference to their mechanisms, utilizable doses, advantages and disadvantages in diabetes research Daha fazlası Daha az

Simultaneous occurrence of different follicular neoplasms within the same thyroid gland [Aynı tiroid bezinde farklı foliküler hücre kökenli neoplazilerin birlikteliği]

Polat Ş.B. | Arpacı D. | Yazgan A. | Başer H. | Kılıç M. | Ersoy R. | Çakır B.

Article | 2016 | Turkish Journal of Endocrinology and Metabolism20 ( 2 ) , pp.31 - 35

Purpose: Neoplasms of the thyroid gland are classified according to the cells they originate from and commonly develop from cells of follicular origin. The most common differentiated thyroid cancers (DTC) are papillary and follicular carcinomas. Coexistence of two different histological types of primary follicular thyroid neoplasm is a rare condition. There are previous reports of concomitant medullary and papillary thyroid cancers. However, there is scarce data about the simultaneous occurrence of the two different histological types of primary follicular thyroid tumors and this is the first study on that subject. Material and Meth . . .od: From January 2007 to September 2014, our institutional database was reviewed for patients who underwent thyroid surgery for various indications. Medical records and cytopathology reports of those patients were examined retrospectively. Simultaneous neoplasms of follicular origin were noted. Results: A total of 3.700 patients were operated. Histopathological examination revealed a benign pattern in 2.686 (73%) patients and a malignant pattern in 1.014 (27%) patients. Among the patients with the diagnosis of DTC, only 20 (1.9%) had a concomitant neoplasm within the same thyroid gland. Discussion: Such simultaneous tumors may be a part of a familial tumor syndrome or an unidentified novel gene mutation playing role in the pathogenesis of more than one type of tumor. Based on the current evidence, the synchronous occurrence of those neoplasms in a given patient is likely coincidental in the literature. Further studies on larger patient population with standardized genetic characterization are needed. © 2016, Galenos Yayincilik. All rights reserved Daha fazlası Daha az

Electronic reference use and publication ethics in scientific articles in the area of health sciences [Saglık bilimleri alanındaki bilimsel makalelerde elektronik kaynak kullanımı ve yayın etigi]

Atici E. | Ercan I. | Cangür Ş. | Büyükuysal Ç.

Article | 2013 | Turkiye Klinikleri Journal of Medical Sciences33 ( 2 ) , pp.448 - 454

Turkish version of the parenting stress index short form: A psychometric study

Mert E. | Hallioglu O. | Ankarali Çamdeviren H.

Article | 2008 | Turkiye Klinikleri Journal of Medical Sciences28 ( 3 ) , pp.291 - 296

Objective: The aim of this study was to assess the psychometric details of the Turkish version of the Parenting Stress Index/Short Form (PSI/SF). Material and Methods: PSI/SF was administered to 90 mothers of children with congenital heart disease in the cardiology outpatient clinic. In 51 mothers the scale was re-administered 2 months later. Psychometric testing was carried out by using Cronbach's alpha, item-total correlations, test-retest reliability and validity. The concurrent validity of the instrument was established by correlating test scores with scores from 2 other well-known depression inventories (Beck and Zung Depressio . . .n inventories). Results: Psychometric analysis showed that the Turkish version of the PSI/SF demonstrated satisfactory internal consistency (Cronbach's alpha) for Total Stress Score (0.71) and also for subscales including Parental Distress (0.81), Parent-Child Dysfunctional Interaction (0.76) and Difficult Child (0.78). Test-retest correlations (r= 0.88) indicated good stability over a mean time period of two months. The PSI/SF was in good correlation with Beck Depression (r= 0.77) and Zung Depression (r= 0.69) inventories. Conclusion: PSI/SF is an appropriate tool for measuring parenting stress in Turkish mothers of children with congenital heart disease and has cross-cultural validity Daha fazlası Daha az

Investigation of intrafamilial transmission in Hepatitis B surface Antigen (HBsAg) positive cases in Harran University Hospital [Harran Üniversitesi Araştirma Hastanesinde Hepatit B yüzey Antijeni (HBsAg) pozitif olgularda aile i·çi bulaşin i·ncelenmesi]

Yengil E. | Kurçer M.A. | Sirmatel F.

