Üstündag G. | Kuloglu Z. | Kirbaş N. | Kansu A.

Article | 2010 | Turkish Journal of Gastroenterology21 ( 4 ) , pp.360 - 364

Background/aims: In the present study, we aimed to investigate if partially hydrolyzed guar gum (PHGG) can be used safely as a fiber source for treatment of constipation in children and to compare its success with the most commonly used osmotic laxative, lactulose. Methods: A randomized prospective controlled study on 61 patients (partially hydrolyzed guar gum group, n: 31; lactulose group, n: 30) was performed. Patients were given lactulose or partially hydrolyzed guar gum for four weeks. Using a standardized bowel diary, defecation frequency, stool consistency, and presence of flatulence and abdominal pain were recorded. Family qu . . .estionnaires about the success, safety and side effect profile of both treatment arms were also obtained. Results: No significant differences were found in the baseline daily fiber (fruits and vegetables) intake between the two groups. Bowel movement frequency per week and stool consistency improved significantly in both treatment groups ( Daha fazlası Daha az