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The Importance of Chert in Central Anatolia: Lessons from the Neolithic Assemblage at Çatalhöyük, Turkey

Nazaroff A.J. | Baysal A. | Çiftçi Y.

Article | 2013 | Geoarchaeology28 ( 4 ) , pp.340 - 362

This paper is a presentation of three sources of artifact-quality chert in Central Anatolia. A previous dearth of research focused on locating and characterizing such raw material sources has incorrectly colored our view of prehistoric economic practices. To remedy this situation, we have conducted a survey of various locales within Central Anatolia to test for the presence of artifact-quality materials. We make use of Individual Attribute Analysis (IAA) and Energy Dispersive X-ray Fluorescence (EDXRF) analysis to discriminate among these materials, and suggest their use by the Neolithic occupants of Çatalhöyük through similar analy . . .ses of artifactual materials. We argue that the presence and characterization of these new sources allows us to better understand the intricacies of Neolithic practices by illustrating the ways in which the consumption of these materials was variably entwined with the exploitation of other resources, as well as embedded within social relations outside of Central Anatolia. © 2013 Wiley Periodicals, Inc. Daha fazlası Daha az

Comparison of drillability and abrasivity properties of rocks [Kayaçlari{dotless}n delinebilirlik ve aşi{dotless}ndi{dotless}ri{dotless}ci{dotless}li{dotless}k özelliklerinin karşi{dotless}laşti{dotless}ri{dotless}lmasi{dotless}]

Çapik M. | Yilmaz A.O. | Yaşar S. | Yarali O. | Çavuşoglu I.

Conference Object | 2013 | 23rd International Mining Congress and Exhibition of Turkey, IMCET 20131 , pp.659 - 669

Drillability is defined as the penetration rate of a drill bit into the rock. Abrasion is broken off by the tools during the excavation of rocks. Different types of rock formations have different abrasiveness and hardness properties and that is significantly affected excavatability and drillability in the mechanical excavation systems. Because, abrasive rocks and hard rocks lead to an increase of the cost excavation, decrease of the penetration rate and atrophy of the cutter in a short time. This study was carried out in Hopa-Borcka (Artvin) Cankurtaran Highway Tunnel. Rock samples were obtained from Cankurtaran Tunnel at the changi . . .ng rock formations for the laboratory studies. The test samples were prepared at the appropriate size and quantity. Sievers J-miniature drill test (SJ) and the brittleness tests were carried out and for the drilling rate index values were calculated. Cerchar Abrasivity Index (CAI), Norway Abrasion Value (AV) and Bohme abrasion tests were carried out and for abrasiveness of rock properties. Uniaxial compressive strength, point load strength and Brazilian tensile strength tests were determined for the calculations mechanical properties of rock Daha fazlası Daha az

A preliminary geoengineering assessment of Bazda antique underground quarries in, Sanliurfa, Turkey

Agan, C. | Yesilnacar, M. I. | Genis, M. | Kulaksiz, S. | Ulusay, R. | Aydan, Oe | Yucel, M. D.


Geoengineering evaluation of man-made antique underground structures improves and provides important information on such structures. Harran City in, Sanliurfa Province of Turkey was constructed probably during Sumerian period BC 3000 (5000 years BP). The building stones consisting of limestones of Harran City were extracted from open-pit and underground quarries known as Bazda quarries. Bazda antique underground quarry pillars suffer some structural stability problems in terms of splitting of high pillars, roof falls, plane or wedge sliding and large sinkholes. The authors have initiated a collaborative integrated research program t . . .o map the antique underground quarries having working levels up to four floor, in-situ rock characterization, identification of stability problems, some geomechanical properties of surrounding rock. This paper describes the first preliminary studies on Bazda antique underground quarries and discusses its implications in modern geomechanics and geoengineering Daha fazlası Daha az

The influence of RET's on elementary and secondary grade teachers' views of scientific inquiry

Bahbah S. | Golden B.W. | Roseler K. | Elderle P. | Saka Y. | Shoutherland S.A.

