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Türkiye’de uluslararası öğrenciler

Özer, Mahmut

Article | 2012 | Yükseköğretim ve Bilim Dergisi2 ( 1 ) , pp.10 - 13

Son yıllarda dünya genelinde sayıları üç milyonun üzerinde olan uluslararası öğrencileri kendi ülkelerinin yükseköğretim kurumlarına alabilmek için ülkeler kıyasıya rekabet etmektedirler. Uluslararası öğrenciler, artık yükseköğretim sistemleri ve kurumlarının uluslararasılaşma boyutlarının en önemli göstergelerinden birisini oluşturmaktadır. Bu bağlamda, yükseköğretim sistemimiz ve kurumlarımızın bu göstergesinin ne durumda olduğunun tespiti, oldukça büyük bir genişleme yaşayan yükseköğretim sistemimiz açısından büyük önem arz etmektedir. Bu çalışmada, ülkemizdeki uluslararası öğrencilerin durumu ele alınmaktadır There are over thre . . .e million international students worldwide, and in recent years higher education institutions compete with each other in order to receive these students to their institutions. International students are now one of the most important indicator of the internationalization of the higher education systems and institutions. In this context, the detection of the status of this indicator in our higher education system and institutions is of great importance as our higher education system shows a large expansion. This study, discusses the status of international students in our countr Daha fazlası Daha az

Change in response time of neuronal populations with noise, synaptical interactions and stimulus frequency

Özsoy, Muhammet Ali | Uzuntarla, Muhammet | Özer, Mahmut


Neurons which are the fundamental elements of the nervous system, encode the information about stimulus they received from the external world by sensory system into action potential (spike) sequences before transmitting to the brain. In this study, a neuron population is modeled in mathematical manner and then first spike appearance time in a spike train is examined against changes in the characteristics of the periodic forcing. We also examine the effect of noise which stems from the biophysical structure of neurons and the effect of synaptic coupling which is the consequence of synaptic interaction of neurons with each other in th . . .e population to the appearance time of first spikes. The obtained results show that the mean response time of the population decreases with the increasing frequency. When the intensity of inherent noise in the neuronal environment increased, it shows a decreasing effect on the mean response only for low frequency range of the stimulus. Although the synaptic interaction coefficient does not affect substantially the mean response time of the population, it was shown that it is the fundamental parameter controlling the standard deviation of the response time Daha fazlası Daha az

A computer software for simulating single-compartmental model of neurons

Özer, Mahmut | İşler, Yalçın | Özer, Halil

Article | 2004 | Computer Methods and Programs in Biomedicine75 ( 1 ) , pp.51 - 57

In this paper, a new computer software package, Yalzer, is introduced for simulating single-compartmental model of neurons. Passive or excitable membranes with voltage-gated ion channels can be modeled, and current clamp and voltage clamp experiments can be simulated. In the Yalzer, first-order differential equations used to define the dynamics of the gate variables and the membrane potential are solved by two separate integration methods with variable time steps: forward Euler and exponential Euler methods. Outputs of the simulation are shown on a spreadsheet template for allowing flexible data manipulation and can be graphically d . . .isplayed. The user can define the model in detail, and examine the excitability of the model and the dynamics of voltage-gated ion channels. The software package addresses to ones who want to run simple simulations of neurons without need to any programming language skills or expensive software. It can also be used for educational purposes. © 2003 Elsevier Ireland Ltd. All rights reserved Daha fazlası Daha az

Activation kinetics of T-type calcium channel by a path probability approximation

Özer, Mahmut

Article | 2004 | NeuroReport15 ( 9 ) , pp.1451 - 1455

We previously formulated dynamics of ion channel gates by the path probability method. In this study, we apply that theoretical approach to derive the activation rate kinetics of T-type calcium channel in thalamic relay neurons. We derive explicit expressions of the forward and backward rate constants and show that the proposed rate constants accurately capture form of the empirical time constant, and that they also provide its saturation to a constant value at depolarized membrane potentials. We also compare our derivations with linear and nonlinear thermodynamic models of rate kinetics obtained from the same calcium channel, and s . . .how that it is possible to capture saturation of the time constant for the depolarized membrane potentials by the only proposed rate constants. © 2004 Lippincott Williams & Wilkins Daha fazlası Daha az

