Yavuz N. | Karabad T. | Çabuk M. | Sayin M.R. | Aktop Z. | Gursoy Y.C.

Makale | 2015 | Turkiye Klinikleri Cardiovascular Sciences27 ( 1 ) , pp.32 - 35

Behçet disease is a chronic, inflammatory, multisystemic vasculitis mainly characterized by orogenital ulcers. It is mainly observed in Turkey, other Mediterranean areas, and Japan. Viral, bacterial, genetic, immunologic, and environmental factors have been implicated in the pathogenesis of the disease. Although disease is multisystemic, cardiac involvement is rare and often associated with poor prognosis. Hypercoagulopathy is one of the important manifestation of the Behçet disease. Thromboembolic events such as myocardial infarction, stroke and pulmonary embolism risk is higher in patients with Behçet compared to normal population . . .. Right ventricular thrombus is a quite rare. In this paper we present a 26-year-old male patient who presented with pulmonary embolism and was subsequently diagnosed with a right ventricular thrombus and completely recovered after treatment. We also discussed diagnostic and therapeutic options. © 2015 by Turkiye Klinikleri Daha fazlası Daha az

Akdemir M.O. | Sayin M.R. | Armut M. | Akpinar I. | Ugurbas S.H.

Makale | 2014 | Eye (Basingstoke)28 ( 5 ) , pp.594 - 599

AimsTo determine whether pseudoexfoliation syndrome is associated with coronary artery ectasia or not.MethodsThis cross-sectional study was undertaken at Bulent Ecevit University's Ophthalmology Department with the participation of the Cardiology Department. Eighty consecutive patients who underwent coronary angiography and were classified into two groups - those diagnosed with a normal coronary artery (n=40) and those diagnosed with coronary artery ectasia (n=40) - were included in the study. Pseudoexfoliation was diagnosed if typical exfoliation material was found to be present on the anterior surface of the lens, the iris, or at . . .the pupillary border on slit-lamp examination. Age, sex, presence of pseudoexfoliation material, hypertension, diabetes mellitus, hyperlipidemia rates, cigarette smoking history, and family history of coronary artery disease were compared between the two groups. The continuous variables were compared by using the independent sample t-test or the Mann-Whitney U-test, and the categorical variables were compared using Pearson's ? 2 -test or Fisher's Exact ? 2 -test for the two groups.ResultsThere was no difference in demographic data of both groups. The presence of pseudoexfoliation material was more common in patients with coronary ectasia compared with controls (n=21 (52.5%) vs n=8 (20%), P=0.005). In all patients, there was a higher glaucoma rate in the patients with pseudoexfoliation syndrome n=7 (24.1%), 6 CAE (+), 1 CAE (-) than in the normal patients n=2 (3.9%), 2 CAE (-) (P=0.010). ConclusionsIn this study, we found a possible association of pseudoexfoliation and coronary artery ectasia. Coronary artery ectasia patients had higher prevalence of pseudoexfoliation. © 2014 Macmillan Publishers Limited All rights reserved Daha fazlası Daha az

Magden K. | Hur E. | Yildiz G. | Kose S.B. | Bicak S. | Yildirim I. | Sayin M.R.

Makale | 2013 | Renal Failure35 ( 10 ) , pp.1344 - 1347

Introduction: Overhydration is the main contributory factor of left ventricular hypertrophy and closely associated with cardiovascular events in end stage renal disease (ESRD) patients. The aim of this prospective-study was to investigate the impact of strict salt and volume control on hypertension and cardiac condition in ESRD patients. Methods: A total of 12 peritoneal dialysis (PD) and 15 prevalent hemodialysis (HD) patients were enrolled. All patients either PD or HD were allocated to intervention of strict salt restriction according to basal hydration state of empty abdomen in PD and midweek predialysis HD which were estimated . . .by body composition monitor (BCM) and echocardiography. Results: Mean ages were 48.3±16.7 years for PD, and 48.8±18 for HD patients. Extracellular water/height was 10.04±2.70 and 10.39±1.53L/m in PD and HD groups. Systolic blood pressures decreased in PD and HD from 133.1±28 and 147.3±28.5 to 114.8±16.5 and 119.3±12.1mmHg, respectively, (p0.05). LVMI and LAI were not increased in both groups. Conclusion: Strict salt and volume control in ESRD patients after assessment of hydration status with either using BCM or echocardiography provides better management of volume control leading to more precise cardiovascular protection. © 2013 Informa Healthcare USA, Inc Daha fazlası Daha az

Sayin M.R. | Akpinar I. | Demirtaş A.O.

