Bulunan: 53 Adet 0.001 sn
Koleksiyon [9]
Tam Metin [2]
Yayın Türü [3]
Yazar [20]
Yayın Yılı [9]
Konu Başlıkları [20]
Yayıncı [19]
Yayın Dili [1]
Dergi Adı [20]
Atrial conduction times and left atrial mechanical functions and their relation with diastolic function in prediabetic patients

Gudul N.E. | Karabag T. | Sayin M.R. | Bayraktaroglu T. | Aydin M.

Article | 2017 | Korean Journal of Internal Medicine32 ( 2 ) , pp.286 - 294

Background/Aims: The aim of this study was to investigate atrial conduction times and left atrial mechanical functions, the noninvasive predictors of atrial fibrillation, in prediabetic patients with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). Methods: Study included 59 patients (23 males, 36 females; mean age 52.5 ± 10.6 years) diagnosed with IFG or IGT by the American Diabetes Association criteria, and 43 healthy adults (22 males, 21 females; mean age 48.5 ± 12.1 years). Conventional and tissue Doppler echocardiography were performed. The electromechanical delay parameters were measured from the onset of t . . .he P wave on the surface electrocardiogram to the onset of the atrial systolic wave on tissue Doppler imaging from septum, lateral, and right ventricular annuli. The left atrial volumes were calculated by the disk method. Left atrial mechanical functions were calculated. Results: The mitral E/A and E’/A’ ratios measured from the lateral and septal annuli were significantly lower in the prediabetics compared to the controls. The interatrial and left atrial electromechanical delay were significantly longer in prediabetic group compared to the controls. Left atrial active emptying volume (LAAEV) and fraction (LAAEF) were significantly higher in the prediabetics than the controls. LAAEV and LAAEF were significantly correlated with E/A, lateral and septal E’/A’. Conclusions: In the prediabetic patients, the atrial conduction times and P wave dispersion on surface electrocardiographic were longer before the development of overt diabetes. In addition, the left atrial mechanical functions were impaired secondary to a deterioration in the diastolic functions in the prediabetic patients. © 2017 The Korean Association of Internal Medicine Daha fazlası Daha az

Left main coronary artery atresia and concomitant intercoronary communication

Sayin M.R. | Akpinar I. | Karabag T. | Aydin M. | Dogan S.M. | Gugul N.E.

Article | 2013 | Herz38 ( 7 ) , pp.798 - 800

[No abstract available]

A rare complication during oxcarbazepine use,complete atrioventricular block: Case report

Karabag T. | Aydin M. | Dogan S.M.

Article | 2013 | Turkiye Klinikleri Cardiovascular Sciences25 ( 1 ) , pp.26 - 28

Oxcarbazepine, 10 keto analogue of carbamezepine, is an antiepileptic drug used pri manly for the treatment of focal and generalized tonic clonic seizures in adults and children. Ox carbazepine has been observed to have a positive effect also on psychiatric diseases and trigeminal neuralgia. Oxcarbazepine like most of antiepileptic drugs, inhibits voltage dependent fast sodium channels. During oxcarbazepine treatment, side effects such as hyponatremia, headache, vertigo, somnolence, nausea, double vision, vomiting and ataxia can be seen. However, to date, no specific and!or severe cardiac complications of oxcarbazepine have been rep . . .orted. In this paper, we present a case of complete atrioventricular block that was considered to be caused by oxcarbazepine and that improved after cessation of the drug in a 67 year old female patient with no underlying cardiac etiology. Copyright © 2013 by Türkiye Klinik leri Daha fazlası Daha az

Assessment of QRS duration and presence of fragmented QRS in patients with Behçet's disease

Sayin M.R. | Akpinar I. | Gursoy Y.C. | Kiran S. | Gudul N.E. | Karabag T. | Koca R.

