Hocagil, Abdullah Cuneyt | Hocagil, Hilal

Makale | 2018 | EURASIAN JOURNAL OF EMERGENCY MEDICINE17 ( 3 ) , pp.118 - 121

WOS: 000446896600009

Sengoz, Mihribanen | Piskin, Nihal | Aydemir, Hande | Kokturk, Furuzan | Tekin, Ishak Ozel | Celebi, Goven | Atakent, Deniz

Makale | 2019 | KLIMIK JOURNAL32 ( 1 ) , pp.46 - 51

Objective: Health care workers are exposed to many infectious agents when compared with general population. Immunization to vaccine-preventable diseases is an important part of infection control among health care workers, both for their own health and to prevent the spread of infections. The aim of this study is to detect the immune status of health care workers of our hospital to measles, mumps, rubella (MMR) and varicella and to define an appropriate vaccination program and also to analyze the cost efficiency of pre-vaccination screening. Methods: This study was conducted at Bulent Ecevit University Hospital between March 2014 and . . . January 2015. The following data were recorded for each participant: age, gender, profession, department, duration of employment, childhood residence location, history of MMR and varicella, and status of vaccinations. The specific IgG antibodies were screened by immunosorbent enzyme-linked assay. Results: 184 health care workers participated in the study. 61.2% were female, and 38.8% were male. The mean age was 32.43 +/- 6.4. The serologic test results revealed that 92.2% of the health care workers were immune to measles, 98.2% were immune to rubella, 94% were immune to mumps and 94.3% were immune to varicella. The validity of the medical history of participants were high for mumps and measles (81.6% and 80.5%, respectively) and low for rubella (43.4%). The positive predictive values for the history of rubella, mumps, varicella and measles were 98.9%, 97.5% and 96.9%, 95.6%, respectively. Cost efficiency analysis showed that the cost of vaccination without screening was more expensive for varicella and MMR (cost difference 18 253 Turkish Lira and 1432 Turkish Lira, respectively) Our findings support that a negative medical history or serological screening before vaccination is cost effective especially for varicella. Conclusions: In conclusion, immune status of health care workers who worked in high-risk departments should be determined by serologic tests and susceptible health care workers must be vaccinated Daha fazlası Daha az

Oral, Keziban | Akan, Mert | Ozkardesler, Sevda | Boztas, Nilay | Ergur, Bekir Ugur | Guneli, Mehmet Ensari | Olguner, Cimen

Makale | 2018 | TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION46 ( 6 ) , pp.453 - 461

Objective: One of the methods that can be used to prevent ischaemia reperfusion (IR) injury is ischaemic preconditioning. The aim of this study was to evaluate and compare the effects of remote and direct ischaemic preconditioning (RIPC and DIPC) histopathologically in the rat renal IR injury model. Methods: After obtaining an approval from the Dokuz Eylul University School of Medicine Ethics Committee, 28 Wistar Albino male rats were divided into four groups. In Group I (Sham, n=7), laparotomy and left renal pedicle dissection were performed, but nothing else was done. In Group II (IR, n=7), after 45 minutes of left renal pedicle o . . .cclusion, reperfusion lasting 4 hours was performed. In Group III (DIPC+IR, n=7), after four cycles of ischaemic preconditioning applied to the left kidney, renal IR was performed. In Group IV (RIPC+IR, n=7), after three cycles of ischaemic preconditioning applied to the left hind leg, renal IR was performed. All rats were sacrificed, and the left kidney was processed for conventional histopathology. Results: The histopathological injury score of the kidney was significantly lower in the sham group compared with the other groups ( Daha fazlası Daha az

Bolat M.S. | Bakirtaş M. | Firat F. | Akdeniz E. | Çinar Ö. | Erdemir F.

Makale | 2019 | Turkish Journal of Urology45 ( 2 ) , pp.91 - 96

Objective: A debate is open on the effects of lipid-lowering drugs on sexual function. We aimed to investigate the effect of atorvastatin use on penile intracavernosal pressure (ICP) and cavernosal morphology. Material and methods: Fourteen mature male Sprague-Dawley-rats were randomly assigned to either the control group (which received standard food and water ad libitum) or the atorvastatin group (which received standard food, water, and statin) for twelwe weeks. At the end of the study, ICPs were measured with cavernosometry. Penectomy specimens were histologically examined. Results: The following mean values were obtained for th . . .e control and atorvastatin groups, respectively: pre-study body weights (350±16.9 g and 331.4±24.9 g); post-study body weights (356±18 g and 368±22.5 g (p>0.05); ICPs at 5 V (5.96±5.16 mmHg and 2.11±1.22 mmHg (p=0.07)); ICPs at 10 V (18.28±14.1 mmHg and 5.56±5.58 mmHg) (p=0.09); testosterone (1.23±0.78 and 0.78±0.58 mmol/dL) (p=0.39); blood glucose (151±22 mg/dL and 168.6±16.2 mg/dL) (p=0.12); triglyceride (93.4±19.8 mg/dL and 52.1±18.6 mg/ dL) (p=0.01); total cholesterol (50.2±7.2 mg/dL and 47.7±6.6 mg/dL) (p=0.51); and low-density lipoprotein (LDL) cholesterol (10.0±4.4 mg/dL and 3.5±2.1 mg/dL) (p=0.01). The mean collagen thickness was similar (p=0.09); but the mean elastin thickness increased in the atorvastatin group (p=0.01). Conclusion: The present study showed that the use of atorvastatin reduced the intracavernosal pressure in 10 V stimulation, and minimally decreased testosterone levels in rats, within a short period of time. When statin treatment is considered for its protective properties on cardiovascular system or for its lipid-lowering effect. It should be kept in mind that atorvastatin may also adversely contribute to erectile dysfunction. © 2019 by Turkish Association of Urology Daha fazlası Daha az