Makale | 2013 | Turkish Journal of Thoracic and Cardiovascular Surgery21 ( 3 ) , pp.868 - 869

[No abstract available]

Sayin M.R. | Akpinar I. | Çetiner M.A. | Karabag T.

Mektup | 2013 | Anadolu Kardiyoloji Dergisi13 ( 6 ) , pp.616 - 618

[No abstract available]

Karabag T. | Aydin M. | Dogan S.M. | Koca R. | Buyukuysal C. | Sayin M.R. | Yavuz N.

Makale | 2012 | European Heart Journal Cardiovascular Imaging13 ( 3 ) , pp.251 - 256

Aims: To investigate the atrial electromechanical delay (EMD) duration that is a non-invasive predictor of atrial fibrillation (AF) in patients with Behcet's disease (BD). Methods and results: Thirty-eight Behcet's patients (24 females, 14 males; mean age: 43.6 ± 10.3 years) who were being followed in the dermatology or internal medicine department and 29 demographically matched controls (13 females, 16 males; mean: age 42.6 ± 11.1 years) were included in the study. The inclusion criteria were recurrent oral ulcerations and two of the following features: recurrent genital ulceration, eye lesions, skin lesions or positive pathergy sk . . .in test for Behcet's group. Using tissue Doppler imaging, atrial electromechanical coupling [time interval from the onset of P wave on surface electrocardiogram to the beginning of A wave interval with tissue Doppler echocardiography (PA)] were measured from the lateral mitral annulus (PA lateral), septal mitral annulus (PA septum), and right ventricular tricuspid annulus (PA tricuspid). The mean disease duration was 10.5 ± 7.7 years. The inter-atrial and intra-atrial EMD were significantly higher in the Behcet group than those in the controls (19.8 ± 8.2 vs. 13.1 ± 4.4 ms, P = 0.001; 11.5 ± 7.4 vs. 6.9 ± 3.7 ms, P = 0.02; respectively). The left atrial EMD was similar in both of the groups. However, the P max and PWD values were significantly higher in the BD group compared with those in the controls (120.5 ± 10.1 vs. 112.1 ± 5.9 ms, P < 0.0001; 44.9 ± 10.7 vs. 28.4 ± 5.9 ms, P < 0.0001; respectively). Conclusion: Atrial electromechanical conduction times were increased in the BD patients compared with those in the controls. The tendency of BD patients to go into AF can be easily and non-invasively detected using tissue Doppler echocardiography. These findings may be indicators for subclinical cardiac involvement. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2011 Daha fazlası Daha az

Sayin M.R. | Karabag T. | Dogan S.M. | Akpinar I. | Aydin M.

Makale | 2012 | Wiener Klinische Wochenschrift124 ( 07.Aug ) , pp.278 - 281

We herein present a case of a 76-year-old male patient presented with transient ST segment elevation and left bundle branch block caused by mad-honey poisoning. © Springer-Verlag Wien 2012.

Sayin M.R.

Mektup | 2013 | Internal Medicine52 ( 6 ) , pp.278 - 281

[No abstract available]

Sayin M.R. | Aydin M. | Dogan S.M. | Karabag T. | Cetiner M.A. | Aktop Z.