Article | 2013 | Coronary Artery Disease24 ( 5 ) , pp.398 - 403

BACKGROUND: QRS prolongation and the presence of QRS fragmentation in 12-lead ECG are associated with increased mortality and sudden cardiac death in the long term. In this study we aimed to assess QRS duration and fragmentation in patients with Behçet's disease (BD). METHODS: A total of 50 patients (mean age 42.7±12.0 years) previously diagnosed with BD were recruited. In addition, a control group consisting of 50 healthy people (mean age 39.4±12.5 years) was formed. The longest QRS duration was measured in surface 12-lead ECG and QRS complexes were evaluated in terms of fragmentation. Serum C-reactive protein levels were also obta . . .ined. RESULTS: QRS duration and corrected QT duration were significantly longer in patients with BD compared with controls (102.75±11.91 vs. 96.99±10.91 ms, P=0.007; 438.55±30.80 vs. 420.23±28.06 ms, P=0.003, respectively). Fragmented QRS (fQRS) pattern was more common in patients with BD than controls [n=27 (54%) vs. n=16 (32%), P=0.026]. Disease duration was longer in patients with BD with fQRS compared with those without (12.67±8.68 vs. 7.09±7.06 years, P=0.010). Furthermore, C-reactive protein level was higher in patients with BD with fQRS compared with those without (6.53±4.11 vs. 4.97±6.32 mg/dl, P=0.043). Correlation analysis revealed no association between disease duration and QRS duration (r=0.219, P=0.126). CONCLUSION: QRS duration is greater and fQRS complexes are more frequent in patients with BD. These findings may indicate subclinical cardiac involvement in BD. Given the prognostic significance of ECG parameters, it is reasonable to evaluate patients with BD with prolonged and fQRS complexes more in detail such as late potentials in signal averaged ECG in terms of cardiac involvement. © 2013 Wolters Kluwer Health / Lippincott Williams & Wilkins Daha fazlası Daha az

The relationship of age-adjusted Charlson comorbidity ındex and diurnal variation of blood pressure

Kalaycı B. | Erten Y.T. | Akgün T. | Karabag T. | Kokturk F.

Article | 2019 | Clinical and Experimental Hypertension41 ( 2 ) , pp.113 - 117

Backgrounds: Charlson Comorbidity index (CCI) is a scoring system to predict prognosis and mortality. It exhibits better utility when combined with age, age-adjusted Charlson Comorbidity Index (ACCI). The aim of this study was to evaluate the relationship between ACCI and diurnal variation of blood pressure parameters in hypertensive patients and normotensive patients. Methods: We enrolled 236 patients. All patients underwent a 24-h ambulatory blood pressure monitoring (ABPM) for evaluation of dipper or non-dipper pattern. We searched the correlation between ACCI and dipper or non-dipper pattern and other ABPM parameters. To further . . . investigate the role of these parameters in predicting survival, a multivariate analysis using the Cox proportional hazard model was performed. Results: 167 patients were in the hypertensive group (87 patients in non-dipper status) and 69 patients were in the normotensive group (41 patients in non-dipper status) of all study patients. We found a significant difference and negative correlation between AACI and 24-h diastolic blood pressure (DBP), awake DBP, awake mean blood pressure (MBP) and 24-h MBP and awake systolic blood pressure(SBP). Night decrease ratio of blood pressure had also a negative correlation with ACCI (p = 0.003, r = -0.233). However, we found a relationship with non-dipper pattern and ACCI in the hypertensive patients (p = 0.050). In multivariate Cox analysis sleep MBP was found related to mortality like ACCI (p = 0.023, HR = 1.086, %95 CI 1.012–1.165) Conclusion: ACCI was statistically significantly higher in non-dipper hypertensive patients than dipper hypertensive patients while ACCI had a negative correlation with blood pressure. Sleep MBP may predict mortality. © 2018, © 2018 Taylor & Francis Daha fazlası Daha az

First septal artery originating from the left main coronary artery: A rare anomaly

Sayin M.R. | Akpinar I. | Karabag T. | Aydin M. | Dogan S.M.

Note | 2013 | Herz38 ( 4 ) , pp.391 - 392

[No abstract available]

Atypical type of dual left anterior descending coronary artery

Sayin M.R. | Akpinar I. | Karabag T. | Dogan S.M. | Aydin M.

