Karabag T. | Dogan S.M.

Makale | 2012 | Catheterization and Cardiovascular Interventions79 ( 1 ) , pp.113 - 116

Spontaneous coronary artery dissection (SCAD) is a rare cause of myocardial ischemia. Multivessel SCAD is much rarer than single vessel involvement and acute coronary syndrome remains the most common clinical presentation of a patient with SCAD. It predominantly occurs in association with atherosclerosis or in the absence of atherosclerosis. We, hereby, present a case of spontaneous multivessel coronary artery dissection in a 35-year-old male patient presenting with chest pain and ventricular tachycardia following emotional stress and discuss the etiology and treatment options. © 2011 Wiley-Liss, Inc. Copyright © 2011 Wiley-Liss, Inc.

Dogan S.M. | Birdane A. | Korkmaz C. | Ata N. | Timuralp B.

Makale | 2007 | Texas Heart Institute Journal34 ( 3 ) , pp.360 - 362

Behçet's syndrome is a chronic multisystem disease that presents with recurrent oral and genital ulceration and recurrent uveitis. Cardiac involvement is an extremely rare manifestation of this disorder. A 33-year-old man with Behçet's syndrome was admitted to our department with a history of cough, fever, chest pain, hemoptysis, and weight loss. Transthoracic and transesophageal echocardiography revealed a right ventricular thrombus. After 1 month of treatment with warfarin, cyclophosphamide, and corticosteroid, the intracardiac thrombus resolved. © 2007 by the Texas Heart® Institute.

Çabuk M. | Dogan S.M. | Erdem Z. | Atik D.Y. | Dogan I.

Makale | 2009 | Anadolu Kardiyoloji Dergisi9 ( 5 ) , pp.360 - 362

[No abstract available]

Karabag T. | Aydin M. | Dogan S.M. | Koca R. | Buyukuysal C. | Sayin M.R. | Yavuz N.

Makale | 2012 | European Heart Journal Cardiovascular Imaging13 ( 3 ) , pp.251 - 256

Aims: To investigate the atrial electromechanical delay (EMD) duration that is a non-invasive predictor of atrial fibrillation (AF) in patients with Behcet's disease (BD). Methods and results: Thirty-eight Behcet's patients (24 females, 14 males; mean age: 43.6 ± 10.3 years) who were being followed in the dermatology or internal medicine department and 29 demographically matched controls (13 females, 16 males; mean: age 42.6 ± 11.1 years) were included in the study. The inclusion criteria were recurrent oral ulcerations and two of the following features: recurrent genital ulceration, eye lesions, skin lesions or positive pathergy sk . . .in test for Behcet's group. Using tissue Doppler imaging, atrial electromechanical coupling [time interval from the onset of P wave on surface electrocardiogram to the beginning of A wave interval with tissue Doppler echocardiography (PA)] were measured from the lateral mitral annulus (PA lateral), septal mitral annulus (PA septum), and right ventricular tricuspid annulus (PA tricuspid). The mean disease duration was 10.5 ± 7.7 years. The inter-atrial and intra-atrial EMD were significantly higher in the Behcet group than those in the controls (19.8 ± 8.2 vs. 13.1 ± 4.4 ms, P = 0.001; 11.5 ± 7.4 vs. 6.9 ± 3.7 ms, P = 0.02; respectively). The left atrial EMD was similar in both of the groups. However, the P max and PWD values were significantly higher in the BD group compared with those in the controls (120.5 ± 10.1 vs. 112.1 ± 5.9 ms, P < 0.0001; 44.9 ± 10.7 vs. 28.4 ± 5.9 ms, P < 0.0001; respectively). Conclusion: Atrial electromechanical conduction times were increased in the BD patients compared with those in the controls. The tendency of BD patients to go into AF can be easily and non-invasively detected using tissue Doppler echocardiography. These findings may be indicators for subclinical cardiac involvement. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2011 Daha fazlası Daha az

Sayin M.R. | Karabag T. | Dogan S.M. | Akpinar I. | Aydin M.

Makale | 2012 | Wiener Klinische Wochenschrift124 ( 07.Aug ) , pp.278 - 281

We herein present a case of a 76-year-old male patient presented with transient ST segment elevation and left bundle branch block caused by mad-honey poisoning. © Springer-Verlag Wien 2012.

Sayin M.R. | Aydin M. | Dogan S.M. | Karabag T. | Cetiner M.A. | Aktop Z.

