Protective role of alpha-tocopherol and caffeic acid phenethyl ester on ischemia-reperfusion injury via nitric oxide and myeloperoxidase in rat kidneys

Gurel, A | Armutcu, F | Sahin, S | Sogut, S | Ozyurt, H | Gulec, M | Kutlu, NO

Article | 2004 | CLINICA CHIMICA ACTA339 ( 01.Feb ) , pp.33 - 41

Background: The aim of this study was to determine the acute effects of antioxidant caffeic acid phenethyl ester (CAPE) and alpha-tocopherol (vitamin E) on nitric oxide (NO) production, neutrophil infiltration, and antioxidant enzyme activities on an in vivo model of renal ischemia-reperfusion injury. Methods: Rats were divided into five equal groups each consisting six rats: sham operation, ischemia, ischemia-reperfusion (I/R), I/R plus CAPE, and I/R plus vitamin E groups. CAPE or vitamin E was administered intraperitoneally before reperfusion. After experimental procedure, rats were sacrificed and both ipsilateral and contralatera . . .l kidneys were removed and prepared for NO concentrations, myeloperoxidase (MPO), catalase (CAT) and superoxide dismutase (SOD) activities. Results: Acute administration of vitamin E decreased NO concentrations in both ipsilateral and contralateral renal tissues compared to I/R group. SOD activity was increased in I/R and I/R + CAPE groups compared to sham operation group. The most prominent results were encountered in MPO activities, which did not change in contralateral kidneys in both ischemia and I/R groups. There was a significant decrease in ipsilateral MPO activity in ischemia group and a significant increase in I/R group compared to sham operation group. Pretreatment with intraperitoneal CAPE significantly diminished the tissue MPO activity indicating the prevention of the neutrophil sequestration into the kidney. Conclusion: There is a role for CAPE in attenuation in renal damage after I/R injury of the kidney, in part at least by inhibition of neutrophil sequestration. (C) 2003 Elsevier B.V. All rights reserved Daha fazlası Daha az

Cardiac autonomic activity in panic disorder patients

Atasoy, N | Aydin, M | Davutoglu, R | Konuk, N | Simsekyilmaz, O | Atik, L

Conference Object | 2004 | EUROPEAN NEUROPSYCHOPHARMACOLOGY14 , pp.33 - 41

17th Congress of the European-College-of-Neuropsychopharmacology -- OCT 09-13, 2004 -- Stockholm, SWEDEN WOS: 000225460400410

Oxygen transfer in flow around and over stones placed in a laboratory flume

Cokgor, S | Kucukali, S

Article | 2004 | ECOLOGICAL ENGINEERING23 ( 3 ) , pp.205 - 219

Oxygen transfer around stones located within a stream was studied in a laboratory-recirculating flume. The present study focused on two main points: first, it examined the change in dissolved oxygen (DO) levels between a section upstream and a section downstream of the stones and second, it documented the DO distribution around the stones. The presence of stones increased the DO transfer efficiency by 0-0.60 in the flume. Therefore stones could be used in river reclamation projects to provide aeration. The experiments with two stones resulted in higher DO transfer efficiencies such as 0.43 compared to those obtained in the case of a . . . single stone with the highest values of 0.26. The relative depth of the flow compared to the height of the stone(s) is an important parameter characterizing the DO ratios. When the stone(s) was submerged, there were marginal to no changes in the level of DO in the flow. The changes in DO levels were substantial when the stones were piercing through the water surface. Some of the DO improvements obtained by including the stone(s) were comparable to those reported in the literature when man-made structures were placed in streams. (C) 2004 Elsevier B.V. All rights reserved Daha fazlası Daha az

The synthesis and crystal structures of di-mu-dichloro-bis{[N,N-dimethylaminobenzyl-C-1,N]dipalladium(II)} and of the Cocrystals of {chloro-(triphenylphosphino)-bis[N,N-dimethylaminobenzyl-C-1,N]palladium(II) and {trans-bis(triphenylphosphino)-chloro[N,N-dimethylaminobenzyl-C]palladium(II)}

Mentes, A | Kemmitt, RDW | Fawcett, J | Russell, DR

Article | 2004 | JOURNAL OF MOLECULAR STRUCTURE693 ( 01.Mar ) , pp.241 - 246

The X-ray crystal structures of cyclopalladated complexes are reported. Reaction of {[Pd(dmba)(mu-Cl)](2)}, (1), (dmba = N(CH3)(2)-CH2C6H5) with triphenylphosphine gave crystals containing {chloro-(triphenylphosphino)-bis[N,N-dimethylaminobenzyl-C-1,N] palladium(II)} (2a) and {trans-bis(triphenylphosphino)-chloro-[N,N-dimethylaminozyl-C]palladium(II)} (2b). Complex (1) crystallises in the space group P2(1)/c with a = 7.849(l) Angstrom, b = 15.635(3) Angstrom, c = 8.352(l) Angstrom, beta = 109.29degrees, and D-calc = 1.895 g cm(-3) for Z = 2. Complexes (2a) and (2b) crystallize together in the space group P2(1)/n with a = 9.964(2) An . . .gstrom, b = 34.228(5) Angstrom, c = 18.127(3) Angstrom, beta = 91.91 degrees, and D-calc = 1.439 g cm(-3). (C) 2004 Elsevier B.V. All rights reserved Daha fazlası Daha az

Design optimisation of atypical strip-wound toroidal core using genetic algorithms

Tutkun, N | Moses, AJ

Article | 2004 | JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS277 ( 01.Feb ) , pp.216 - 220

The genetic algorithm (GA) method has recently been a very useful tool for the design optimisation of switching electromagnetic devices such as transformers built from toroidal cores. In these types of cores, inner and outer diameters, primary and secondary number of turns, the strip width are influential parameters on power loss increase under sinusoidal and non-sinusoidal excitations. The design optimisation of magnetic cores using conventional methods requires the solutions of a set of non-linear equations and well-experienced engineers. However, an optimal design of the cores can be achieved using a simple GA design. In this pap . . .er, the GA method has been used for the optimal design of a typical strip-wound toroidal core widely employed in building a magnetic circuit of a transformer, various switching circuits, etc. The results show outstanding indications in terms of minimisation of power loss and cost of building material with respect to conventional methods. (C) 2003 Elsevier B.V. All rights reserved Daha fazlası Daha az

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