Gastroprotective effects of CoQ10 on ethanol-induced acute gastric lesions

Karakaya K. | Barut F. | Hanci V. | Can M. | Comert M. | Ucan H.B. | Cakmak G.K.

Introduction: Alcohol consumption is frequently associated with gastric mucosal lesions. The purpose of this study was to determine the effect of Coenzyme-Q10 (CoQ10) supplementation on the ethanol-induced gastric mucosal damage in a rat model. Material and method: Sixty-four female wistar albino rats were randomly divided into 8 groups (n = 8). Studies were performed in ethanol induced gastric ulcer model in Wistar albino rats. Famotidine at a dose of 5 mg/kg or 20 mg/kg and CoQ10 at a single dose of 10 mg/kg or 20 mg/kg and 30 mg/kg for 7 days were administered as pretreatment. All the rats ...Daha fazlası

Makale 2015 Bratislava Medical Journal116 ( 1 ) , pp. 5 - 56 899 Görüntülenme

Influence of menstrual cycle on P wave dispersion

Karabag T. | Hanci V. | Aydin M. | Dogan S.M. | Turan I.O. | Yildirim N. | Gudul N.E.

Female gender is an independent risk factor for some types of arrhythmias. We sought to determine whether the menstrual cycle affects P wave dispersion, which is a predictor of atrial fibrillation. The study population consisted of 59 women in follicular phase (mean age, 29.3 ± 7.7 years) (group F) and 53 women in luteal phase (mean age, 28.1 ± 6.8 years) (group L). The ECGs of 35 patients (mean age, 26.4 ± 4.5) were obtained in both follicular and luteal phase. Both groups underwent a standard 12-lead surface electrocardiogram recorded at 50 mm/s. Maximal (Pmax) and minimal P wave durations ( ...Daha fazlası

Makale 2011 International Heart Journal52 ( 1 ) , pp. 2 - 26 1065 Görüntülenme

Evaluation of P wave and corrected QT dispersion in subarachnoid haemorrhage

Hanci V. | Gül S. | Dogan S.M. | Turan I.O. | Kalayci M. | Açikgöz B.

The aim of our study was to investigate P wave dispersion (Pwd), QT, corrected QT (QTc), QT dispersion (QTd) and corrected QT dispersion (QTcd) intervals in subarachnoid haemorrhage. Thirty-five subarachnoid haemorrhage patients (Group S) and 35 neurologically normal patients (Group C) were included in this retrospective study. The standard 12 derivations of the electrocardiograms of all patients were analysed and Pwd, QT and QTd intervals were measured. QTc and QTcd intervals were determined with the Bazett formula. There was no significant difference between the study groups according to dem ...Daha fazlası

Makale 2010 Anaesthesia and Intensive Care38 ( 1 ) , pp. 1 - 132 868 Görüntülenme

Comparison of propofol-dexmedetomidine, tiopental-dexmedetomidine and etomidate-dexmedetomidine combinations' effects on the tracheal intubation conditions without using muscle relaxants

Bollucuoglu K. | Hanci V. | Yurtlu S. | Okyay D. | Ayoglu H. | Turan I.O.

Background: In our study, we aimed to compare the endotracheal intubation conditions without muscle relaxants during induction with the combinations of dexmedotimidine-propofol, dexmedotimidine-thiopenthal and dexmedetomidine-etomidate. Method: Seventy-six patients, in ASA risk group I-II, between ages 20-60 years, with Mallampati Class 1 were included in the study. All patients were premedicated with midazolam. The patients were randomly divided into three groups as Group P (n=30, dexmedetomidine-propofol), Group T (n=30, dexmedetomidine-thiopenthal), Group E (n=16, dexmedetomidine-etomidate) ...Daha fazlası

Makale 2013 Bratislava Medical Journal114 ( 9 ) , pp. 5 - 518 489 Görüntülenme

Non-invasive mechanical ventilation with spinal anesthesia for cesarean delivery

Erdogan G. | Okyay D.Z. | Yurtlu S. | Hanci V. | Ayoglu H. | Koksal B. | Turan I.O.

We present the successful use of perioperative non-invasive mechanical ventilation in a morbidly obese pregnant woman with bronchial asthma, severe preeclampsia and pulmonary edema undergoing an emergency cesarean delivery with spinal anesthesia. The combination of non-invasive mechanical ventilation with neuraxial anesthesia may be of value in selected parturients with acute or chronic respiratory insufficiency requiring surgery. © 2010 Elsevier Ltd. All rights reserved.

Makale 2010 International Journal of Obstetric Anesthesia19 ( 4 ) , pp. 4 - 440 563 Görüntülenme

Effects of dexmedetomidine or methylprednisolone on inflammatory responses in spinal cord injury

Can M. | Gul S. | Bektas S. | Hanci V. | Acikgoz S.

Background: The aim of this study was to compare the anti-inflammatory response of methylprednisolone and the ?2-agonist dexmedetomidine in spinal cord injury (SCI). Methods: Twenty-four male adult Wistar albino rats, weight 200-250 g, were included in the study. The rats were divided into four groups as follows: the control group (n: 6) received only laminectomy; the SCI group (n: 6) with trauma alone; the SCI+methylprednisolone group (n: 6) with trauma and 30 mg/kg methylprednisolone, followed by a maintenance dose of 5.4 mg/kg/h; and the SCI+dexmedetomidine group (n: 6) with trauma and 10 µ ...Daha fazlası

Makale 2009 Acta Anaesthesiologica Scandinavica53 ( 8 ) , pp. 1 - 1072 176 Görüntülenme

Effects of fentanyl-lidocaine-propofol and dexmedetomidine-lidocaine- propofol on tracheal intubation without use of muscle relaxants

Hanci V. | Erdogan G. | Okyay R.D. | Yurtlu B.S. | Ayoglu H. | Baydilek Y. | Turan I.O.