Article | 2013 | International Education Studies6 ( 1 ) , pp.117 - 131

This study explores in-service elementary and secondary science teachers' conceptions of the Nature of Scientific Inquiry and the influence of participation in two different Research Experience for Teacher (RET) programs had on these conceptions. Participant teachers attended one of two six week RET programs in which they worked with scientists to engage in scientific inquiry. Before and after the RETs, teachers completed the Views of Scientific Inquiry (VOSI) questionnaire. Teachers' answers were analyzed to determine the degree of sophistication of their understanding of five facets of scientific inquiry. Both elementary and secon . . .dary teacher participants showed improvement in their understanding of nature of scientific inquiry as a result of program participation, and both programs were successful in supporting the development of inquiry conceptions, although secondary science teachers started and finished the RET's with a more sophisticated understandings of scientific inquiry. Areas of improvement for elementary teachers included the role of questions in science and the role subjectivity and creativity play in the processes of science, and for secondary teachers growth was seen in the role of questions, the relationship of data and evidence, the distinction of experiments and other means of investigations, and the varied methods of science. Implications of these results are discussed Daha fazlası Daha az

Warm and harsh parenting as mediators of the relation between maternal and adolescent emotion regulation

Saritaş D. | Grusec J.E. | Gençöz T.

Article | 2013 | Journal of Adolescence36 ( 6 ) , pp.1093 - 1101

Maternal hostility/rejection and warmth were considered as potential mediators of the relation between mothers' and adolescents' emotion regulation. Participants were first-year high school students living in Ankara, Turkey and their mothers (N=365). Scales assessing emotion regulation difficulties and maternal hostility/rejection and warmth were administered to both the adolescents and their mothers. Maternal hostility/rejection, but not warmth, mediated the relation between maternal and adolescent emotion regulation. For girls there was, additionally, a direct effect of maternal emotion regulation. The different roles played by pa . . .rental rejection and parental warmth in the development of adolescents' emotion regulation accord with arguments that socialization occurs in different domains and that rejection and warmth are not aspects of the same domain. © 2013 The Foundation for Professionals in Services for Adolescents Daha fazlası Daha az

The effects of zoledronic acid on mandibular fracture healing in an osteoporotic model: A stereological study

Sener I. | Bereket C. | Kosker H. | Turer A. | Tek M. | Kaplan S.

Article | 2013 | Journal of Craniofacial Surgery24 ( 4 ) , pp.1221 - 1224

The aim of this study was to evaluate the effect of zoledronic acid (ZA) in the ovariectomized rat on mandibular fracture. Corpus osteotomies were performed on the mandible of ovariectomized rats. Miniplates were placed on these rats, which were randomly divided into 4 groups. After 7 days, groups 3 and 4 were injected with 0.1 mg/kg ZA. Groups 1 and 2 were control groups, so they were injected 0.1 mg/kg saline solution. Animals in groups 1 and 3 were killed at 4 weeks, whereas groups 2 and 4 were killed 8 weeks after operation. The new bone volume of the fracture gap was examined stereologically. Although the difference was not sta . . .tistically significant compared with the other groups (groups 1 and 3), more bone formation was found in ZA-treated groups (groups 2 and 4) (P < 0.05). © 2013 by Mutaz B. Habal, MD Daha fazlası Daha az

Application of response surface methodology to extract yields from stinging nettle under supercritical ethanol conditions

Akalin M.K. | Karagöz S. | Akyüz M.

Article | 2013 | Journal of Supercritical Fluids84 , pp.164 - 172

Response surface methodology was employed using a central composite design of experiments to optimize experimental conditions for stinging nettle extract yields under supercritical ethanol conditions. The following independent variables were investigated: extraction temperature, extraction time and plant concentration. The most significant factor was found to be the extraction temperature. A correlation coefficient was estimated to be 0.94, which demonstrates the effectiveness of the model. The values of the parameters in optimized conditions for the stinging nettle extract yield included an extraction temperature of 335 C, an extra . . .ction time of 87 min, and a plant concentration of 9. A subsequent validation experiment was carried out at the optimal conditions. The validation experiment showed that the actual and predicted values for the stinging nettle extract yields were 45.3 and 42.7 wt%, respectively. The stinging nettle extracts consisted of a collection of compounds including fatty acid esters (FAE), phenols, indoles, and nitrogen containing compounds. © 2013 Elsevier B.V. All rights reserved Daha fazlası Daha az

Assessment of relationships between drilling rate index and mechanical properties of rocks

Yarali O. | Soyer E.

Article | 2013 | Tunnelling and Underground Space Technology33 , pp.46 - 53

This paper examines the relationships between drilling rate index (DRI) and some mechanical properties of rocks in order to evaluate the effect of strength and indexes of rock on rock drillability. For this purpose, some index properties (in situ Schmidt rebound hardness (SRH), Shore scleroscope hardness (SSH), and point load strength (PLS)) and strength properties (uniaxial compressive strength (UCS) and Brazilian tensile strength (BTS)) values of 32 sedimentary, igneous and metamorphic rock samples were determined. The relationships between DRI and both strength and indexes properties were evaluated using regression analysis and s . . .tatistical methods. As a result, decreasing linear relationships were found between DRI and uniaxial compressive strength, Schmidt rebound hardness, Shore scleroscope hardness, diametral and axial point load strength. © 2012 Elsevier Ltd Daha fazlası Daha az

Public awareness of testicular cancer and self-examination in Turkey: A multicenter study of Turkish Urooncology Society

Kuzgunbay B. | Yaycioglu O. | Soyupak B. | Kayis A.A. | Ayan S. | Yavascaoglu I. | Cal C.