Comparision of classifier performances in diagnosing congestive heart failure using heart rate variability

Narin, Ali | Özer, Mahmut | İşler, Yalçın


In this study, the performance of different discrimination algorithms in the analysis of heart rate variability that are used in discriminating the patients with congestive heart failure from normal subjects were investigated. Classifier algorithms of linear discriminant analysis, k-nearest neighbors, multilayer perceptron, radial basis functions and support vector machines were examined with different parameter values. As a result, the maximum classification accuracy of 91.56% was achieved by using multilayer perceptron with 11 neurons in hidden layer.

Real time detection of alternator failures using intelligent control systems

Uçar, Murat | Bayır, Raif | Özer, Mahmut

Proceedings | 2009 | ELECO 2009 - 6th International Conference on Electrical and Electronics Engineering , pp.1451 - 1455

On todays vehicles, dynamos are being left gradually and alternators take the turn instead for charging systems. Alternator is an electromechanical device which converts mechanical energy into electrical energy. Superior feature of alternators is that they can be charged on idling epoch and they have more output current. On the other hand by using diodes alternative current can be converted into direct current. Alternators are the main component of the charging system on modern vehicles. In this study, alternator failures are detected using fuzzy logic and artificial neural network. These are double diode failure, excessive current, . . . excessive stretch belt, loose belt, loose brush, regulator failure, short circuits on coils, one broken connection on rotor coil, two broken connection on rotor coil, broken connection on tridiode and tridiode short circuit. For detecting the failures, current, accumulator voltage, alternator voltage and the epoch number of the alternator is measured and alternator failure detection classification is implemented by designing an intelligent system inference according to these measured values Daha fazlası Daha az

Controlling the first-spike latency response of a single neuron via unreliable synaptic transmission

Uzuntarla, Muhammet | Özer, Mahmut | Guo D.Q.

Article | 2012 | European Physical Journal B85 ( 8 ) , pp.1451 - 1455

Previous experimental and theoretical studies suggest that first-spike latency is an efficient information carrier and may contain more amounts of neural information than those of other spikes. Therefore, the biophysical mechanisms underlying the first-spike response latency are of considerable interest. Here we present a systematical investigation on the response latency dynamics of a single Hodgkin-Huxley neuron subject to both a suprathreshold periodic forcing and background activity. In contrast to most earlier works, we consider a biophysically realistic noise model which allows us to relate the synaptic background activity to . . .unreliable synapses and latency. Our results show that first-spike latency of a neuron can be regulated via unreliable synapses. An intermediate level of successful synaptic transmission probability significantly increases both the latency and its jitter, indicating that the unreliable synaptic transmission constrains the signal detection ability of neurons. Furthermore, we demonstrate that the destructive influence of synaptic unreliability can be controlled by the input regime and by the excitatory coupling strength. Better tuning of these two factors could help the H-H neuron encode information more accurately in terms of the first-spike latency. © 2012 EDP Sciences, Società Italiana di Fisica, Springer-Verlag Daha fazlası Daha az

Stochastic resonance on Newman-Watts networks of Hodgkin-Huxley neurons with local periodic driving

Özer, Mahmut | Perc, Matjaž | Uzuntarla, Muhammet

Article | 2009 | Physics Letters, Section A: General, Atomic and Solid State Physics373 ( 10 ) , pp.964 - 968