The aim of this study was to compare the effects of fentanyl or dexmedetomidine when used in combination with propofol and lidocaine for tracheal intubation without using muscle relaxants. Sixty patients with American Society of Anesthesiologists stage I risk were randomized to receive 1 µg/kg dexmedetomidine (Group D, n = 30) or 2 µg/kg fentanyl (Group F, n = 30), both in combination with 1.5 mg/kg lidocaine and 3 mg/kg propofol. The requirement for intubation was determined based on mask ventilation capability, jaw motility, position of the vocal cords and the patient's response to intubatio ...Daha fazlası

Makale 2010 Kaohsiung Journal of Medical Sciences26 ( 5 ) , pp. 2 - 250 744 Görüntülenme

A comparison of spinal anesthesia with low-dose hyperbaric levobupivacaine and hyperbaric bupivacaine for transurethral surgery: A randomized controlled trial

Erbay R.H. | Ermumcu O. | Hanci V. | Atalay H.

Background. The aim of this study was to compare spinal anesthesia effects of low-dose hyperbaric levobupivacaine and low-dose hyperbaric bupivacaine for transurethral procedures. Methods. In this double-blind, randomized, controlled study, a total of 60 patients who were ASA I-III were randomized into two groups. Group B received 7.5 mg hyperbaric bupivacaine plus 25 µg fentanyl, and Group L received 7.5 mg hyperbaric levobupivacaine plus 25 µg fentanyl intrathecally. The onset time to T10 dermatome, times to maximum sensory and motor block levels, time to two-segment regression of sensory bl ...Daha fazlası

Makale 2010 Minerva Anestesiologica76 ( 12 ) , pp. 9 - 1001 290 Görüntülenme

A subhypnotic dose of ketamine reduces pain associated with injection of propofol and rocuronium

Abduşoglu M.N. | Özkoçak I. | Yurtlu B.S. | Hanci V. | Okyay R.D. | Ayoglu H.

[No abstract available]

Mektup 2011 European Journal of Anaesthesiology28 ( 3 ) , pp. 2 - 230 397 Görüntülenme

Coenzyme Q10 treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injury

Erol B. | Bozlu M. | Hanci V. | Tokgoz H. | Bektas S. | Mungan G.

In this experimental study, we assessed the preventive effects of coenzyme Q10 (CoQ10) in a rat model of ischemia/reperfusion injury. The results of this study show that CoQ10 administration before the reperfusion period of testicular torsion provides a significant decrease in testicular lipid peroxidation products and expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and germ cell-specific apoptosis. © 2010 American Society for Reproductive Medicine.

Makale 2010 Fertility and Sterility93 ( 1 ) , pp. 2 - 282 250 Görüntülenme

Investigation of hepatitis G virus prevalence in hemodialysis patients and blood donors in Denizli, Turkey [Denizli'de hemodiyaliz hastalar?nda ve kan donörlerinde hepatit G virus prevalans?n?n araşt?r?lmas?]

Yilmaz Hanci S. | Cevahir N. | Kaleli I. | Hanci V.

This study focuses on the prevalence of hepatitis G virus (GBV-C/HGV) in hemodialysis patients and blood donors in Denizli (located at Aegean region of Turkey). A total of 100 patients (mean age: 56.8 ± 13.3 years; 46 female) receiving hemodialysis and 100 blood donors (mean age: 31.3 ± 8.1 years; 8 female) were included in the study. The presence of GBV-C/HGV RNA was determined in all patients by reverse transcriptase-PCR and the presence of GBV-C/HGV anti-E2 antibodies was determined by a commercial enzyme immunoassay (Diagnostic Automation, INC®). Viral RNA positivity was determined in 14 ( ...Daha fazlası

Makale 2008 Mikrobiyoloji Bulteni42 ( 4 ) , pp. 6 - 625 307 Görüntülenme

Antioxidant vitamins C, E and coenzyme Q10 vs Dexamethasone: comparisons of their effects in pulmonary contusion model

Gokce M. | Saydam O. | Hanci V. | Can M. | Bahadir B.

Background: The goal of our study is to evaluate the effects of antioxidant vitamins (vitamin C and E), Coenzyme Q10 (CoQ10) and dexamethasone (Dxm) in experimental rat models with pulmonary contusion (PC).Methods: Rats were randomly divided into six groups. Except for the control, all subgroups had a moderate pulmonary contusion. Animals in the group I and group II received intraperitoneal saline, group III received 10mg.kg-1 CoQ10 group IV received 100mg.kg-1 vitamin C, group V received 150mg.kg-1 vitamin E, and group VI received 10mg.kg-1 Dxm. Blood gas analysis, serum nitric oxide (NO) and ...Daha fazlası

Makale 2012 Journal of Cardiothoracic Surgery7 ( 1 ) 394 Görüntülenme

Filtreler

Koleksiyon [9]

İlgili Araştırmacılar [17]

Tam Metin [1]

Yazar [90]

Yayın Türü [3]

Yayın Yılı [9]

Yayın Dili [3]

Dergi Adı [31]

Yayıncı [9]

Konu Başlıkları [90]