Article | 2013 | Journal of Cardiology Cases8 ( 1 ) , pp.391 - 392

Dual left anterior descending coronary artery (LAD) is a rare coronary anomaly and is divided into six subgroups in the literature according to the origin and course of the short and long branches of the anomalous artery. We present two distinct cases of dual LAD which are distinguished by two branches of equal length from their counterparts in the literature. Learning objective: In our cases a novel dual LAD variant is presented with two main branches of equal length and reaches the cardiac apex. Cardiologists and cardiovascular surgeons should be aware of these variants to avoid misinterpretation of coronary angiography and intrao . . .perative complications. © 2013 Japanese College of Cardiology Daha fazlası Daha az

A case of inadvertent anastomosis of saphenous vein graft to a cardiac vein after coronary bypass surgery

Karabag T. | Dogan S.M. | Sayin M.R. | Akpinar I. | Aydin M.

Article | 2013 | Gazzetta Medica Italiana Archivio per le Scienze Mediche172 ( 01.Feb ) , pp.107 - 108

Iatrogenic anastomosis of saphenous vein graft to cardiac vein after coronary bypass surgery is very rare condition. In this report, a patient presented with recurrent angina late following coronary artery bypass surgery. Investigation revealed an anastomosis between saphenous vein graft and great cardiac vein.

Investigation of the atrial electromechanical delay duration in Behcet patients by tissue Doppler echocardiography

Karabag T. | Aydin M. | Dogan S.M. | Koca R. | Buyukuysal C. | Sayin M.R. | Yavuz N.

Article | 2012 | European Heart Journal Cardiovascular Imaging13 ( 3 ) , pp.251 - 256

Aims: To investigate the atrial electromechanical delay (EMD) duration that is a non-invasive predictor of atrial fibrillation (AF) in patients with Behcet's disease (BD). Methods and results: Thirty-eight Behcet's patients (24 females, 14 males; mean age: 43.6 ± 10.3 years) who were being followed in the dermatology or internal medicine department and 29 demographically matched controls (13 females, 16 males; mean: age 42.6 ± 11.1 years) were included in the study. The inclusion criteria were recurrent oral ulcerations and two of the following features: recurrent genital ulceration, eye lesions, skin lesions or positive pathergy sk . . .in test for Behcet's group. Using tissue Doppler imaging, atrial electromechanical coupling [time interval from the onset of P wave on surface electrocardiogram to the beginning of A wave interval with tissue Doppler echocardiography (PA)] were measured from the lateral mitral annulus (PA lateral), septal mitral annulus (PA septum), and right ventricular tricuspid annulus (PA tricuspid). The mean disease duration was 10.5 ± 7.7 years. The inter-atrial and intra-atrial EMD were significantly higher in the Behcet group than those in the controls (19.8 ± 8.2 vs. 13.1 ± 4.4 ms, P = 0.001; 11.5 ± 7.4 vs. 6.9 ± 3.7 ms, P = 0.02; respectively). The left atrial EMD was similar in both of the groups. However, the P max and PWD values were significantly higher in the BD group compared with those in the controls (120.5 ± 10.1 vs. 112.1 ± 5.9 ms, P < 0.0001; 44.9 ± 10.7 vs. 28.4 ± 5.9 ms, P < 0.0001; respectively). Conclusion: Atrial electromechanical conduction times were increased in the BD patients compared with those in the controls. The tendency of BD patients to go into AF can be easily and non-invasively detected using tissue Doppler echocardiography. These findings may be indicators for subclinical cardiac involvement. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2011 Daha fazlası Daha az

Extreme QT Interval Prolongation Caused by Mad Honey Consumption

Sayin M.R. | Dogan S.M. | Aydin M. | Karabag T.

