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Bulunan: 58 Adet 0.122 sn
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Traumatic neuromas: A histopathologic and immunohistochemical study [Travmatik nöromalar: Histopatolojik ve i·mmünohistokimyasal bir çalişma]

Özdamar Ş.O. | Dogan Gün B. | Barut F. | Bahadir B.

Objective: Traumatic neuroma is an exuberant, probably non-neoplastic proliferation of a nerve occurring in response to injury or surgery. We studied six cases of traumatic neuroma with light microscopic, histochemical and immunohistochemical methods to assess the cellular compositions of these lesions. Material and Methods: Sections from the formalin-fixed parafin-embedded tissues were stained with hematoxylin-eosin, Gomori's trichrome, Verhoeff elastica-von Gieson, reticuline, and S-100 protein, Epithelial Membrane Antigen, CD34 and CD68. Results: All cases revealed large numbers of small an ...Daha fazlası

The oncocytic variant of papillary thyroid carcinoma with multifocal involvement: A case report

Barut F. | Özdamar Ş.O. | Bektaş S. | Taşcilar Ö. | Dogan Gün B.

The oncocytic variant of papillary thyroid carcinoma is an uncommon form of neoplasm, the clinicopathological features and biological behavior of which have not been precisely defined. The pattern of multifocal growth is an uncommon feature. The case was a 64-year-old female patient with multinodular goiter who had undergone total thyroidectomy. Microscopic examination of cross-sections of the multiple nodules revealed a tumoral lesion characterized by a predominant follicular growth pattern, and sparse, small, abortive papillary structures. Most of the tumor cells also displayed the classical ...Daha fazlası

Pulmonary and central nervous system involvement in sweet's syndrome: A very rare case report

Aydemir H. | Öztoprak N. | Celebi G. | Altinyazar C. | Barut F. | Piskin N. | Akduman D.

Sweet's syndrome is a multisystem inflammatory disorder characterized by painful, erythematous plaques and aseptic neutrophilic infiltration of various organs. The absence of vasculitis is a histological criterion for diagnostic, but recent reports suggest that vasculitis can occur in Sweet's syndrome. Involvement of the central nervous system and the pulmonary system is very rare. In this case study we describe a chronic alcoholic man with Sweet's syndrome associated with acute-onset encephalitis and severe pulmonary involvement. The patient's symptoms responded dramatically to steroid treatm ...Daha fazlası

Effects of humanin on experimental colitis induced by 2,4,6-trinitrobenzene sulphonic acid in rats

Gultekin F.A. | Emre A.U. | Celik S.K. | Barut F. | Tali U. | Sumer D. | Turkcu U.O.

Background/Aim: The excessive apoptosis of intestinal epithelial cells (IECs) partly accounts for the development of colonic inflammation and eventually results in ulcerative colitis (UC). Humanin, an endogenous anti-apoptotic peptide, has previously been shown to protect against Alzheimer's disease and a variety of cellular insults. The present study aimed to investigate the effects of glysin variant of humanin (HNG) on 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced colitis in rats. Materials and Methods: Rats were divided into four groups as follows: Group 1 (n = 8): control; isotonic s ...Daha fazlası

Coexistence of cervico-thoracic extradural en-plaque meningioma with multiple intracranial meningiomas

Kale A. | Akyol Ç. | Keskin E. | AydoğmuŞ E. | Ali Aydin H. | Barut F. | Gül Ş.

Meningioma is one of the most common tumors in the spinal cord. Extradural and en-plaque variety of meningioma occur less frequently. A 47-year-old woman is presented with radiculopathy signs. Magnetic resonance imaging revealed a lesion from C6 through T3 vertebral levels compressing the cord both anteriorly and posteriorly. Subtotally excision was performed and histopathologic signs showed transitional type of meningioma (WHO Grade 1). Post operatively, she had good neurological recovery. Intraoperative findings point out that the en-plaque meningioma was pure extradural. Twelve cases of pur ...Daha fazlası

Does intraabdominal use of Ankaferd Blood Stopper cause increased intraperitoneal adhesions? [Ankaferd Blood Stopper'in karin içi kullanim periton içi yapişklk oluşumunu arttrr m?]

Cömert M. | Karakaya K. | Barut F. | Karadeniz Çakmak G. | Uçan H.B. | Gültekin F.A. | Emre A.U.

Background The aim of this study was to investigate whether intraabdominal Ankaferd Blood Stopper (ABS) causes increased intraabdominal adhesion formation and to determine any side effects of ABS in vivo. Methods The present experimental study was designed to examine the effects of Ankaferd solution on peritoneal adhesion formation in a rat model of cecal abrasion. Intraperitoneal adhesions were assessed macroscopically and histopathologically on the 10th postoperative day. The possible adverse affects of ABS on liver and lung tissues were analyzed histopathologically, and blood chemistry was ...Daha fazlası

Gastroprotective effects of CoQ10 on ethanol-induced acute gastric lesions

Karakaya K. | Barut F. | Hanci V. | Can M. | Comert M. | Ucan H.B. | Cakmak G.K.