Altinsoy, Bulent | Yalcinsoy, Murat | Unver, Edhem | Gungor, Sinem | Mihmanli, Aydanur | Akkaya, Esen

Makale | 2016 | ISTANBUL MEDICAL JOURNAL17 ( 2 ) , pp.59 - 63

Objective: To evaluate the diagnostic performance of adenosine deaminase (ADA) levels in patients with exudative lymphocytic pleurisy for the differential diagnosis of tuberculous pleurisy (TBP) and malignant pleural effusion (MPE). Methods: Data on patients with exudative lymphocytic pleurisy were retrospectively analyzed. The study population comprised 54 patients. Thirty-seven were diagnosed with TBP and 17 were diagnosed with MPE. Results: Significant differences were determined in terms of age and ADA, total protein, albumin, and LDH levels between the TBP and MPE groups. The optimal cut-off value of ADA levels was 35.1 U/L for . . . diagnosing TBP. Sensitivity and specificity were 92% and 100%, respectively. Logistic regression analysis was performed to assess independent variables associated with TBP. Independent predictive factors in the model were ADA (OR: 1.21, 95% CI: 1.06-1.39, p=0.006)], and (OR: 0.92, 95% CI: 0.84-1.00, p=0.052)]. The AUC value by the regression equation was 0.979 (p 13.51 and > 35.1) for each age range were found in all, but one, TBP patients. Conclusion: ADA levels are useful for the diagnosis of TBP in cases where pleural biopsy cannot be performed or that are inconclusive in making a diagnosis of TBP. In this group, reducing the conventional cut-off value and/or performing an age-based approach seems to improve the diagnostic performance of ADA levels Daha fazlası Daha az

Baldane, Suleyman | Korkmaz, Huseyin | Ipekci, Suleyman Hilmi | Sozen, Mehmet | Abusoglu, Sedat | Akar, Tarik | Unlu, Ali

Makale | 2017 | JOURNAL OF ACADEMIC RESEARCH IN MEDICINE-JAREM7 ( 3 ) , pp.132 - 134

Objective: Increased asymmetric dimethylarginine (ADMA) levels are associated with reduced nitric oxide (NO) levels in many systems, particularly the cardiovascular system, and cause adverse effects. The objective of this study is to evaluate the effect of eradication therapy in patients infected with Helicobacter pylori (H. pylori) on the serum level of ADMA and other metabolic products of methylarginine. Methods: Patients who were found positive both in urea breath tests and stool antigen tests were considered to have H. pylori infection. These patients received eradication therapy for 14 days (twice daily pantoprazole 40 mg, twic . . .e daily amoxicillin 1000 mg, and twice daily clarithromycin 500 mg). Blood samples were taken to measure serum ADMA, symmetric dimethylarginine (SDMA), and N-monomethyl-Larginine (L-NMMA) levels before eradication therapy and 3 months after the therapy for patients for whom eradication was achieved. Results: A total of 23 of the 45 patients included in the study were female, whereas 22 were male. The mean age of the patients was 32.4 +/- 8 years. Significant reductions in the serum ADMA, SDMA, and L-NMMA levels of the patients were observed post-eradication therapy versus pre-eradication therapy. Conclusion: This study demonstrated significant reductions in serum ADMA, SDMA, and L-NMMA levels with H. pylori eradication. Further extensive long-term studies are needed to evaluate the positive effects that reduced serum ADMA, SDMA, and L-NMMA levels after H. pylori eradication can have on all systems, particularly the cardiovascular system Daha fazlası Daha az

Unal, Emre | Onur, Mehmet Ruhi | Balci, Sinan | Gormez, Aysegul | Akpinar, Erhan | Boge, Medine

Makale | 2017 | DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY23 ( 1 ) , pp.5 - 9

PURPOSE We aimed to evaluate the CT findings of stercoral colitis (SC). METHODS Forty-one patients diagnosed with SC between February 2006 and April 2015 were retrospectively reviewed. RESULTS Rectosigmoid colon was the most frequently involved segment (100%, n= 41). CT findings can be summarized as follows: dilatation >6 cm and wall thickening > 3 mm of the affected colon segment (100%, n= 41), pericolonic fat stranding (100%, n= 41), mucosal discontinuity (14.6 %, n= 6), presence of free air (14.6%, n= 6), free fluid (9.7%, n= 4), and pericolonic abscess (2.4%, n= 1). The sign most related with mortality was the length of the affe . . .cted colon segment > 40 cm. CONCLUSION CT has an important role in SC, since life-threatening complications can be easily revealed by this imaging modality. Increased length of involved colon segment (> 40 cm) is more likely to be associated with mortality Daha fazlası Daha az