Makale | 2013 | Herz38 ( 3 ) , pp.299 - 305

OBJECTIVES: The aim of this study was to compare the effects of the new generation ß-blocker anti-hypertensive drugs carvedilol and nebivolol on aortic elastic properties which are important indicators of hypertension-related morbidity and mortality.METHODS: A total of 50 patients who had been diagnosed with stage 1 hypertension according to the Joint National Committee (JNC) VII criteria and who had not received any anti-hypertensive treatment were enrolled in this study. Patients were randomized to receive either 25 mg/day carvedilol (n=25) or 5 mg/day nebivolol (n=25) for 3 months at the beginning of the study. Three patients (1 . . .in the carvedilol group, 2 in the nebivolol group) who did not attend 3 month follow-up measurements were excluded from the study. The study was completed with 47 patients (25 women; mean age: 49 ± 9 years). The aortic elastic parameters such as aortic strain (AS), aortic distensibility (AD), and aortic stiffness index (ASI) were measured by echocardiography.RESULTS: Carvedilol and nebivolol provided a similar decline in both systolic and diastolic blood pressures (-12/-7 mmHg, Daha fazlası Daha az

Sayin M.R. | Akpinar I. | Karabag T. | Dogan S.M. | Aydin M.

Makale | 2013 | Journal of Cardiology Cases8 ( 1 ) , pp.299 - 305

Dual left anterior descending coronary artery (LAD) is a rare coronary anomaly and is divided into six subgroups in the literature according to the origin and course of the short and long branches of the anomalous artery. We present two distinct cases of dual LAD which are distinguished by two branches of equal length from their counterparts in the literature. Learning objective: In our cases a novel dual LAD variant is presented with two main branches of equal length and reaches the cardiac apex. Cardiologists and cardiovascular surgeons should be aware of these variants to avoid misinterpretation of coronary angiography and intrao . . .perative complications. © 2013 Japanese College of Cardiology Daha fazlası Daha az

Ugur M.B. | Dogan S.M. | Sogut A. | Uzun L. | Cinar F. | Altin R. | Aydin M.

Makale | 2008 | ORL70 ( 3 ) , pp.202 - 208

Background/Aims: We aimed to determine the effects of adenoidectomy and/or tonsillectomy (AT) on cardiac functions in children with adenoid and/or tonsillary hypertrophy and obstructive sleep apnea syndrome (OSAS) by using echocardiography with tissue Doppler imaging facility (TDI). Methods: Twenty-nine children with adenoid and/or tonsillary hypertrophy and OSAS and 26 children with primary snoring entered the study. Cardiac functions were assessed by echocardiography with TDI in both groups. Tests were repeated in the OSAS group 6 months after treatment with AT. Results: Echocardiography showed a decrease in estimated pulmonary ar . . .tery systolic pressure from 31 ± 4.2 to 13.1 ± 2.3 (p < 0.001). In TDI, tricuspid Em and E m/Am increased from 11.0 ± 2.7 to 13.5 ± 2.7 cm/s (p < 0.001), and 1.46 ± 0.52 to 1.82 ± 0.53 (p = 0.004), respectively, following AT, indicating improvement in right ventricular diastolic dysfunction. Similarly, mitral Em and Em/A m increased from 12.3 ± 2.1 to 16.3 ± 2.7 cm/s, and from 1.65 ± 0.51 to 2.30 ± 0.54, respectively (p < 0.001). There was no significant difference between postoperative values and control group values. Conclusion: TDI is a technique able to detect diastolic dysfunction unnoticeable by conventional echocardiography. Following AT, we observed improvement in both left and right ventricular diastolic functions using TDI. Copyright © 2008 S. Karger AG Daha fazlası Daha az

Karabag T. | Aydin M. | Dogan S.M.

Makale | 2013 | Turkiye Klinikleri Cardiovascular Sciences25 ( 1 ) , pp.26 - 28

Oxcarbazepine, 10 keto analogue of carbamezepine, is an antiepileptic drug used pri manly for the treatment of focal and generalized tonic clonic seizures in adults and children. Ox carbazepine has been observed to have a positive effect also on psychiatric diseases and trigeminal neuralgia. Oxcarbazepine like most of antiepileptic drugs, inhibits voltage dependent fast sodium channels. During oxcarbazepine treatment, side effects such as hyponatremia, headache, vertigo, somnolence, nausea, double vision, vomiting and ataxia can be seen. However, to date, no specific and!or severe cardiac complications of oxcarbazepine have been rep . . .orted. In this paper, we present a case of complete atrioventricular block that was considered to be caused by oxcarbazepine and that improved after cessation of the drug in a 67 year old female patient with no underlying cardiac etiology. Copyright © 2013 by Türkiye Klinik leri Daha fazlası Daha az

Dogan S.M. | Aydin M. | Gürsürer M. | Dursun A. | Çam F. | Onuk T.