Makale | 2013 | Herz38 ( 3 ) , pp.299 - 305

OBJECTIVES: The aim of this study was to compare the effects of the new generation ß-blocker anti-hypertensive drugs carvedilol and nebivolol on aortic elastic properties which are important indicators of hypertension-related morbidity and mortality.METHODS: A total of 50 patients who had been diagnosed with stage 1 hypertension according to the Joint National Committee (JNC) VII criteria and who had not received any anti-hypertensive treatment were enrolled in this study. Patients were randomized to receive either 25 mg/day carvedilol (n=25) or 5 mg/day nebivolol (n=25) for 3 months at the beginning of the study. Three patients (1 . . .in the carvedilol group, 2 in the nebivolol group) who did not attend 3 month follow-up measurements were excluded from the study. The study was completed with 47 patients (25 women; mean age: 49 ± 9 years). The aortic elastic parameters such as aortic strain (AS), aortic distensibility (AD), and aortic stiffness index (ASI) were measured by echocardiography.RESULTS: Carvedilol and nebivolol provided a similar decline in both systolic and diastolic blood pressures (-12/-7 mmHg, Daha fazlası Daha az

Gudul N.E. | Karabag T. | Sayin M.R. | Bayraktaroglu T. | Aydin M.

Makale | 2017 | Korean Journal of Internal Medicine32 ( 2 ) , pp.286 - 294

Background/Aims: The aim of this study was to investigate atrial conduction times and left atrial mechanical functions, the noninvasive predictors of atrial fibrillation, in prediabetic patients with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). Methods: Study included 59 patients (23 males, 36 females; mean age 52.5 ± 10.6 years) diagnosed with IFG or IGT by the American Diabetes Association criteria, and 43 healthy adults (22 males, 21 females; mean age 48.5 ± 12.1 years). Conventional and tissue Doppler echocardiography were performed. The electromechanical delay parameters were measured from the onset of t . . .he P wave on the surface electrocardiogram to the onset of the atrial systolic wave on tissue Doppler imaging from septum, lateral, and right ventricular annuli. The left atrial volumes were calculated by the disk method. Left atrial mechanical functions were calculated. Results: The mitral E/A and E’/A’ ratios measured from the lateral and septal annuli were significantly lower in the prediabetics compared to the controls. The interatrial and left atrial electromechanical delay were significantly longer in prediabetic group compared to the controls. Left atrial active emptying volume (LAAEV) and fraction (LAAEF) were significantly higher in the prediabetics than the controls. LAAEV and LAAEF were significantly correlated with E/A, lateral and septal E’/A’. Conclusions: In the prediabetic patients, the atrial conduction times and P wave dispersion on surface electrocardiographic were longer before the development of overt diabetes. In addition, the left atrial mechanical functions were impaired secondary to a deterioration in the diastolic functions in the prediabetic patients. © 2017 The Korean Association of Internal Medicine Daha fazlası Daha az

Sayin M.R. | Akpinar I. | Karabag T. | Dogan S.M. | Aydin M.

Makale | 2013 | Journal of Cardiology Cases8 ( 1 ) , pp.286 - 294

Dual left anterior descending coronary artery (LAD) is a rare coronary anomaly and is divided into six subgroups in the literature according to the origin and course of the short and long branches of the anomalous artery. We present two distinct cases of dual LAD which are distinguished by two branches of equal length from their counterparts in the literature. Learning objective: In our cases a novel dual LAD variant is presented with two main branches of equal length and reaches the cardiac apex. Cardiologists and cardiovascular surgeons should be aware of these variants to avoid misinterpretation of coronary angiography and intrao . . .perative complications. © 2013 Japanese College of Cardiology Daha fazlası Daha az

Sayin M.R. | Altuntas M. | Aktop Z. | Oz I.I. | Yavuz N. | Akpinar I. | Sagatli E.

Makale | 2015 | Chinese Medical Journal128 ( 16 ) , pp.2141 - 2146

Background: Obstructive sleep apnea syndrome (OSAS) is a disease with increasing prevalence, which is mainly characterized by increased cardiopulmonary mortality and morbidity. It is well-known that OSAS patients have increased prevalence of cardiovascular diseases including coronary heart disease, heart failure, and arrhythmias. The aim of this study was to evaluate the presence of prolonged and fragmented QRS complexes, which have previously been associated with cardiovascular mortality, in OSAS patients. Methods: Our study included 51 patients (mean age 41.6 ± 10.1 years) who were recently diagnosed with OSAS (apnea-hypopnea inde . . .x [AHI] ?5 events/h) and never received therapy. The control group consisted of 34 volunteers (mean age 43.1 ± 11.6 years) in whom OSAS was excluded (AHI Daha fazlası Daha az