Article | 2009 | Turkiye Klinikleri Journal of Medical Sciences29 ( 6 ) , pp.1612 - 1617

Objective: Hepatitis B virus (HBV) is a public health problemowing to communicable and widespreant. In addition to It is important issue because of preventable and prevent to people from contaminated persons. Transmission of HBV may be connected to transmission carrecteristics such as horizontal, vertical, sexual and blood, priority. Aim of this study is to determine the possible route of HBV transmission throughout a family setting. Material and Methods: 173 members (29 spouses, 82 offspring, 11 mothers, 11 fathers and 40 siblings) of 40 index cases (HBsAg carriers and chronic active hepatitis cases) attending the Harran University . . . Medical Faculty Hospital between Augst 2006 and March 2007 were screened prospectively for markers of HBV by using an ELISA. The chi-squared and Logistic regression analyses were used for statistical analysis. Results: Index cases was 18.8% of all family members, while HBsAg prevalence is 15.0% among family members except index cases. Among family members, the highest prevalences of antiHBc were in the mothers (54.5%) and sisters (45.5%), brothers (33.3%), sons (32.6%)and wifes (31.3%), the least prevalences of antiHBc were husbands (7.7%), fathers (18.2%), and doughters (22.2%) of all index cases. Transmission of HBV to both the mothers and sisters were positive was high, Transmission of HBV to fathers was low in all families. There was significant difference in cases where only the mother and husbands of index cases for HBV transmission (p= 0.012). In the logistic regression model; living with chronic hepatitis B index case (OR= 1.92; CI= 1.03-3.57), to be illiterate (OR= 6.81 CI= 1.27-22.13), born at home with traditional methods (OR= 3.70; CI= 1.15-11.87) and born at home with the help of midwife (OR= 3.44; CI= 1.47-7.91) were higher risk for hepatitits B transmision. Conclusion: The family members of index cases with inactive HBV carriers, particularly in the case of chronic active hepatitis have a high risk of transmission. Copyright © 2009 by Türkiye Klinikleri Daha fazlası Daha az

Perinatal brachial plexus palsy: Review [Perinatal brakial pleksus palsisi]

Karadavut K.I. | Başaran A.

Review | 2008 | Turkiye Klinikleri Journal of Medical Sciences28 ( 5 ) , pp.697 - 703

Brachial plexus palsy is caused by a birth injury to the brachial plexus, the nerve network that controls movement and sensation of the arm. The main result of this injury is weak or paralyzed muscles in the shoulder, arm, and hand. Fortunately, most infants with this condition make complete spontaneous recovery. Some, however, are left with varying degrees of arm weakness. Among infants who do not recover spontaneously, some will require physical therapy and occupational therapy only, and others will need both therapy and surgery. Children who develop deformities in the shoulder, arm, or hand may need orthopaedic treatment. In all . . .cases, treatment must be started early to ensure the greatest improvement. Brachial plexus palsy is diagnosed in the newborn. Primary physicians need to identify and refer patients to the multidisciplinary brachial plexus team. During the first 2-6 months after birth, the specialists on the team work together to restore normal functioning of the infant's arm. Copyright © 2008 by Türkiye Klinikleri Daha fazlası Daha az

Serum cystatin C levels in gastric cancer patients: Scientific letter

Demirtaş S. | Uzunoglu N. | Can M. | Karaca L.

Article | 2007 | Turkiye Klinikleri Journal of Medical Sciences27 ( 3 ) , pp.442 - 444

Elevated activities of cysteine proteinases in cancers are attributed to impaired regulation by the endogenous cysteine proteinase inhibitors (cystatins). Cystatin C is suggested to be a reliable marker of glomerular filtration rate (GFR). The purpose of this study was to evaluate whether cystatin C concentration was influenced by gastric malignancy, which is a common cancer type and the availability of this parameter safely for screening renal dysfunction in these patients. Since there is inadequate information on the clinical significance of cystatin C expression in human gastric cancers, we studied the differences in levels of se . . .rum cystatin C in this type of cancer and also evaluated them with respect to cancer stages. The levels of cystatin C in patients with gastric adenocancer were similar to those in the control group. Similarly, the values of serum creatinine and GFR in the patients were comparable to those of the controls. Serum creatinine values in controls and in patients did not show a statistically significant difference 0.8 ± 0.16 and 0.9 ± 0.35 respectively (p> 0.05). Serum cystatin C values in controls and patients were 0.74 ± 0.32 and 0.72 ± 0.6 respectively, which was also not different statistically (p> 0.05). When the patients were evaluated with respect to the stages of the cancer, the cystatin C values did not differ significantly. The mean ± SD levels of the patients in low and advanced stages were 0.79 ± 0.51 and 0.69 ± 0.64 respectively (p> 0.05). Our study clearly demonstrates that serum cystatin C has valuable potential for the detection and monitoring of GFR and may be safely used in gastric cancer patients. Copyright © 2007 by Türkiye Klinikleri Daha fazlası Daha az

The effects of preoperative acupuncture needle and capsicum plaster applications of extra 1, pericardium 6 and large intestine 4 points on preoperative anxiety, postoperative nausea-vomiting and analgesic consumption [Ekstra 1, perikardiyum 6, kahn bagirsak 4 noktalarina preoperatif akupunktur i·gnesi ve kapsikum plasteri uygulamalarinin preoperatif anksiyete, postoperatif bulanti-kusma ve analjezik tüketimine etkisi]

Ayoglu H. | Bayar Ü. | Atik L. | Özer Y. | Acar A. | Özkoçak Turan I.