Article | 2013 | Urologic Oncology: Seminars and Original Investigations31 ( 3 ) , pp.386 - 391

Background: Testicular self-examination is the easiest and cheapest way to scan testicular cancer. However, the public awareness about testicular self-examination is very low. We aimed to investigate the public awareness of Turkish people about testicular cancer and testicular self-examination. Methods: We performed a survey consisting of 10 questions concerning testicular cancer and testicular self-examination in 799 students in the first year of 12 different medical schools. Aiming for a common method of data collection, the questionnaires were administered to the students during a class just before the lesson started. The whole d . . .ata from all of the centers were pooled in a common data-base file. Results: Eighty-nine (11.1%) of the participants reported that they had knowledge about testicular cancer, but only 11 (1.4%) of them answered all the questions about testicular cancer correctly. Eight (1%) of the participants reported that they had been performing testicular self-examination routinely once a month. Four (0.5%) of them were both well informed about testicular cancer and had been performing testicular self-examination once a month as suggested. Conclusion: The present study showed that awareness on testicular cancer and testicular self-examination is very low and suggests a need for efforts in Turkey to increase public awareness and education. © 2013 Elsevier Inc Daha fazlası Daha az

Scapania gracilis Lindb. (Hepaticae, Scapaniaceae), new to bryophyte flora of Turkey

Ezer T. | Kara R. | Alataş M.

Article | 2013 | Folia Cryptogamica Estonica50 , pp.117 - 119

Scapania gracilis Lindb. is a hygro- to mesophytic liverwort species which is reported for the first time from Turkey. The species is described from material collected from the north-west Anatolia (Sakarya) which has very warm summers and mild winters with high annual rainfall (800-1000 mm) in Marmara region and very humid conditions. Turkish plants are described and illustrated.

Mathematical modelling, analysis and numerical simulations for the influence of heat shock proteins on tumour invasion

Meral G. | Surulescu C.

Article | 2013 | Journal of Mathematical Analysis and Applications408 ( 2 ) , pp.597 - 614

Invasion is a key property of tumour cells for building metastasis. A class of functionally related proteins called heat shock proteins (HSPs), the expression of which is increased when cells are exposed to elevated temperatures or other stress, play an important role in the invasion. In this paper we develop a mathematical model focusing on the effect of HSPs on the tumour cell migration. The resulting multiscale setting accounts both for the microscopic, intracellular level on which these proteins are acting and for the macroscopic level of the cell population. We prove the local existence of a unique positive solution and perform . . . numerical simulations in order to illustrate the behaviour of cancer cells w.r.t. the fibre density of the tissue and the matrix degrading enzymes, along with the effect of HSPs. © 2013 Elsevier Ltd Daha fazlası Daha az

Herceptin-decorated salinomycin-loaded nanoparticles for breast tumor targeting

Aydin R.S.T.

Article | 2013 | Journal of Biomedical Materials Research - Part A101 A ( 5 ) , pp.1405 - 1415

The use of conventional chemotherapeutic drugs was emerged as challenging for breast cancer therapy, because breast cancer stem cells cannot be destroyed due to their great nature of drug resistance. In this study, a novel nanoparticulate system of Herceptin (HER)-immobilized salinomycin (SAL)-encapsulated poly(lactic-co-glycolic acid) (PLGA) (HER-SAL-PLGA) nanoparticles were constructed and investigated for breast cancer targeting. SAL-encapsulated PLGA nanoparticles were characterized for their particle size, morphology, structural and thermal properties, and drug-encapsulation efficiency. HER-SAL-PLGA nanoparticles were character . . .ized via particle size, surface chemistry, and herceptin-immobilization efficiency. In vitro release studies were performed for both nontargeting and targeting SAL-PLGA nanoparticles, which demonstrated a controlled release of SAL from nanoparticles. Cellular uptake of the HER-SAL-PLGA nanoparticles was assessed by fluorescence and optical microscopy and flow cytometry, which showed that the HER-SAL-PLGA nanoparticles were successfully uptaken by MCF7 cells. In conclusion, this novel drug-delivery system, HER-SAL-PLGA, was suggested as a promising targeting system for breast cancer therapy. © 2012 Wiley Periodicals, Inc Daha fazlası Daha az

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