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Bulunan: 46 Adet 0.110 sn
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Bilateral synchronous squamous cell tonsil carcinoma treated with chemoradiotherapy

Bakkal, Bekir Hakan | Ugur M.B. | Bahadir B.

The incidence of numerous head and neck tumours is a known issue though bilateral synchronous tonsillar carcinoma reports are so uncommon that only 20 cases were found in a literature review. Most of these patients were treated with bilateral tonsillectomy followed by adjuvant radiotherapy. We report, to our knowledge, the first case of bilateral synchronous tonsillar squamous cell carcinoma treated only with chemoradiotherapy without tonsillectomy.

Traumatic neuromas: A histopathologic and immunohistochemical study [Travmatik nöromalar: Histopatolojik ve i·mmünohistokimyasal bir çalişma]

Özdamar Ş.O. | Dogan Gün B. | Barut F. | Bahadir B.

Objective: Traumatic neuroma is an exuberant, probably non-neoplastic proliferation of a nerve occurring in response to injury or surgery. We studied six cases of traumatic neuroma with light microscopic, histochemical and immunohistochemical methods to assess the cellular compositions of these lesions. Material and Methods: Sections from the formalin-fixed parafin-embedded tissues were stained with hematoxylin-eosin, Gomori's trichrome, Verhoeff elastica-von Gieson, reticuline, and S-100 protein, Epithelial Membrane Antigen, CD34 and CD68. Results: All cases revealed large numbers of small an ...Daha fazlası

Congenital medulloblastoma

Ermis B. | Aydemir C. | Taspinar O. | Cagavi F. | Bahadir B. | Ozdemir H.

[No abstract available]

Elastofibroma: A clinicopathologic and immunohistochemical study of seven cases and literature review

Gun B.D. | Bahadir B. | Behzatoglu K. | Gun M.O. | Ozdamar S.O.

Elastofibroma is a rare fibrous lesion characterized by accumulated abnormal elastic fibers whose etiology remains largely unknown. In this study, we analyzed seven cases of elastofibroma to further explore the characteristics of its cellular composition. Immunohistochemistry was performed for mast cell tryptase, S-100 protein, vimentin, CD34, smooth muscle actin, desmin and collagen type IV. Histochemical staining methods for Gomori's trichrome and Verhoeff elastica-van Gieson were also evaluated. Histopathologically, a haphazard array of collagen, eosinophilic amorphous fibers, and globules ...Daha fazlası

Inverted (hobnail) high-grade prostatic intraepithelial neoplasia and invasive inverted pattern

Öznur M. | Koca S.B. | Yildiz P. | Bahadir B. | Behzatoğlu K.

High-grade prostatic intraepithelial neoplasia (HGPIN) is considered to be an important precursor for prostatic adenocarcinoma. The present study aimed to investigate the histological features of the uncommon inverted (hobnail) pattern of HGPIN in transrectal ultrasonographic (TRUS) prostatic needle biopsies from 13 cases. These 13 diagnosed cases of inverted HGPIN were identified out of a total of 2,034 TRUS biopsies (0.63%), obtained from patients suspected to have prostate cancer. The hobnail pattern is comprised of secretory cell nuclei, which are histologically localized at the luminal su ...Daha fazlası

Noncommunicating thoracolumbar intradural extramedullary arachnoid cyst in an 8-year-old boy: Intact removal by spontaneous delivery

Gul S. | Bahadir B. | Kalayci M. | Acikgoz B.

Noncommunicating spinal intradural extramedullary arachnoid cysts are an extremely rare cause of spinal cord compression. An 8-year-old boy presented with progressive paraparesis. Magnetic resonance imaging revealed a posterior intradural extramedullary arachnoid cyst extending from T11 to L 3 vertebral bodies. The multilevel noncommunicating cyst was totally removed by simple delivery without rupture through a single-level laminoplasty. To our knowledge, no such case has been reported in the literature. Copyright © 2009 S. Karger AG, Basel.

Neuroprotective Effects of Hesperidin on Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage in Rats: Biochemical, Pathologic, and Histomorphometric Analysis

Aydogmus E. | Gul S. | Bahadir B.