Makale | 2006 | Turk Kardiyoloji Dernegi Arsivi34 ( 6 ) , pp.358 - 362

Objectives: We evaluated the changes in left ventricular function by means of tissue Doppler imaging (TDI) in patients with mitral stenosis (MS). Study design: Standard echocardiographic and TDI studies were performed in 26 patients (18 females, mean age 38±7 years) with severe MS [mitral valve area (MVA) <1.2 cm2], in 32 patients (24 females, mean age 35±9 years) with mild to moderate MS (MVA ?1.2 cm2), and in 25 age-matched healthy volunteers (17 females, mean age 39±6 years). All the patients were in sinus rhythm and none had hypertension or coronary artery disease. Systolic myocardial velocity, early and late diastolic veloci . . .ties were measured in the basal lateral segment and basal interventricular septum from the apical four-chamber views. Results: Left ventricular dimensions, ejection fraction, end-diastolic and end-systolic diameters, and fractional shortening of the left ventricle were similar in all the groups. Patients with MS had significantly decreased peak systolic myocardial velocities in both the lateral wall and interventricular septum of the left ventricle. In addition, early diastolic velocity and the ratio of early/late diastolic velocities were significantly lower. E-wave deceleration time and late diastolic myocardial velocities were similar in three groups. Peak systolic myocardial velocities were significantly correlated with mitral valve areas measured at the septum (r=0.57, p<0.01) and the lateral wall (r=0.48, p<0.01) of the left ventricle. Conclusion: Our results show that, despite the presence of seemingly normal findings on standard echocardiography, TDI may provide evidence for left ventricular systolic dysfunction in patients with MS, representing early signs of myocardial abnormality Daha fazlası Daha az

Dogan S.M. | Gursurer M. | Aydin M. | Gocer H. | Cabuk M. | Dursun A.

Makale | 2006 | International Journal of Cardiology112 ( 3 ) , pp.358 - 362

We present the case of a patient in anomalous origin of the left anterior descending coronary artery that caused myocardial ischemia and led to positive myocardial scintigraphic results. Coronary angiography showed that the left anterior descending coronary artery arose from the right coronary ostium-an anomaly that has been associated with chest discomfort-without atherosclerotic lesions. Left circumflex artery and the diagonal branches were arising from the left main coronary artery and the whole coronary tree were free of atherosclerosis. © 2006 Elsevier Ireland Ltd. All rights reserved.

Karabag T. | Dogan S.M. | Aydin M. | Sayin M.R. | Buyukuysal C. | Gudul N.E. | Demirtas A.O.

Makale | 2012 | Clinical and Investigative Medicine35 ( 1 ) , pp.358 - 362

Purpose: the aim of this study is to investigate whether P wave dispersion (PWD), measured before, during and after fibrinolytic therapy (FT,) is able to predict successful reperfusion and infarct related artery (IRA) patency in patients with acute anterior MI who received FT. Methods: Sixty-eight patients who presented with acute anterior MI were enrolled in the study. An electrocardiogram was performed before and at 30, 60, 90 and 120 minutes after the start of FT. PWD was defined as the difference between maximum and minimum P wave duration on standard 12-lead surface electrocardiogram. A multivariate logistic regression model wa . . .s used to assess whether PWD was predictor of IRA patency and STsegment resolution (STR) on electrocardiogram. Results: PWD 120 was significantly lower in patients with STR on electrocardiogram (38 patients) compared with those without STR (30 patients) (44.8±11.5 vs. 52.9±10.3 ms; p<0.001). PWD 120 was found to be significantly lower in patients with patent IRA (31 patients) compared to those with occluded IRA (37 patients) (42.3±9.7 vs. 53.5±10.6 ms; p<0.001). Logistic regression analysis revealed that PWD120 significantly predicted STR and IRA patency. A ?51.6 ms PWD 120 can predict an occluded IRA with a 87% sensitivity, ?51 ms PWD 120 can predict no reperfusion with a 74% sensitivity. Conclusion: PWD values, which were higher than 51 ms and 51.6 ms in patients who received fibrinolytic therapy, can serve as a marker of failed reperfusion and occluded IRA. PWD values, in combination with other reperfusion parameters, can contribute to the identification of rescue PCI candidates. © 2012 CIM Daha fazlası Daha az