Introduction: Alcohol consumption is frequently associated with gastric mucosal lesions. The purpose of this study was to determine the effect of Coenzyme-Q10 (CoQ10) supplementation on the ethanol-induced gastric mucosal damage in a rat model. Material and method: Sixty-four female wistar albino rats were randomly divided into 8 groups (n = 8). Studies were performed in ethanol induced gastric ulcer model in Wistar albino rats. Famotidine at a dose of 5 mg/kg or 20 mg/kg and CoQ10 at a single dose of 10 mg/kg or 20 mg/kg and 30 mg/kg for 7 days were administered as pretreatment. All the rats ...Daha fazlası

Placental chorangiosis: The association with oxidative stress and angiogenesis

Barut A. | Barut F. | Kandemir N.O. | Aktunc E. | Arikan I. | Harma M. | Harma M.I.

Background/Aims: Chorangiosis is considered to be strongly associated with fetal, maternal, and placental disorders, and has been found to be correlated with increased fetal morbidity and mortality. In this study, it is aimed to investigate the association of angiogenesis and oxidative stress with the pathogenesis of chorangiosis. Methods: Expressions of heat shock protein 70 (HSP70), vascular endothelial growth factor-A (VEGF-A) and basic fibroblast growth factor (b-FGF), which are investigated with avidin-biotin-peroxidase method in formalin-fixed, paraffin-embedded sections from placental t ...Daha fazlası

Epicardial mass causing cardiac compression: An unusual involvement in lymphomatoid granulomatosis

Karabag T. | Aydin M. | Barut F. | Buyukates M. | Dogan S.M. | Celik O. | Sayin M.R.

Lymphomatoid granulomatosis is a rare, diffuse, large B-cell lymphoma that is positive for Epstein-Barr virus. A multiorgan process, it manifests itself chiefly in the lungs but can also affect the skin, nervous system, and kidneys. Cardiac involvement and pericardial effusion are very unusual. We report the case of a 62-year-old man with lymphomatoid granulomatosis involving the heart and lungs. Diagnosis was confirmed with wedge biopsy at pericardiotomy, and the patient was treated with cyclophosphamide, prednisolone, and vincristine. Although the patient was still symptomatic at 6-month fol ...Daha fazlası

Cystain C and neuropeptid Y levels in brain tissues after experimental subarachnoid hemorrhage

Açikgöz S. | Can M. | Güven B. | Edebali N. | Barut F. | Büyükuysal Ç. | Tekin I.Ö.

The aim of this study was to investigate the changes in the levels of cystatin C, which protects neurodegeneration in the central nervous system with the inhibition of cysteine protease and by inducing autophagy in the pathogenesis of cerebral vasospasm and levels of vasoconstrictive neuropeptid Y (NPY) in the brain tissue homogenates of rat model of subarachnoid hemorrhage (SAH). Three experimental groups were used: Day 2 and Day 7 groups after SAH, and also a control group. There were seven Wistar albino rats in each group. SAH was accomplished by transclival basilar artery puncture. Rat cys ...Daha fazlası

Ovarian heterotopic pregnancy clinically mimicking endometrioma

Onak Kandemir N. | Barut F. | Yurdakan G. | Bayar Ü. | Özdamar Ş.O.

Heterotopic pregnancy is a very uncommon entity with a difficult preoperative diagnosis. In the present study, we presented an ovarian heterotopic pregnancy case, clinically mimicking endometrioma developed in a 33-year-old female following an in vitro fertilization procedure. The importance of clinical, histopathological, and immunohistochemical examinations in the diagnosis of heterotopic pregnancy are emphasized.

Comparison of the diagnostic results of bronchoalveolar lavage with synchronous transbronchial biopsies [Bronkoalveoler lavaj-transbronşiyal biyopsi tanilarinin karşilaştirilmasi]

Barut F. | Özdamar Ş.O. | Bahadir B. | Dogan Gün B. | Bektaş S. | Çolak S. | Mocan Kuzey G.

Objective: Bronchoalveolar lavage performed during bronchoscopic examination is a type of cytologic sampling with great diagnostic significance. Its diagnostic value is enhanced when biopsy is unavailable and bronchoalveolar lavage is the unique sample. Determining the diagnostic accuracy of bronchoalveolar lavage by comparing it with the diagnostic yield of synchronous biopsies is an indicator of its effectiveness. Material and Methods: In this study, 435 bronchoalveolar lavage and 273 bronchoscopic biopsy specimens obtained from January 2003 to December 2005 in the Department of Pulmonary Di ...Daha fazlası

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