Article | 2011 | Canadian Journal of Cardiology27 ( 6 ) , pp.8.70E+19 - 8.70E+21

An unusual type of food poisoning, mad honey poisoning, is a well-known phenomenon in the Black Sea region of Turkey. Mad honey poisoning can result in severe cardiac complications including sinus bradycardia, nodal rhythm, various degrees of atrioventricular blocks, and even asystole. However, no cases of long QT interval have been reported so far. This paper reports the first case of extremely long QT interval to be associated with mad honey consumption. © 2011 Canadian Cardiovascular Society.

Effects of folinic acid and fluorouracil chemotherapy on right ventricle functions as assessed with tricuspid annular plane systolic excursion

Bilir C. | Engin H. | Karabag T. | Colak D.

Article | 2014 | Hippokratia18 ( 4 ) , pp.346 - 349

Aim: This study aimed to investigate the effects of folinic acid and fluorouracil (bolus FUFA regimen) chemotherapy on right ventricle (RV) functions. Materials and Methods: Thirty-four gastrointestinal (GI) cancer patients treated with antineoplastic drugs were included the study. All participants received FUFA chemotherapy protocol for colorectal, gastric and pancreatic cancer (i.e. fluorouracil 400-425 mg/m2 intravenous day 1-5 + folinic acid 20-25 mg/m2 intravenous day 1-5 every 28 days x6 cycles) with or without radiation therapy according to the cancer and patient status. All participants have undergone complete physical and l . . .aboratory examination and complete echocardiographic evaluation including detailed right ventricle functional evaluations before the onset of chemotherapy and 6 months after the start of treatment. Results: Mean RV thickness was 0.49 cm before chemotherapy and 0.62 cm at the end of the treatment (p=0.29). Mean tricuspid annular plane systolic excursion (TAPSE) values were 2.08 ± 0.3 and 2.00 ± 0.39 cm, respectively (p=0.25). RV total ejection isovolumic (Tei) index related to the chemotherapy did not change significantly (0.24 and 0.29, respectively, p=0.07). Also we did not find significant chance in the RV end diastolic diameter, RV end systolic diameter, vena cava diameter on inspiration and expiration. Conclusion: Bolus FUFA regimen chemotherapy does not diminish the RV functions as assessed by TAPSE and RV Tei index in GI cancer patients. © 2014, Hippokratia General Hospital of Thessaloniki. All rights reserved Daha fazlası Daha az

Influence of menstrual cycle on P wave dispersion

Karabag T. | Hanci V. | Aydin M. | Dogan S.M. | Turan I.O. | Yildirim N. | Gudul N.E.

Article | 2011 | International Heart Journal52 ( 1 ) , pp.23 - 26

Female gender is an independent risk factor for some types of arrhythmias. We sought to determine whether the menstrual cycle affects P wave dispersion, which is a predictor of atrial fibrillation. The study population consisted of 59 women in follicular phase (mean age, 29.3 ± 7.7 years) (group F) and 53 women in luteal phase (mean age, 28.1 ± 6.8 years) (group L). The ECGs of 35 patients (mean age, 26.4 ± 4.5) were obtained in both follicular and luteal phase. Both groups underwent a standard 12-lead surface electrocardiogram recorded at 50 mm/s. Maximal (Pmax) and minimal P wave durations (Pmin) were measured. P wave dispersion ( . . .PD) was defined as the difference between Pmax and Pmin. PD was significantly higher in group L than group F (46.6 ± 18.5 versus 40.1 ± 12.7; P < 0.05). Pmin was significantly lower in group L than group F (51.6 ± 12.1 versus 59.1 ± 12.1; P = 0.002). When we compared ECGs in different phases of the 35 patients, PD was significantly higher in luteal phase than follicular phase (53.2 ± 12.3 versus 42.8 ± 10.2; P < 0.05). Pmin was significantly lower in luteal phase than follicular phase (47.6 ± 6.6 versus 56 ± 10.1; P = 0.05). We detected a significant correlation between the day of the menses and PD (r = 0.27; P < 0.05). PD was increased in luteal phase compared to follicular phase, and this difference was more prominent as the days of the cycle progressed Daha fazlası Daha az

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