Article | 2009 | Turkiye Klinikleri Journal of Medical Sciences29 ( 5 ) , pp.1063 - 1070

Objective: The acupuncture points pericardium 6 (P 6), extra 1 (E 1), and large intestine 4 (Li 4) are known to reduce postoperative nausea and vomiting, and to provide sedation and analgesia, respectively. We investigated the effects of preoperative application of acupuncture needle or capsicum plaster on these points on pre-operative anxiety, postoperative nausea and vomiting, and analgesic consumption. Material and Methods: Sixty cases undergoing laparoscopic gynecological operations were divided into four groups. The day before the operation, State Trait Anxiety Inventory (STAI) was given to all cases. The participants were divi . . .ded into four groups regarding the preoperative application of the following: dry needle at points P 6, Li 4 and El in group I; capsicum plaster application at the same points in group II; 0.07 mg kg -1 midazolam im and plasebo plaster application at different non acupunctural points (sham) in group III and only placebo plaster usage at sham points in group IV. STAI was repeated immediately before the operation. After standard general anesthesia, tramadol was administered with postoperative patient controlled analgesia method. Postoperative visual pain score (VAS), analgesic consumption, and nausea and vomiting were recorded. Results: The decrease in the preoperative day 1 STAI scores compared to immediate preoperative scores in group I and group II was significantly higher than the decrease in group III (p< 0.05). Nausea and vomiting rates were lower in group I and II (p< 0.05). The postoperative analgesic consumption of group I and group IV were lower than that of group II and group III (p< 0.05). There was no significant difference between the study groups regarding VAS scores. Conclusion: Preoperative acupuncture needle and capsicum plaster application at P 6, E1, and Li 4 points were found to be effective in reducing pre-operative anxiety and postoperative nausea and vomiting, but thought to be non effective on postoperative analgesic consumption. Noninvasive capsicum plasters are concluded to be a good alternative method for needles that may cause side effects. Copyright © 2009 by Türkiye Klinikleri Daha fazlası Daha az

Varicella infection treated with acyclovir in an elderly patient with rheumatoid arthritis: Case report

Özdolap Ş. | Sarikaya S. | Aktunç E. | Koca R. | Çelebi G.

Article | 2006 | Turkiye Klinikleri Journal of Medical Sciences26 ( 6 ) , pp.689 - 692

Varicella is a common and extremely contagious disease in childhood. The course of infection is usually mild to moderate in children but it may cause serious complications especially in immunosupressed adults and children. We presented a case with nosocomial varicella zoster virus infection in the form of chickenpox in a 67-year-old woman with rheumatoid arthritis (RA) for 15 years who was on treatment of methotrexate and prednisolon. The patient was treated with acyclovir and not only varicella infection but also physical findings and symptoms of RA improved. Copyright © 2006 by Türkiye Klinikleri.

A case of Klatskin tumor with high levels of CA 19-9

Koçak E. | Koçak G. | Beşir F.H. | Can M.

Article | 2007 | Turkiye Klinikleri Journal of Medical Sciences27 ( 5 ) , pp.774 - 777

Carbohydrate antigen 19-9 (CA 19-9) is used as a serum tumor marker for adenocarcinoma of the upper gastrointestinal tract, particularly primary adenocarcinoma of the pancreas. In addition, this tumor marker can be highly elevated in benign diseases such as acute pancreatitis, chronic pancreatitis, chronic liver disease and biliary tract disease. A 69 year-old man was hospitalized with jaundice, colacolored urine, right-sided upper abdominal pain, weight loss and pruritus. Laboratory data revealed a high level of serum CA19-9 of more than 100 000 U/mL and a mass in the left lobe of the liver was detected on computed tomography. ERCP . . ., PTCA and CT-guided biopsy yielded the diagnosis of Klatskin tumor. Review of the literature revealed that Klatskin tumor with high levels of CA 19-9 over 100 000 U/mL was not reported. Copyright © 2007 by Türkiye Klinikleri Daha fazlası Daha az

Angiolupoid type cutaneous sarcoidosis on the auricle: A case report [Kulak kepçesinde anjiyolupoid tip kutanöz sarkoidoz olgusu]

Koca, Rafet | Çınar, Saniye | Numanoğlu, Gamze | Altınyazar, H. Cedet | Solak-Tekin, Nilgün | Muhtar, Şennur

Article | 2006 | Turkiye Klinikleri Journal of Medical Sciences26 ( 4 ) , pp.453 - 456

Sarcoidosis is a multisystem disorder of unknown etiology, which is histopathologically characterized by noncaseating granulomas. Cutaneous sarcoidosis localizing on the auricle may be observed in various clinical types. Angiolupoid sarcoidosis is a rare form of cutaneous sarcoidosis. We describe a 26-year-old white man with angiolupoid cutaneous sarcoidosis localized on the auricle without systemic involvement. Copyright © 2006 by Türkiye Klinikleri.

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