Objective: We examined the protective effects of hesperidin on cerebral vasospasm by establishing an experimental rat model of subarachnoid hemorrhage and performing biochemical, pathologic, and histomorphometric analysis on these data. Methods: Forty albino Wistar rats were randomly divided into 5 groups of n = 8 in each: group (G)1, no experimental interventions; G2, subjected to subarachnoid hemorrhage; G3, subjected to subarachnoid hemorrhage and administered saline (100 mg/kg); G4, subjected to subarachnoid hemorrhage and treated with low-dose hesperidin (50 mg/kg); and G5, subjected to s ...Daha fazlası

Choroid plexus carcinoma: Differential diagnosis in papillary tumors of central nervous system [Koroid pleksus karsinomu: Santral sinir sistemi papiller tümörlerinde ayirici tani]

Yurdakan G.N. | Gün B.D. | Bahadir B. | Sönmez A. | Açikgöz B. | Kalayci M. | Özdamar Ş.O.

Choroid plexus carcinoma which is a rare malign tumor of central nervous system. These tumors constitue 20-30% of the primary choroid plexus tumors and are more frequently situate in the lateral ventricle. Choroid plexus carcinoma is invasive and involves areas of necrosis and hemorrhage. Our case is a 4 year old girl who was admitted to university hospital presented with headache, stupor and lethargy. In cranial computerized tomography, a tumor was detected in right temporoparietal lob. Histopathologically the tumor cells were composed of branching papillary structures surrounding a fibrovasc ...Daha fazlası

Colorectal carcinomas: Clinicopathologic investigation, correlation with expression of estrogen and progesterone receptors

Ekem T.E. | Bahadir B. | Gün B.D. | Bektaş S. | Kertj¸ G. | Yurdakan G. | Özdamar Ş.O.

Correlation in mortality data between breast cancer and colonic cancer, and increased incidence of colonic cancer in women with breast cancer suggest common factors in their etiology. Similarly protective effect of increasing parity from colonic cancer, and relatively better prognosis in women may imply a common role for sex steroid hormones. In this study clinicopathologic parameters as well as estrogen and progesterone receptor expressions of 60 cases of colorec-tal adenocarcinoma were investigated. Most carcinomas were moderately differentiated; stage B2 tumors were predominately located in ...Daha fazlası

Cytological features of pure micropapillary carcinoma of various organs: A report of eight cases

Huq G.E. | Canberk Ş. | Öznur M. | Yildiz P. | Bahadir B. | Behzatoglu K.

Micropapillary carcinoma (MPC) is a rare aggressive tumor, which generally accompanies the primary carcinoma of the organ of its origin, while the pure form is extremely uncommon. Angiolymphatic involvement is widespread and a considerable proportion of the cases present with metastases. The current study presents eight pure MPC cases arising from the breast (n=3), urinary bladder (n=3), parotid gland (n=1) and lung (n=1, presenting with pericardial effusion), with the cytological findings. The eight patients included three female and five male cases aged between 48 and 74 years. The most comm ...Daha fazlası

Expression of adhesion molecules in first trimester spontaneous abortions and their role in abortion pathogenesis

Yurdakan G. | Ekem T.E. | Bahadir B. | Gun B.D. | Kuzey G.M. | Ozdamar S.O.

Background. Early placental development is associated with complex regulatory mechanisms, and molecular communication problems that arise during the developmental process are dangerous for continuation of the pregnancy. As studies on the process of invasion and migration of trophoblast cells have shown the importance of cell-cell and cell-matrix interactions, we examined the effects of adhesion molecules on the mechanism(s) of spontaneous abortions and compared them to elective abortion materials using histopathological and immunohistochemical methods. To the best of our knowledge, this is the ...Daha fazlası

Glioblastoma with primitive neuroectodermal tumor-like features: Case Report [Pirimitif nöroektodermal tümör benzeri özellikler gösteren glioblastom: Olgu sunumu]

Onak Kandemir N. | Bahadir B. | Gül Ş. | Karadayi N. | Özdamar S.O.

Glioblastoma multiforme (GB) is the most aggressive, and the most frequent primary tumor of the brain in adults. Presence of less-differentiated areas which exhibit a small cell morphology and neural immunophenotype is quite uncommon in GBs. Tumor tissue which had been determined in the frontotemporal region of a 61-year-old female patient and evaluated to be consistent with GB radiologically was subjected to total excision. Histopathological examination revealed two different components making up the tumor tissue. Using a morphological and immunophenotypic approach, the predominant component ...Daha fazlası

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