Gunes, Aygul | Yildiz, Demet | Pekel, Nilufer Buyukkoyuncu | Seferoglu, Meral | Parmak, Neslihan | Yazgan, Serpil | Altintas, Ozge

Makale | 2018 | BEZMIALEM SCIENCE6 ( 4 ) , pp.317 - 319

Malignancy, immunosuppressive drug use, and diabetes mellitus (DM) are defined as risk factors for herpes zoster. A 58-year-old male patient with the diagnosis of DM was admitted to the emergency room with the complaints of double vision. His neurological examination revealed under activity of the right lateral rectus muscle and hypoactive deep tendon reflexes. In this report, we discuss a rare case of isolated abducens nerve palsy that occurred after postviral infection in the patient.

Ozcetin, Mustafa | Karaci, Mehmet | Toroslu, Ertug | Edebali, Nurullah

Makale | 2016 | TURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS51 ( 3 ) , pp.162 - 165

Pituitary adenomas usually arise from the anterior lobe of the pituitary gland and are manifested with hormonal disorders or mass effect. Mass effect usually occurs in nonfunctional tumors. Pituitary adenomas may be manifested with visual field defects or rarely in the form of total oculomotor palsy. Visual field defect is most frequently in the form of bitemporal hemianopsia and superior temporal defect. Sudden loss of vision, papilledema and ophthalmoplegia may be observed. Pituitary apoplexy is defined as an acute clinical syndrome characterized with headache, vomiting, loss of vision, ophthalmoplegia and clouding of consciousnes . . .s. The problem leading to pituitary apoplexy may be decreased blood supply in the adenoma and hemorrhage following this decrease or hemorrhage alone. In this article, we present a patient who presented with fever, vomiting and sudden loss of vision and limited outward gaze in the left eye following trauma and who was found to have pituitary macroadenoma causing compression of the optic chiasma and optic nerve on the left side on cranial and pituitary magnetic resonance imaging Daha fazlası Daha az

Arikan I.I. | Barut A. | Arikan D. | Harma M. | Harma M.I. | Bozkurt S.

Makale | 2010 | Journal of the Turkish German Gynecology Association11 ( 3 ) , pp.149 - 151

Objective: In this study, we investigated whether serum androgen levels and endometrial thickness differed in obese and non-obese women. Material and Methods: Thirtytwo non-obese (BMI 5 mm had significant pathology. Conclusion: These results suggest that obesity may be a risk factor for endometrial carcinoma and other pathologies in post-menopausal women through an action on androgen concentrations.

Kaya, Selcuk | Aktas, Seyhan | Senbayrak, Seniha | Tekin, Recep | Oztoprak, Nefise | Aksoy, Firdevs | Firat, Pinar

Makale | 2016 | EURASIAN JOURNAL OF MEDICINE48 ( 1 ) , pp.24 - 28

WOS: 000373481300007 PubMed: 27026760

Kocak, Cemal | Kurcer, Mehmet Ali | Arikan, Inan Ilker

Makale | 2015 | ISTANBUL MEDICAL JOURNAL16 ( 4 ) , pp.133 - 136

Objective: Smoking in pregnancy and postpartum period causes serious healthy risks for fetuses, newborns, and children. The purpose of this study was to determine the prevalence of smoking and associated socio-demographic factors and knowledge, attitude levels, and behaviors of pregnant smokers. Methods: A descriptive study was performed on 335 pregnant women who were admitted to our clinic between March 1 and April 30, 2014. A questionnaire prepared by researchers comprising 24 questions was applied to eligible women. Statistical analysis was performed using SPSS 19 software program. Descriptive statistical data are presented as fr . . .equencies, and measurements are presented as mean +/- standard deviation. Chi-square test was used for comparison between categorical variables. Mann-Whitney U test and Kruskal-Wallis analysis of variance were used for comparisons between paired groups. Results: A total of 20.5% of pregnant women smoked throughout pregnancy. Education and income status of pregnant women did not have a significant association with smoking during pregnancy (p=0.172 and p=0.203, respectively). Smoking status was compared with pregnancy, breastfeeding, and total knowledge scores. While a significant difference did not exist between pregnancy and total knowledge scores (p=0.126, p=0.051), knowledge scores of breastfeeding was significantly lower in smoking women (p=0.031). Education status and knowledge scores were compared. Each of the three knowledge scores was higher in women with higher education levels (p=0.003, p=0.000, and p=0.001). Conclusion: Smoking during pregnancy is a major health problem. Control frequency should be increased for pregnant smokers and for their babies as well as to aid in the early diagnosis of potential problems. Doctors, nurses, and midwives should remind patients who quit smoking during pregnancy that they should take professional help to not start smoking again in the postpartum period Daha fazlası Daha az