We study the phenomenon of stochastic resonance on Newman-Watts small-world networks consisting of biophysically realistic Hodgkin-Huxley neurons with a tunable intensity of intrinsic noise via voltage-gated ion channels embedded in neuronal membranes. Importantly thereby, the subthreshold periodic driving is introduced to a single neuron of the network, thus acting as a pacemaker trying to impose its rhythm on the whole ensemble. We show that there exists an optimal intensity of intrinsic ion channel noise by which the outreach of the pacemaker extends optimally across the whole network. This stochastic resonance phenomenon can be . . .further amplified via fine-tuning of the small-world network structure, and depends significantly also on the coupling strength among neurons and the driving frequency of the pacemaker. In particular, we demonstrate that the noise-induced transmission of weak localized rhythmic activity peaks when the pacemaker frequency matches the intrinsic frequency of subthreshold oscillations. The implications of our findings for weak signal detection and information propagation across neural networks are discussed. © 2009 Elsevier B.V. All rights reserved Daha fazlası Daha az

Spike latency and jitter of neuronal membrane patches with stochastic Hodgkin-Huxley channels

Özer, Mahmut | Uzuntarla, Muhammet | Perc, Matjaž | Graham, Lyle J.

Article | 2009 | Journal of Theoretical Biology261 ( 1 ) , pp.83 - 92

Double inverse stochastic resonance with dynamic synapses

Uzuntarla, Muhammet | Torres, Joaquin J. | So, Paul | Özer, Mahmut | Barreto, Ernest

Article | 2017 | Physical Review E95 ( 1 ) , pp.83 - 92

We investigate the behavior of a model neuron that receives a biophysically realistic noisy postsynaptic current based on uncorrelated spiking activity from a large number of afferents. We show that, with static synapses, such noise can give rise to inverse stochastic resonance (ISR) as a function of the presynaptic firing rate. We compare this to the case with dynamic synapses that feature short-term synaptic plasticity and show that the interval of presynaptic firing rate over which ISR exists can be extended or diminished. We consider both short-term depression and facilitation. Interestingly, we find that a double inverse stocha . . .stic resonance (DISR), with two distinct wells centered at different presynaptic firing rates, can appear. © 2017 American Physical Society Daha fazlası Daha az

Simulation of Parkinsonian Basal nuclei with network motifs

Çalım, Ali | Özer, Mahmut | Uzuntarla, Muhammet

Proceedings | 2017 | 2017 25th Signal Processing and Communications Applications Conference, SIU 2017 , pp.83 - 92

Nowadays, neurodegenerative diseases which affect human life quite negatively with motor, cognitive and psychiatric disorders are becoming widespread. One of the most common neurodegenerative disorder is Parkinson's disease. Recent electrophysiological experiments have shown that Basal Ganglia, a special region in the midbrain, is related to Parkinsonism. Beta frequency oscillations, which are important symptoms of Parkinson's disease, emerge intensively in Globus Pallidus and Subtalamus nuclei. In this study, anatomical connections of Globus Pallidus and Subtalamus are constructed computationally, and the cellular properties that g . . .ive rise to emergence of beta oscillations are investigated. © 2017 IEEE Daha fazlası Daha az

Effects of autapse and channel blockage on firing regularity in a biological neuronal network

Uzun, Rukiye | Özer, Mahmut

Proceedings | 2017 | Istanbul University - Journal of Electrical and Electronics Engineering17 , pp.3069 - 3073

In this paper; the effects of autapse (a kind of self-synapse formed between the axon of the soma of a neuron and its own dendrites) and ion channel blockage on the firing regularity of a biological small-world neuronal network, consists of stochastic Hodgkin-Huxley neurons, are studied. In this study, it is assumed that all of the neurons on the network have a chemical autapse and a constant membrane area. Obtained results indicate that there are different effects of channel blockage and parameters of the autapse on the regularity of the network, thus on the temporal coherence of the network. It is found that the firing regularity . . .of the network is decreased with the sodium channel blockage while increased with potassium channel blockage. Besides, it is determined that regularity of the network augments with the conductance of the autapse Daha fazlası Daha az

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